Antibiotic use in Vietnamese hospitals: A multicenter point-prevalence study

Thư, Trương Anh; Rahman, Mahbubur; Coffin, Susan; Harun-Or-Rashid, Md.; Sakamoto, Junichi; Hùng, Nguyễn Việt

doi:10.1016/j.ajic.2011.10.020

Cited by 94 publications

(102 citation statements)

References 17 publications

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“…Results demonstrated that 84% of the antibiotic-treated cases at the time of sampling in these hospitals were using cephalosporins, mainly cefotaxime, a third-generation cephalosporin antibiotic. This result was similar to previous studies conducted in Vietnam [11][12][13][14]and in the world [5,7].14% of inpatients in this study received at least two antibiotics, most of them were given two antibiotics. The most common antibiotic combinations were cephalosporins plus gentamycin, and two antibiotics belonging to the cephalosporin class (cefotaxime and ceftazidime).…”

Section: Discussionsupporting

confidence: 82%

“…Studies, which investigated the use of antibiotics, recent years revealed that cephalosporins were prescribed more frequently in the treatment of infections in the world [2][3][4][5][6][7]and in Vietnam as well [8][9][10][11][12][13][14][15]. However, in the current context of antibiotic resistance crisis, particularly the burgeoning resistance to cephalosporins [16], antimicrobial stewardship programs have become a prerequisite committed at all the healthcare centers.…”

Section: Introductionmentioning

confidence: 99%

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Injectable Cephalosporins Usein Vietnamese Hospitals:a Descriptive Cross-Sectional Multicenter Study

Nhac-Vu

Ngoc-Van²

2017

Int J Pharm Pharm Sci

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Objective: The objective of this research was to investigate the use of injectable cephalosporins for inpatients at eleven hospitals in An-Giang province, Vietnam. Methods:This cross-sectional multicenter study was conducted through retrieving the medical inpatient data at eleven hospitals in An-Giang province over the 01-12/2015 period. Results:The sample included 23155 treatment episodes with cephalosporins. Among them, 86% wereused only one agent of cephalosporins, mainly cefotaxime. Among cases administrated concurrentlydifferent antibiotic classes, combinations of cephalosporins and gentamycin were the majority. All treatment episodes correlated with sixteen indication groups of infection treatment, in which the leading groups were "pneumonia", "gastrointestinal infections" and "cesarean" according to the numbers of treatment episodesand the costs of cephalosporins used. 6.61 billion VND was spent for cephalosporins which accounted for 98 % of the total injectable antibiotic cost over the twelve-month period at eleven hospitals in An-Giang. Conclusion:Analysis of injectable cephalosporins consumption, and multicenter approach, has a crucial importance for further survey of antibiotic de-escalation protocol in hospitals in An-Giang.

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Section: Discussionsupporting

confidence: 82%

Section: Introductionmentioning

confidence: 99%

Injectable Cephalosporins Usein Vietnamese Hospitals:a Descriptive Cross-Sectional Multicenter Study

Nhac-Vu

Ngoc-Van²

2017

Int J Pharm Pharm Sci

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“…Although there have been several large PPS of hospital AMU in the United States [11, 12], Europe [13], Australia [14, 15], and elsewhere [16, 17], PPS of Canadian hospitals are more limited, and are particularly lacking for nonacademic centers [18–20]. To our knowledge, there is also only 1 example of a provincial PPS, conducted in New Brunswick in 2012 [21, 22].…”

mentioning

confidence: 99%

Evaluating Antimicrobial Use and Spectrum of Activity in Ontario Hospitals: Feasibility of a Multicentered Point Prevalence Study

Leung

Langford

et al. 2018

Open Forum Infectious Diseases

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BackgroundAntimicrobial stewardship, a key component of an overall strategy to address antimicrobial resistance, has been recognized as a global priority. The ability to track and benchmark antimicrobial use (AMU) is critical to advancing stewardship from an organizational and provincial perspective. As there are few comprehensive systems in Canada that allow for benchmarking, Public Health Ontario conducted a pilot in 2016/2017 to assess the feasibility of using a point prevalence methodology as the basis of a province-wide AMU surveillance program.MethodsThree acute care hospitals of differing sizes in Ontario, Canada, participated. Adults admitted to inpatient acute care beds on the survey date were eligible for inclusion; a sample size of 170 per hospital was targeted, and data were collected for the 24-hour period before and including the survey date. Debrief sessions at each site were used to gather feedback about the process. Prevalence of AMU and the Antimicrobial Spectrum Index (ASI) was reported for each hospital and by indication per patient case.ResultsParticipants identified required improvements for scalability including streamlining ethics, data sharing processes, and enhancing the ability to compare with peer organizations at a provincial level. Of 457 patients, 172 (38%) were receiving at least 1 antimicrobial agent. Beta-lactam/beta-lactamase inhibitors were the most common (18%). The overall mean ASI per patient was 6.59; most cases were for treatment of infection (84%).ConclusionsThis pilot identified factors and features required for a scalable provincial AMU surveillance program; future efforts should harmonize administrative processes and enable interfacility benchmarking.

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“…Although a global increase in the number of resistant bacteria necessitates the use of potent antibiotics to combat serious infections and the use of antibiotics is necessary and lifesaving in ill infants and neonates, irrational antimicrobial prescription in situations where antibiotics are misused, is widespread globally, especially in developing countries (5)(6)(7).…”

mentioning

confidence: 99%

Antibiotic Prescribing Pattern in Neonates of Seventeen Iranian Hospitals

Fahimzad

Eydian

Karimi

et al. 2017

Arch Pediatr Infect Dis

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Background: The association between the use of antibiotics and bacterial resistance has obviously been established and it seems to be a significant problem for public health. It is clear that irrational use and high rates of antibiotic prescription are associated with increased bacterial resistance. As antibiotics are the class of drugs commonly prescribed in neonatal and Neonatal Intensive Care Unit (NICU) wards, neonates are at high risk of opportunistic or nosocomial infections due to prolonged hospitalization and immunosuppressed condition. Objectives: It is essential for antibiotic prescription patterns to be evaluated periodically for rational use. Therefore, the present study was carried out to identify the prescribing patterns of antibiotics in neonatal and NICU wards of 17 different Iranian hospitals. Methods: The study was done during 1 calendar week between January and February 2014. All in-patients admitted to the NICU and neonatal units of 17 Hospitals in 15 Iranian cities were included. Relevant data of all neonates receiving an antibiotic at 8 am on the day of the study was collected by trained members of the study team; age of the patients, type and number of administered antibiotics, route of administration, underlying disease, and indication for use were documented.

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Antibiotic use in Vietnamese hospitals: A multicenter point-prevalence study

Cited by 94 publications

References 17 publications

Injectable Cephalosporins Usein Vietnamese Hospitals:a Descriptive Cross-Sectional Multicenter Study

Injectable Cephalosporins Usein Vietnamese Hospitals:a Descriptive Cross-Sectional Multicenter Study

Evaluating Antimicrobial Use and Spectrum of Activity in Ontario Hospitals: Feasibility of a Multicentered Point Prevalence Study

Antibiotic Prescribing Pattern in Neonates of Seventeen Iranian Hospitals

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