Antibiotic Susceptibility Patterns of Bacterial Isolates from Pus Samples in a Tertiary Care Hospital of Punjab, India

Abstract

We determined the prevalence and antibiotic susceptibilities patterns of bacterial isolates from pus samples collected from patients in a tertiary care hospital of Punjab, India. E. coli was the most prevalent pathogen (51.2%) followed by Staphylococcus aureus (21%), Klebsiella pneumoniae (11.6%), Pseudomonas aeruginosa (5.8%), Citrobacter spp. (3.5%), Acinetobacter baumannii (2.3%), Proteus mirabilis (2.3%), and Streptococcus spp. (2.3%). E. coli, K. pneumoniae, A. baumannii, and Citrobacter isolates were resistant to multiple antibiotics including higher generation cephalosporins. S. aureus and Streptococcus isolates were sensitive to cloxacillin and vancomycin. However, P. aeruginosa, P. mirabilis, and Streptococcus isolates were found to be less resistant to the spectrum of antibiotics tested. Overall, our findings indicate the prevalence of resistance to different classes of antibiotics in bacterial isolates from pus infections and hence highlight the need for effective surveillance, regulator reporting, and antibiogram-guided antibiotic prescription.

Microbial Profile and Antimicrobial Susceptibility Pattern of Pus Culture Isolates from a Teaching Tertiary Care Hospital, South India

“…In this study, the pus culture positivity rate in clinically suspected cases was 59.92% which is comparable to the previous reports of Rai et al, (2017) (59%) and Trojan et al, (2016) (60.1%). The male: female distribution of pus isolates was found to be 1.30:1 while the study of Rao et al, 2014 showed 1.43:1 ratio.…”

“…Since these infections are associated with high morbidity prompt antibiotic therapy is mandatory. An increase incidence of multidrug resistant Gram negative bacteria and Methicillin resistant Staphylococcus aureus is frequently isolated from pyogenic infections under hospital settings (Muluye et al, 2014;Trojan et al, 2016). The emergence of antibiotic resistant pathogens poses a grave threat to the health care system.…”

Impact of Some Antibiotics on Bacteria Isolated from Appendices in Kirkuk Province, Iraq

“…Similar results, with a subtle difference, were found elsewhere too [30] another study in Egypt [31]. Our Citrobacter youngae, showed resistance to almost all the antibiotics tested are in concomitant with some recent studies [38] [39] [40]. The Pseudomonas aeruginosa was resistance to Piperacillin, Ceftazidime, Ampicillin, Azteroname, Augmentin and Cephalothin [31] [36].…”

Isolation and Molecular Identification of Staphylococcus Spp. From Bovine Mastitis Milk Samples.

“…Majority of mastitis causing pathogens are normally found intermediate resistant to the antimicrobials used for treatment, but in past two decades few studies have signposted an augmented resistance of S. aureus and CNS to β-lactam antibiotics (Trojan et al 2016). In a view of this, the emergence of methicillin resistance among Staphylococcus spp.…”