Antibiotic Resistance Genes Dynamics at the Different Stages of the Biological Process in a Full-Scale Wastewater Treatment Plant

Zerva, Ioanna; Alexandropoulou, Ioanna; Panopoulou, Maria; Melidis, Paraschos; Ntougias, Spyridon

doi:10.3390/proceedings2110650

Cited by 5 publications

(9 citation statements)

References 18 publications

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“…The parallel increase of these two genes in the biomass despite ermF's notably lower presence in the effluent compared to sul1 may be due to previously observed differences in the genotypes of class 1 integrons and their incorporation of sul1 and ermF genes separately. 46 At the highest concentration of sulfamethoxazole (250 μg/L), both sul2 and oxa-1 genes were also observed to increase significantly (p < 0.028) compared to 50 μg/L, which suggests that a higher threshold of activation may cause the emergence of such genes. oxa-1 has previously been observed in gene cassettes with both sul1 and sul2, implying that there could be a basis for its enrichment by sulfamethoxazole at high concentrations.…”

Section: Environmental Science and Technologymentioning

confidence: 94%

Evaluating Antibiotic Resistance Gene Correlations with Antibiotic Exposure Conditions in Anaerobic Membrane Bioreactors

Zarei-Baygi

Harb

Wang

et al. 2019

Environ. Sci. Technol.

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Anaerobic membrane bioreactors (AnMBRs) are an emerging technology with potential to improve energy efficiency and effluent reuse in mainstream wastewater treatment. However, their contribution to the proliferation of contaminants of emerging concern, such as antibiotic resistance genes (ARGs), remains largely unknown. The purpose of this study was to determine the effect of select influent antibiotics at varying concentrations on the presence and abundance of ARGs in an AnMBR system and its effluent. Quantification of targeted ARGs revealed distinct profiles in biomass and effluent, with genes conferring resistance to different antibiotic classes dominating in biomass (macrolides) and effluent (sulfonamides). Effluent sul1 gene abundance was strongly correlated with abundance of intl1, signifying the potential importance of mobile genetic elements in ARG release from AnMBR systems. The addition of specific antibiotics also affected normalized abundances of their related ARGs, exemplifying the potential impact of selective pressures at both low (10 μg/L) and high (250 μg/L) influent antibiotic concentrations.

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Section: Environmental Science and Technologymentioning

confidence: 94%

Evaluating Antibiotic Resistance Gene Correlations with Antibiotic Exposure Conditions in Anaerobic Membrane Bioreactors

Zarei-Baygi

Harb

Wang

et al. 2019

Environ. Sci. Technol.

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“…Antibiotics and antibiotic resistance have been recognized by the World Health Organization (WHO) as the most critical public health issue of the 21st century. The main reservoirs of antibiotics and antibiotic resistance genes (ARGs) are wastewater treatment units, known as wastewater treatment plants (WWTPs), which originated from the presence of incompletely metabolized antibiotics in human excretions [84,92] being transferred to aquatic environments [93][94][95]. In nature, antibiotic resistance can spread either by antibiotics' distribution or by transferring ARGs between bacteria via conjugation, a microbial-specific process [78,92,[96][97][98].…”

Section: Water Quality and Use Of Nonconventional Water Resourcesmentioning

confidence: 99%

“…The main reservoirs of antibiotics and antibiotic resistance genes (ARGs) are wastewater treatment units, known as wastewater treatment plants (WWTPs), which originated from the presence of incompletely metabolized antibiotics in human excretions [84,92] being transferred to aquatic environments [93][94][95]. In nature, antibiotic resistance can spread either by antibiotics' distribution or by transferring ARGs between bacteria via conjugation, a microbial-specific process [78,92,[96][97][98]. Future work should focus on effective tertiary treatment methods and on the practices/mechanisms/processes driving ARGs' transfer source to the environment (aquatic and soil) and from the environment to animals and humans [84].…”

Section: Water Quality and Use Of Nonconventional Water Resourcesmentioning

confidence: 99%

Water Quality Focusing on the Hellenic World: From Ancient to Modern Times and the Future

Angelakιs

Dercas

Tzanakakis

2022

Water

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Water quality is a fundamental issue for the survival of a city, especially on dry land. In ancient times, water availability determined the location and size of villages and cities. Water supply and treatment methods were developed and perfected along with the evolution of urbanization. In Europe, after the fall of the Roman Empire, water supply and sewage systems went through fundamental changes. However, in medieval times, the lack of proper sanitation and low water quality increased the spreading and effects of epidemics. The importance of potable water quality was established during modern times. In Greece, the significance of water filtration and disinfection was not understood until the beginning of the 20th century. Moreover, the beneficial effects of water quality and sanitation on human health and especially on life expectancy are considered. In Greece and other countries, a dramatic increase in life expectancy mainly after the 2nd World War is probably due to the improvement of potable water quality and hygiene conditions. However, since the mid-20th century, new water quality issues have emerged, such as eutrophication, the improvement of water treatment technologies, as well as chemical and microbiological water pollution problems. This study, in addition to the historical evolution of water quality, highlights and discusses the current issues and challenges with regard to the management and protection of water quality, including global changes in population and urbanization, lack of infrastructure, use of nonconventional water resources, spreading of emerging pollutants and contaminants (e.g., antibiotics and microplastics), and climatic variability impacts. Against these, a review of the main proposed strategies and measures is presented and discussed to protect water quality and maintain water supplies for the future. Understanding the practices and solutions of the past provides a lens with which to view the present and future.

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“…The World Health Organization (WHO) recognizes antibiotics and antibiotic resistance, found in wastewater treatment units, as the most critical public health issue for the 21st century [90]. It is necessary to implement effective tertiary treatment methods [89][90][91][92][93][94], and elucidate the practices/mechanisms/processes driving Acquired Immunodeficiency Syndrome Resource Group (ARG) transfer sources to the environment (aquatic and soil), and from the environment to animals and humans [95][96][97], and of the role of other anthropogenic activities to antibiotics and ARG spreading [95]. The Coronavirus Disease 2019 (COVID-19) pandemic, despite the lack of a direct link with water resources, has revealed the severe weaknesses of modern societies regarding their abilities to withstand such extreme situations, and has raised awareness about the need for taking appropriate measurements to prepare our societies to withstand similar events in the future by strengthening their resilience.…”

Section: Public Health Issuesmentioning

confidence: 99%

Water Conflicts: From Ancient to Modern Times and in the Future

et al. 2021

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Since prehistoric times, water conflicts have occurred as a result of a wide range of tensions and/or violence, which have rarely taken the form of traditional warfare waged over water resources alone. Instead, water has historically been a (re)source of tension and a factor in conflicts that start for other reasons. In some cases, water was used directly as a weapon through its ability to cause damage through deprivation or erosion or water resources of enemy populations and their armies. However, water conflicts, both past and present, arise for several reasons; including territorial disputes, fight for resources, and strategic advantage. The main reasons of water conflicts are usually delimitation of boundaries, waterlogging (e.g., dams and lakes), diversion of rivers flow, running water, food, and political distresses. In recent decades, the number of human casualties caused by water conflicts is more than that of natural disasters, indicating the importance of emerging trends on water wars in the world. This paper presents arguments, fights, discourses, and conflicts around water from ancient times to the present. This diachronic survey attempts to provide water governance alternatives for the current and future.

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Antibiotic Resistance Genes Dynamics at the Different Stages of the Biological Process in a Full-Scale Wastewater Treatment Plant

Cited by 5 publications

References 18 publications

Evaluating Antibiotic Resistance Gene Correlations with Antibiotic Exposure Conditions in Anaerobic Membrane Bioreactors

Evaluating Antibiotic Resistance Gene Correlations with Antibiotic Exposure Conditions in Anaerobic Membrane Bioreactors

Water Quality Focusing on the Hellenic World: From Ancient to Modern Times and the Future

Water Conflicts: From Ancient to Modern Times and in the Future

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