Antibiotic sensitivity pattern of diarrhoeal pathogens in under five children

Pervin, Mst Khashruba; Jhora, Sanya Tahmina; Paul, SK; Naher, Akhtarun

doi:10.3329/bmjk.v52i1-2.46148

Cited by 5 publications

(6 citation statements)

References 9 publications

(10 reference statements)

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“…However, lower rates of resistance were recorded in Macedonia 42 and Korea, 43 Pakistan 21 Bangladesh. 45 The main reason could be due to inappropriate use of antibiotics in Ethiopia. 46 …”

Section: Discussionmentioning

confidence: 99%

Campylobacter Gastroenteritis Among Under-Five Children in Southwest Ethiopia

Nigusu¹,

Abdissa²,

Tesfaw³

2022

IDR

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“…However, lower rates of resistance were recorded in Macedonia 42 and Korea, 43 Pakistan 21 Bangladesh. 45 The main reason could be due to inappropriate use of antibiotics in Ethiopia. 46 …”

Section: Discussionmentioning

confidence: 99%

Campylobacter Gastroenteritis Among Under-Five Children in Southwest Ethiopia

Nigusu¹,

Abdissa²,

Tesfaw³

2022

IDR

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“…Children are easily getting infected due to contaminated water and food as well as by contacting contaminated surfaces or animals that may carry certain bacteria like Salmonella spp. (16)(17)(18). Most positive cases were reported in summer-rainy seasons except in pus where the highest count was observed in late autumn.…”

Section: Discussionmentioning

confidence: 94%

“…In our study, E. coli bacteria was accounted very frequently (53.04% in urine, 36.28% in blood, and 54.55% in stool samples) which relates to other studies like 31.4% in Cameroonian towns (11), 34.1% in Namibia (12) and 86% in Nepal (10) were detected in the specimen of urine. Likewise, E. coli is the most common etiology of diarrhea among children in Bangladesh as well as in other developing countries resembling India (44.2%) and Sudan (53.8%) (17). Even in a blood specimen, the count of E. coli was the highest (n=41, 36.28%) where Simkhada et al in 2016 described Salmonella Paratyphi A (n=26, 54.17%) as the leading etiological agent in blood-borne infections and E. coli is only 6.25% (n=3) (22).…”

Section: Discussionmentioning

confidence: 99%

Characterization and Antibiotic Susceptibility of Bacteria Isolated from Clinical Specimens in Rajshahi, Bangladesh

Mondal

Islam

Zerin

2022

Int J Health Sci Res

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Infectious diseases caused by antibiotic-resistant infectious bacteria are a major threat to human survival and development. This is a retrospective study for a one-year period from January 2020 to December 2020 with a total of 1,112 urine, 318 blood, 167 stool, and 72 pus samples conducted in the Microbiology Laboratory of Rajshahi Metropolitan Hospital Ltd. and Diagnostic Center, Rajshahi, Bangladesh. Bacterial isolation, characterization, and antibiotic susceptibility were performed following the standard microbiological methods. Out of 1112 urine, 318 blood, 167 stool, and 72 pus specimens, bacteria were detected in 345 urine, 86 blood, 44 stool, and 50 pus specimens, respectively. Specimens from females (57.10%) were found more positive than those from males (42.90%) only in the case of urine samples. Among all the specimens, the highest number of infections was recorded in the age group 31–40, except in stool, where the highest positive cases were evidenced in the 0–10 age group. The greatest number of specimens was received, mostly in the summer and rainy seasons. However, E. coli bacteria were the most common among all the specimens excluding pus, where Staphylococcus aureus was the highest in number. Gram-positive and gram-negative bacteria showed higher sensitivity towards Cefepime (against pathogens of blood and stool samples) along with Imipenem, and Meropenem (pathogens of both urine and pus samples). A terrifying scenario was the high degree of resistance of those isolated bacteria towards the 3rd and 4th generation cephalosporin antibiotics. This study might be helpful for physicians to rationalize empiric treatment strategies and provide awareness among government authorities and the population. Key words: Bangladesh, Clinical specimens, Resistance, Retrospective, Sensitivity.

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“…In another study by Pervin et al ( 2019 ) in Bangladesh, out of two hundred seventeen (217) diarrhoeal stools, ninety-seven (97) bacterial isolates were isolated. Among ninety-seven (97) culture-positive cases, the percentages of E. coli , Shigella spp., and Salmonella spp.…”

Section: Discussionmentioning

confidence: 99%

“…were 51-52.58, 15-15.46, and 8-8.25%, respectively. Salmonella enteritidis was the utmost common serotype in Europe, Latin America, and Asia, accounting for 87%, 31%, and 38% of the clinical isolates, respectively (Pervin et al 2019 ). In another study, 126 Salmonella isolates dispersed among seven serotypes were shown to be multidrug-resistant, with high rates of AMR to lincomycin (100%), rifampicin (100%), sulfadiazine (93.7%), erythromycin (89.7%), ciprofloxacin (81.0%), and gentamicin (75.4%).…”

Section: Discussionmentioning

confidence: 99%

Identification and antibiotic pattern analysis of bacillary dysentery causing bacteria isolated from stool samples of infected patients

et al. 2022

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Bacillary dysentery is a type of dysentery and a severe form of shigellosis. This dysentery is usually restricted to Shigella infection, but Salmonella enterica and enteroinvasive Escherichia coli strains are also known as this infection’s causative agents. The emergence of drug-resistant, bacillary dysentery-causing pathogens is a global burden, especially for developing countries with poor hygienic environments. This study aimed to isolate, identify, and determine the drug-resistant pattern of bacillary dysentery-causing pathogens from the stool samples of the Kushtia region in Bangladesh. Hence, biochemical tests, serotyping, molecular identification, and antibiotic profiling were performed to characterize the pathogens. Among one hundred fifty (150) stool samples, 18 enteric bacterial pathogens were isolated and identified, where 12 were Shigella strains, 5 were S. enterica sub spp. enterica strains and one was the E.coli strain. Among 12 Shigella isolates, 8 were Shigella flexneri 2a serotypes, and 4 were Shigella sonnei Phage-II serotypes. Except for three Salmonella strains, all isolated strains were drug-resistant (83%), whereas 50% were multidrug-resistant (MDR), an alarming issue for public health. In antibiotic-wise analysis, the isolated pathogens showed the highest resistance against nalidixic acid (77.78%), followed by tetracycline (38.89%), kanamycin (38.89%), amoxicillin (27.78%), streptomycin (27.78%), cefepime (22.22%), ceftriaxone (22.22%), ampicillin (16.67%), ciprofloxacin (16.67%), and chloramphenicol (16.67%). The existence of MDR organisms that cause bacillary dysentery in the Kushtia area would warn the public to be more health conscious, and physicians would administer medications cautiously. The gradual growth of MDR pathogenic microorganisms needs immediate attention, and the discovery of effective medications must take precedence. Supplementary information The online version contains supplementary material available at 10.1007/s11756-022-01299-x.

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Antibiotic sensitivity pattern of diarrhoeal pathogens in under five children

Cited by 5 publications

References 9 publications

Campylobacter Gastroenteritis Among Under-Five Children in Southwest Ethiopia

Campylobacter Gastroenteritis Among Under-Five Children in Southwest Ethiopia

Characterization and Antibiotic Susceptibility of Bacteria Isolated from Clinical Specimens in Rajshahi, Bangladesh

Identification and antibiotic pattern analysis of bacillary dysentery causing bacteria isolated from stool samples of infected patients

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