Antibacterial Potential of Capparis spinosa and Capparis decidua Extracts

Abstract

Capparis spinosa and C. decidua are indigenous medicinal plants of Pakistan which are rich in antioxidant compounds. In present investigation, the aqueous menthanolic, ethanolic and acetone extracts of stem bark, shoot, fruit, flower and roots of both species were investigated for their antimicrobial potential in comparison with amoxicillin and ciprofloxacin (control). The effect of these extracts was evaluated on the growth of four bacteria i.e., Staphylococcus aureus, Escherichia coli, Bacillus subtilis and Pasteurella multocida using disc diffusion and minimum inhibitory concentration (MIC) assays. After comparing all extracts, it was found that methanolic extracts of selected parts of both species significantly reduced the growth of all four bacteria although different extracts expressed varying efficacy in reducing bacterial growth. It was further noted that S. aureus growth was mainly inhibited by methanolic extracts of C. decidua flowers and roots (GIZ: 26.5 and 26.4 mm, respectively), E. coli population was effectively reduced by methanolic extracts of C. decidua roots and shoots (GIZ: 29.1 26.7 mm, respectively) while B. subtilis growth was inhibited maximally by methanolic extracts of C. spinosa stem bark and C. decidua fruits (GIZ: 26.8 and 26.8, respectively). Moreover, methanolic extract of C. decidua root markedly inhibited the growth of P. multocida (25.7 mm). On the basis of above mentioned findings, it can safely be concluded that C. decidua possess higher antimicrobial potential than C. spinosa and these can be used as natural antibacterial agent.

Metabolomic Profiling and Antioxidant, Anticancer and Antimicrobial Activities of Hyphaene thebaica

“…Besides their radical scavenging activity, doum palm extracts showed antibacterial efficacy. Bacterial strains differ in their responses to the plant extracts depending on the strain, nature of the cell wall, plant part, extraction method and extraction solvent [38]. In this study, E. coli (Gram-negative) was more sensitive to leaves and fruits methanol extracts followed by S. aureus and B. subtilis (Gram-positive), respectively.…”

“…In this study, E. coli (Gram-negative) was more sensitive to leaves and fruits methanol extracts followed by S. aureus and B. subtilis (Gram-positive), respectively. Accordingly, previous studies have demonstrated higher sensitivity of E. coli than S. aureus and B. subtilis towards methanolic flower extract of Capparis spinosa and root extract of C. decidua [38]. The antimicrobial activity of doum palm was attributted to its rich content of secondary metabolites.…”

“…The antimicrobial activity of doum palm was attributted to its rich content of secondary metabolites. The correlation between the plant content of secondary metabolites, such as anthocyanins, saponins, phenolics, flavonoids and tannins, and the antimicrobial potentiality was reported [38,39]. The individual polyphenolic compounds profiled in HPLC were well-known as antimicrobial agents against wide spectrum of Gram-positive and negative bacteria [40,41].…”

Chemical composition and antibacterial activities of Capparis spinosa essential oils from Algeria

“…Capparis spinosa leaves from Egypt extracted with various solvents showed significant antibacterial activities against Klebsiella pneumonia and Enterococcus faecalis (Sherif et al 2013). Aqueous extracts of the roots and fruits of C. spinosa showed potent antimicrobial activity against a wide range of microorganisms (Mahboubi and Mahboubi 2014;Gull et al 2015). A study by Al-Azawi et al (2018) showed that methanolic extract of C. spinosa leaves had potent antibacterial activity, particularly against S. aureus, K. pneumonia, and E. coli.…”

Optimized Biosynthesis and Antifungal Activity of Osmanthus fragrans Leaf Extract-mediated Silver Nanoparticles

“…Exploration is imperative for new agents with low toxicity and high efficiency to replace existing highly-toxic pesticides. Accordingly, more and more attention has been paid to research on silver nanoparticles as antimicrobial agents against organisms that include bacteria (Li et al, 2010;Li et al, 2011), fungi (Jo et al, 2009;Gull et al, 2015), and viruses (Elechiguerra et al, 2005;Lara et al, 2010).…”