Antibiotic usage and resistance in animal production in Vietnam: a review of existing literature

Di, Khanh Nguyen; Phạm, Duy Toàn; Tee, Tay Sun; Binh, Quach An; Nguyen, Thanh Cong

doi:10.1007/s11250-021-02780-6

Cited by 17 publications

(12 citation statements)

References 38 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…It has been widely documented as a barrier to addressing AMR in communities that antibiotics are not clearly recognized and the concept of AMR is not well understood ( 69 , 70 ). In our study we found that there was low awareness and low perceived importance of AMR in the community, and this made engagement on the issue particularly challenging.…”

Section: Discussionmentioning

confidence: 99%

Challenges and Lessons Learned in the Development of a Participatory Learning and Action Intervention to Tackle Antibiotic Resistance: Experiences From Northern Vietnam

Cai

Tran

Nguyen

et al. 2022

Front. Public Health

View full text Add to dashboard Cite

Antibiotic use in the community for humans and animals is high in Vietnam, driven by easy access to over-the counter medicines and poor understanding of the role of antibiotics. This has contributed to antibiotic resistance levels that are amongst the highest in the world. To address this problem, we developed a participatory learning and action (PLA) intervention. Here we describe challenges and lessons learned while developing and testing this intervention in preparation for a large-scale One Health trial in northern Vietnam. We tested the PLA approach using community-led photography, and then reflected on how this approach worked in practice. We reviewed and discussed implementation documentation and developed and refined themes. Five main themes were identified related to challenges and lessons learned: understanding the local context, stakeholder relationship development, participant recruitment, building trust and motivation, and engagement with the topic of antibiotics and antimicrobial resistance (AMR). Partnerships with national and local authorities provided an important foundation for building relationships with communities, and enhanced visibility and credibility of activities. Partnership development required managing relationships, clarifying roles, and accommodating different management styles. When recruiting participants, we had to balance preferences for top-down and bottom-up approaches. Building trust and motivation took time and was challenged by limited study team presence in the community. Open discussions around expectations and appropriate incentives were re-visited throughout the process. Financial incentives provided initial motivation to participate, while less tangible benefits like collective knowledge, social connections, desire to help the community, and new skills, sustained longer-term motivation. Lack of awareness and perceived importance of the problem of AMR, affected initial motivation. Developing mutual understanding through use of common and simplified language helped when discussing the complexities of this topic. A sense of ownership emerged as the study progressed and participants understood more about AMR, how it related to their own concerns, and incorporated their own ideas into activities. PLA can be a powerful way of stimulating community action and bringing people together to tackle a common problem. Understanding the nuances of local power structures, and allowing time for stakeholder relationship development and consensus-building are important considerations when designing engagement projects.

show abstract

Section: Discussionmentioning

confidence: 99%

Challenges and Lessons Learned in the Development of a Participatory Learning and Action Intervention to Tackle Antibiotic Resistance: Experiences From Northern Vietnam

Cai

Tran

Nguyen

et al. 2022

Front. Public Health

View full text Add to dashboard Cite

show abstract

“…The reason behind the extremely high rates of resistance to these two drugs in Vietnam could be their widespread over-thecounter utilization. Metronidazole and clarithromycin are easily purchased in any pharmacy or drug store in Vietnam, without prescriptions, and they are not only used to treat HP but also other infections [11], [12]. More importantly, metronidazole and clarithromycin are considered the first-line therapies for HP infection in Asian countries [20].…”

Section: Discussionmentioning

confidence: 99%

“…However, the success rates of these regimens are varied and dependent on many factors, including patient compliance, smoking, and antibiotic resistance [8], [9], [10]. Antibiotic resistance, one of the biggest risks to global health that is mainly due to the misuse of antibiotics in animals and humans, has been found in increasingly many types of bacteria [11], [12]. The World Health Organization (WHO) has confirmed that HP is one of 16 types of antibiotic-resistant bacteria that pose the greatest threat to human health [13].…”

Section: Introductionmentioning

confidence: 99%

Evaluation of the Antibiotic Resistance Rate of Helicobacter pylori in Peptic Ulcer Patients in Tien Giang Central General Hospital, Tien Giang Province, Vietnam

Nhu

Nguyen

Tran

et al. 2022

Open Access Maced J Med Sci

View full text Add to dashboard Cite

BACKGROUND: Peptic ulcer (PU), trauma on the lining of the stomach and/or small intestine, is among the top five reasons for hospitalization in Tien Giang, a province in the South of Vietnam. Since Helicobacter pylori (HP) is one of the main causes of PU, its features, especially the antibiotic-resistant status, have critical significance in PU treatment. AIM: This study evaluates the HP infection prevalence, HP antibiotic resistance rate, and its associations with the patients’ sociodemographic characteristics. MATERIALS AND METHODS: A cross-sectional study was conducted on PU patients in Tien Giang province, Vietnam, from June 2020 to June 2021. The volunteers were tested for HP infection and antibiotic resistance using three methods, where appropriate, including Gram staining, CLO (urease) test, and bacterial culture method. RESULTS: Among 368 samples, 31.5% had infected with antibiotic-resistant HP. The resistance rates to five antibiotics commonly used in HP treatment, including metronidazole, clarithromycin, tetracycline, levofloxacin, and amoxicillin, were 96.6%, 94.8%, 70.7%, 61.2%, and 53.4%, respectively. The rates of tetracycline and clarithromycin resistance were related to alcohol consumption (t-test, p < 0.05). The HP treatment history was significantly associated with the levofloxacin resistance (t-test, p < 0.05). CONCLUSIONS: The emergence of antibiotic-resistant HP is a major public health concern in Tien Giang, Vietnam. This issue should be tackled at the national level to avoid the further spread of these multi-drug resistant HP strains.

show abstract

“…Interestingly, the product effects on the standard bacterial strains were much higher than the acne-sample isolated ones. This is due to the fact that bacteria in acne samples have gained antibacterial resistant property (i.e., less sensitive to the antibacterial agents) as a results of irrational uses of antibiotics in Vietnam [40][41] . Lastly, the fact that the hydrogels possessed better antibacterial effects than the positive controls (vancomycin and colistin for gram-positive and gram-negative bacteria, respectively) might, again, be explained by the resistance of the tested bacteria against these commercial drugs.…”

Section: Pharmaceutical Sciences Asiamentioning

confidence: 99%

Antibacterial hydrogel containing Piper Betel L. extract for acne treatment, an ex vivo investigation

Pujari¹,

Subramanian²,

Rao³

2022

Pharm Sci Asia

View full text Add to dashboard Cite

Acne vulgaris and acne-like disorders such as gramnegative folliculitis (herein preferred as acne for the entire article), are uncomfortable facial skin problems that possesses a prevalence of 80% in adults 1 . This disease significantly decreases the patient self-confidence and self-esteem, especially in teenagers. There are 4 common causes of acne, namely high sebum production, pilosebaceous follicles keratinization, uncontrolled bacterial growth, and immune-response inflammation. Among them, acne caused by bacteria such as the gram-positive Staphylococcus aureus (S. aureus) (for acne vulgaris) and gram-negative Escherichia coli (E. coli) (for gramnegative folliculitis), are often serious and demand urgent treatments 2-5 . Nevertheless, these treatments, including topical benzoyl peroxide, topical/oral antibiotics, topical retinoids, and isotretinoin, although effective, cause lots of unwanted side effects that pose a significant health risks in patients [6][7] . Thus, numerous alternative approaches have been investigated, namely utilizing the natural plant extracts [8][9][10][11][12][13] . For instance, the green tea polyphenols demonstrates antibacterial action in acne infections and reduce the dermal sebum secretion 11 . To this end, an interesting plant that has gained much attention is the Piper betle L.Belong to the family Piperaceae, Piper betle (Betel vine, Betel, Betle, "Trầu không" [in Vietnamese]), originated from Central and East Malaysia and has been cultivated for more than 2500 years [14][15] , is a popular plant in

show abstract

Antibiotic usage and resistance in animal production in Vietnam: a review of existing literature

Cited by 17 publications

References 38 publications

Challenges and Lessons Learned in the Development of a Participatory Learning and Action Intervention to Tackle Antibiotic Resistance: Experiences From Northern Vietnam

Challenges and Lessons Learned in the Development of a Participatory Learning and Action Intervention to Tackle Antibiotic Resistance: Experiences From Northern Vietnam

Evaluation of the Antibiotic Resistance Rate of Helicobacter pylori in Peptic Ulcer Patients in Tien Giang Central General Hospital, Tien Giang Province, Vietnam

Antibacterial hydrogel containing Piper Betel L. extract for acne treatment, an ex vivo investigation

Contact Info

Product

Resources

About