Antibiotics in head and neck surgery in the setting of malnutrition, tracheotomy, and diabetes

Sepehr, Ali; Santos, Barbara‐Jean Gutierrez; Chou, Chinsui; Karimi, Koohyar; Devcic, Zlatko; Oels, Stefanie; Armstrong, William B.

doi:10.1002/lary.20078

Cited by 44 publications

(50 citation statements)

References 14 publications

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“…Studies of cleancontaminated head and neck procedures found no difference in efficacy between regimens of 24 hours and longer regimens of three, five, or seven days. [499][500][501]505,507,512,524,[531][532][533][534] Limited data exist on single-dose prophylaxis in these procedures.…”

Section: Head and Neck Proceduresmentioning

confidence: 98%

“…Similar results were reported in several additional small, uncontrolled studies. 500,[527][528][529] Choice of agent. Several randomized, single-center studies have compared antimicrobial regimens for clean-contaminated procedures.…”

Section: Head and Neck Proceduresmentioning

confidence: 99%

“…498 Postoperative SSI rates are affected by age, nutritional status, and the presence of concomitant medical conditions such as diabetes mellitus, anemia, and peripheral vascular disease. 496,[499][500][501][502][503][504] Use of tobacco, 498,505 alcohol, 505,506 or drugs of abuse 507 has also been associated with a higher risk of postoperative infection, particularly in patients with mandibular fracture. The hospital course, including length of hospitalization before operation, duration of antimicrobial use before operation, length of operation, presence of implants, and previous tracheotomy can also affect postoperative SSI rates.…”

Section: Head and Neck Proceduresmentioning

confidence: 99%

See 2 more Smart Citations

Clinical practice guidelines for antimicrobial prophylaxis in surgery

Bratzler

Dellinger

Olsen

et al. 2013

American Journal of Health-System Pharmacy

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1,464

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Section: Head and Neck Proceduresmentioning

confidence: 98%

Section: Head and Neck Proceduresmentioning

confidence: 99%

Section: Head and Neck Proceduresmentioning

confidence: 99%

See 1 more Smart Citation

Clinical practice guidelines for antimicrobial prophylaxis in surgery

Bratzler

Dellinger

Olsen

et al. 2013

American Journal of Health-System Pharmacy

1,836

1,464

View full text Add to dashboard Cite

“…Individual patient-specific factors that might influence the risk of postoperative wound infection, are for example age, nutritional status, comorbidities such as diabetes mellitus, anemia, and peripheral vascular diseases, but also tobacco abuse, alcohol abuse, and medication [238], [239], [240], [241], [242], [243], [244], [245]. The presence of malignant disease is also a risk factor for the occurrence of wound infection.…”

Section: Evidence Of Perioperative Antibiotic Therapy In the Contexmentioning

confidence: 99%

Evidence and evidence gaps of laryngeal cancer surgery

Wiegand

2016

GMS Current Topics in Otorhinolaryngology - Head and Neck Surgery; 15:Doc03

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“…CAİ için risk faktörleri yaş, beslenme durumu, diabetes mellitus, anemi, periferik vasküler hastalık, preoperatif radyasyon ve/veya kemoterapi, sigara ve alkol kullanımıdır (40)(41)(42). Radikal ya da bilateral boyun diseksiyonu ve myokutanöz flep ya da mikrovasküler serbest fleplerle rekonstrüksiyon operasyonları CAİ açısından riskli prosedürlerdir (40,42).…”

Section: Baş-boyun Cerrahisiunclassified

Current Recommendations on Surgical Antimicrobial Prophylaxis

Turan¹

2015

Klimik Dergisi

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ÖzetCerrahi alan infeksiyonu (CAİ), hastanede yatan ameliyat geçir-miş hastalardaki en sık, hastanede yatan tüm hastalar arasın-da ise üçüncü sırada görülen nozokomiyal infeksiyondur. CAİ, hastaların daha fazla antibiyotik almasına, tedavi maliyetlerinin artmasına ve hastanede kalma süresinin uzamasına neden olmaktadır. Antimikrobiyal profilaksi CAİ'yi önlemede uygulanan en etkili yöntemlerden birisidir. Cerrahi antimikrobiyal profilaksi uygulaması sırasında, indikasyonun yanlış olması, antimikrobiyal ilaçların veriliş zamanının yanlış olması, gereksiz uzun süreli uygulama ve yanlış antimikrobiyal ilaç seçimi gibi hatalar yapıl-maktadır. Bu derlemede güncel rehberler ışığında başlıca CAİ, epidemiyolojisi, risk faktörleri ve cerrahi antimikrobiyal profilaksi konuları irdelenmiştir. AbstractBeing the most common nosocomial infections among hospitalized surgical patients, surgical site infections (SSIs) are also the third most common nosocomial infection among all hospitalized patients. These infections result in consumption of more antibiotics, an increase in the cost of care, and a prolongation of hospital stay. Antimicrobial prophylaxis is one of the most effective methods used in preventing SSIs. It is known that incorrect indication, incorrect application time of the antimicrobial drugs, unnecessarily long term application, and incorrect drug selection are some of the mistakes made during the application of surgical antimicrobial prophylaxis. In this review, epidemiological findings and risk factors of SSIs and surgical antimicrobial prophylaxis are discussed in the light of current guidelines. GirişCerrahi alan infeksiyonu (CAİ) hastane kaynaklı olarak ortaya çıkan infeksiyonların önde gelen nedenlerindendir. CAİ, cerrahi operasyon yapılan hastalarda %38 oranında ve en sık görülen nozokomiyal infeksiyon olarak karşımıza çıkmaktadır. ABD'de her yıl cerrahi uygulanan 30 milyondan fazla hastanın %2-3'ünde CAİ geliştiği tahmin edilmektedir (1). Bu tür infeksiyonlarda morbidite ve mortalite artışı olmakta, hastanede yatış süresi uzamakta, antibiyotik kullanımı artmakta, sonuçta hasta ve ödeme yapan kurumlara ek mali yükler gelmektedir (2). Antimikrobiyal profilaksi, CAİ'yi önlemede uygulanan en etkili yöntemlerden birisidir (3). Bu derlemede, cerrahi antimikrobiyal profilaksi üzerine güncel önerileri sunmak amacıyla American Society of Health-System Pharmacists (AHSP), Infectious Diseases Society of America (IDSA), Surgical Infection Society (SIS), Society for Healthcare Epidemiology of America (SHEA), Scottish Intercollegiate Guidelines Network (SIGN), National Institute for Health and Care Excellence (NICE) ve UpToDate rehberleri gözden geçirilmiştir (4,(6)(7)(8). Cerrahi Alan İnfeksiyonu RiskiCerrahi operasyon öncesi ve sırasında uygulanan asepsi ve alınan antisepsi önlemlerinin infeksiyon oranlarını önemli ölçüde azalttığı birçok çalışmada göste-rilmiştir. İnfeksiyon oranlarını ve dolayısıyla morbidite ve mortalite hızlarını azaltan bu uygulamalar, cerrahi girişimlerde uygulanan rutin uygulamalardır. Antimik...

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Antibiotics in head and neck surgery in the setting of malnutrition, tracheotomy, and diabetes

Abstract: Malnutrition and tracheotomy were associated with a higher infection rate while diabetes was not found to be a risk factor. Prolonged antibiotics were not associated with a lower infection rate in the overall group or in any subgroup.

Cited by 44 publications

References 14 publications

Clinical practice guidelines for antimicrobial prophylaxis in surgery

Clinical practice guidelines for antimicrobial prophylaxis in surgery

Evidence and evidence gaps of laryngeal cancer surgery

Current Recommendations on Surgical Antimicrobial Prophylaxis

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