Antibacterial Values of Ethylene Glycol Monophenyl Ether (Phenoxetol)

Berry, H.

doi:10.1016/s0140-6736(00)42786-8

Cited by 28 publications

(12 citation statements)

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“…Berry (1944) found that its activity was greatest against Pseudomonas pyocyanea (aeruginosa) and that there was no loss of activity in the presence of 20% serum. In clinical trials, Gough et al (1944) reported that an aqueous solution of 2-2 % phenoxyethanol was effective for the treatment of burns and superficial wounds infected with Ps.…”

Section: Discussionmentioning

confidence: 99%

Sensitivity of urine-grown cells of Providencia stuartii to antiseptics.

Thomas¹,

Sykes²,

Stickler³

1978

J Clin Pathol

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Urine-grown cultures of 23 clinical isolates of Gram-negative bacteria having a range of minimum inhibitory concentration values for chorhexidine were challenged with various concentrations of this antiseptic. The results suggest that cells of Providencia stuartii, in particular, exhibit a considerable degree of resistance to chlorhexidine under these conditions, concentrations of up to 10 000--20 000 microgram/ml of urine being necessary to produce complete loss of viability of such cultures. Of the other two antiseptics tested, phenoxyethanol proved to be the more effective, the recommended use concentration of 2% v/v producing reductions in viable counts of greater than six logarithms in all the strains examined. It is suggested that phenoxyethanol may be a suitable alternative to the cationic agents for use in antiseptic policies for bladder management of urinary tract infections with Providencia stuartii.

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Section: Discussionmentioning

confidence: 99%

Sensitivity of urine-grown cells of Providencia stuartii to antiseptics.

Thomas¹,

Sykes²,

Stickler³

1978

J Clin Pathol

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“…The activity of this agent against Ps. aeruginosa has been known for many years and it is particularly interesting that it seems to be more active against this drug‐resistant species than against Gram‐positive cocci (Berry 1944). An examination of the sensitivity of urinary isolates of Ps.…”

Section: Alternatives To Chlorhexidine In Catheter Managementmentioning

confidence: 99%

Susceptibility of antibiotic-resistant Gram-negative bacteria to biocides: a perspective from the study of catheter biofilms

Stickler

2002

Journal of Applied Microbiology

104

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“…The effectiveness of this agent against P. aeruginosa has been known for some time and it appears to be more active against this species than against E. coli and even Gram-positive organisms (Berry, 1944;Gough, Berry and Still, 1944). Thomas et al, (1978) also found that it was bactericidal against urine grown cultures of P. aeruginosa, Proteus mirabilis and Providencia stuartii known to be resistant to be cationic antiseptics.…”

Section: Figmentioning

confidence: 99%

Antiseptic and antibiotic resistance in Gram-negative bacteria causing urinary tract infection in spinal cord injured patients

1981

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Abstract. Fifty-seven isolates of Gram-negative bacterial species from urinary tract infections in spinal cord injured patients were tested for their sensitivity to chlorhexidine, cetrimide, glutaraldehyde, phenyl mercuric nitrate (PMN), a phenolic disinfectant (Hycolin) and a proprietary antiseptic containing a mixture of picloxydine, octylphenoxy polyethoxyethanol and benzalkonium chloride (Resiguard). None of the isolates were resistant to glutaraldehyde, Hycolin or PMN but a substantial percentage were resistant to chlorhexidine (44 per cent), cetrimide (26 per cent) and Resiguard (42 per cent). The resistant organisms were members of the genera Proteus, Providencia and Pseudomonas and they were also generally resistant to five, six or seven antibiotics. Significant correlations were observed between multiplicity of antibiotic resistance and the minimum inhibitory concentrations of the three cationic antiseptics. It is suggested that an antiseptic policy for the bladder management of spinal cord injured patients that relies on the extensive use of cationic agents might lead to the selection of a flora of notoriously drug-resistant species.

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Antibacterial Values of Ethylene Glycol Monophenyl Ether (Phenoxetol)

Cited by 28 publications

References 0 publications

Sensitivity of urine-grown cells of Providencia stuartii to antiseptics.

Sensitivity of urine-grown cells of Providencia stuartii to antiseptics.

Susceptibility of antibiotic-resistant Gram-negative bacteria to biocides: a perspective from the study of catheter biofilms

Antiseptic and antibiotic resistance in Gram-negative bacteria causing urinary tract infection in spinal cord injured patients

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