Antibiotic prophylaxis for preventing burn wound infection

Surviving Sepsis Campaign: International Guidelines for Management of Sepsis and Septic Shock: 2016

“…Summarizing the evidence is challenging due to the diversity of the population. The quality of evidence was low for mortality in pancreatitis [122] and low for burns; therefore, we believe this recommendation is better addressed as a BPS, in which the alternative of administering antibiotics without indicators of infection is implausible [122][123][124]. Despite our recommendation against sustained systemic antimicrobial prophylaxis generally, brief antibiotic prophylaxis for specific invasive procedures may be appropriate.…”

“…Similarly, prolonged systemic antimicrobial prophylaxis has been used in the past for patients with severe burns. However, recent meta-analyses suggest questionable clinical benefit with this approach [123,124]. Current guidelines for burn management do not support sustained antimicrobial prophylaxis [101].…”

Bacteriological Profile and Antibacterial Sensitivity Patterns of Isolates among Burn Patients in Sulaimani City

“…Additionally, prolonged hospitalization and antibiotic therapy are risk factors for the development of methicillin-resistant Staphylococcus aureus (MRSA) colonization and infection. [5] Some strains of Pseudomonas aeruginosa (P. aeruginosa) and Acinetobacter now encountered in burn units are resistant to all the aforementioned antibiotic classes. Over the last 20 years, an increase in resistance of P. aeruginosa to reserve antibiotics such as ceftazidime, and a dramatic decrease in susceptibility of Acinetobacter spp.…”

Incidencia y factores de riesgo para bacteriemia en pacientes pediátricos con quemaduras en un Centro de Atención Especializado en México

“…En esta investigación, el promedio de tiempo entre la quemadura y el primer desbridamiento no fue diferente entre pacientes con y sin bacteriemia (2,2 días vs 2,5 días, p 0,55); sin embargo, en el análisis multivariado se observó que los pacientes con quemaduras > 20% de SCQ y de segundo En el presente estudio, 9,6% (n: 25) de los pacientes recibieron antimicrobianos profilácticos por vía sistémica antes de ingresar a la cohorte; sin embargo, de manera semejante a lo reportado por Barajas-Nava y cols. 16 , no se cuantificó diferencia en la ocurrencia de bacteriemia en pacientes con y sin antimicrobianos. Rosanova y cols.…”