At short term, in women with gestational diabetes requiring drug treatment, glibenclamide is clearly inferior to both insulin and metformin, while metformin (plus insulin when required) performs slightly better than insulin. According to these results, glibenclamide should not be used for the treatment of women with gestational diabetes if insulin or metformin is available.Systematic review registration NCT01998113.

Analysis 2.11. Comparison 2 Combination HT vs placebo in primary prevention, Outcome 11 Non-fatal MI: time on treatment..... Analysis 3.1. Comparison 3 Estrogen vs placebo in secondary prevention, Outcome 1 Death (all causes