Antibiotic misuse and the development of bacterial resistance: Are we losing the battle?

Al-Zidan, Radhwan Nidal; Abdulrazzaq, Ghayth M; Al-Shakarchi, Wejdan

doi:10.33899/iphr.2019.165710

Cited by 2 publications

(2 citation statements)

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“…Unfortunately, none of these attempts have been fully effective, and the concerns about the safety of prescription drugs have generated a growing desire for patients to use natural cholesterol-lowering products. Also, the scientists are searching for cholesterol-lowering and antiatherogenic activities of various plant products and their active ingredients in order to prevent or regulate atherosclerosis (5,6). Which is a complex inflammatory disease (7,8).…”

Section: Introductionmentioning

confidence: 99%

Effects of Hypericum perforatum on serum lipid vascular systems in mice

Hamed¹,

Abed²,

Almashhadany³

et al. 2022

IJVS

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Herbal products are increasingly used against lipid to attenuate its negative impact on vasculature system. However, there are uncertainty regarding the best administration approaches and preparation of herbal product to be used due to variation in absorption rate and extent with subsequent impaction on the lipid levels. The aim of the present study was comparing the pharmacological and analytical aspects of soaked versus powder form of Hypericum perforatum; a well-known anti-hyperlipidemic herbal product, using atorvastatin drug as a reference drug for comparison in addition to controlling groups (on/off lipid diet) handled as an additional control group. To conduct this research, the hyperlipidemia mice models were created by exposing the mice to a fatty diet and using H. perforatum and atorvastatin for evaluation. The plant extracts were also analyzed for active constituents. The results indicate that the plant analysis detected the presence of different antihyperlipidemic agents and the plant has effectively reduced plasma lipid parameters in exposed mice compared to control group; especially when taken forms of the plant was used. The study concluded that; soaked H. perforatum extract shown an effective reduction of lipid parameters and analysis of which revealed the presence of herbal active constituent which might be utilized in industrial pharmacy for new drug innovation.

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Section: Introductionmentioning

confidence: 99%

Effects of Hypericum perforatum on serum lipid vascular systems in mice

Hamed¹,

Abed²,

Almashhadany³

et al. 2022

IJVS

View full text Add to dashboard Cite

show abstract

“…Unfortunately, giving drugs to siblings or friends may increase the risk of developing a negative impact on health and wellbeing. For instance, there is an increase in developing antimicrobial resistance with the inappropriate use of antibiotics (Bergen et al 2015;Al-Zidan et al 2019;Nepal et al 2020).…”

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confidence: 99%

Exploring Household medicine waste in Iraq

Al-Jalehawi

Al-Zidan

Al-Mahmood

et al. 2022

Preprint

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Purpose: This study aims to explore household medicine wastes and their storage and disposal behavior in Iraq. This is a cross-sectional study conducted through an online questionnaire. Method: This is a cross-sectional study using an online form. The study collected data on the demographic of precipitants, the quantity and class of medication wastes, and the method of eliminating and discarding behaviors in Iraq. Results: A total of 742 house reports were included. There were 22,072 waste items in total. Paracetamol was the highest medication wasted (10.7%) product. The overall number of expired medications was 5332, with anti-infectives accounting for the biggest share (10.4 %). The majority of the expired drugs (78.1 %) were discarded in the garbage, whereas (61.7 %) of non-expired wastes are retained for future use. Among the various potential factors evaluated as a source of waste and expired drugs, 21.9 % were attributed to patient improvement. Regarding the storage sites, the refrigerator was the primary location. Conclusion: In conclusion, there is a large volume of domestic pharmaceutical waste which discarded in unplanned and harmful ways.

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Antibiotic misuse and the development of bacterial resistance: Are we losing the battle?

Cited by 2 publications

References 0 publications

Effects of Hypericum perforatum on serum lipid vascular systems in mice

Effects of Hypericum perforatum on serum lipid vascular systems in mice

Exploring Household medicine waste in Iraq

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