Antibacterial poly(vinyl alcohol) film containing silver nanoparticles: Preparation and characterization

Galya, Tsermaa; Sedlařík, Vladimír; Kuřitka, Ivo; Novotný, Radko; Sedlaříková, Jana; Sáha, Petr

doi:10.1002/app.28908

Cited by 101 publications

(58 citation statements)

References 24 publications

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“…The antimicrobial properties of PVP-CMC and PVP-CMC-BA hydrogels were investigated by agar diffusion method (30,31). Antimicrobial characteristics of these hydrogels were examined on the basis of the dimension of inhibition zone generated in the presence and absence of pathogenic bacteria like Escherichia coli, Staphylococcus aureus, Klebsiella pneumoniae, and Pseudomonas aeruginosa and fungi like Candida albicans and Candida parapsi-losis.TYve antibacterial assay was conducted in a sterile nutrient agar (2%) medium that was inoculated with the aforementioned bacterial strains under aseptic condition.…”

Section: Assay Of Antimicrobial Propertymentioning

confidence: 99%

Development and Characterization of Novel Medicated Hydrogels for Wound Dressing

Roy¹,

Saha²,

Kitano³

et al. 2010

Soft Materials

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□ The medicated hydrogels were prepared aseptically under moist heat treatment using polyvinylpyrrolidone (PVP), sodium-carboxymethylcellulose (CMC), polyethyleneglycol (PEG), agar, glycerin and/or boric acid (BA) and designated as PVP-CMC and PVP-CMC-BA. The aim of this study was to develop some medicinal values-based hydrogels. BA was used to build up the medicinal values (antiseptic and antimicrobial properties) within the hydrogels. Optical images, scanning electron microscopy (SEM), and Fourier transform infrared (FTIR) spectroscopy of the hydrogels indicated that boric acid is uniformly dispersed within the cross-linked hydrogel network that may heal and protect the wounds from infections/sepsis. Swelling study in presence of water and physiological saline solution confirmed its reasonable absorption capacity. The rheological properties and mechanical properties demonstrated that the boric acid incorporated hydrogels are quite flexible. Assessment of antimicrobial property study proves that PVP-CMC-BA (3 % BA) has strong infection protection capacity.Keywords Boric acid, Hydrogels, Swelling, Viscoelastic properties, Wound dressing INTRODUCTIONThe medicated hydrogels are the hydrogels that possess some medicinal value within them. They are cross-linked polymeric gels that have water-holding and nonadhering properties. Hydrogels can be prepared with monomers, prepolymers, or existing hydrophilic polymers as starting materials. They are generally specified by two component systems. One of the components is hydrophilic, which has water insoluble three-dimensional polymer networks, and the second component is water. They may swell in water up to a large extent and reach the equilibrium state while retaining their original shape (1).In fact, a hydrogel is considered as a kind of cheap, effective, convenient material for wound dressing, due to its good biocompatibility, water absorption ability, moisture retention, and ventilating capacity (2). They are closely resembled to living tissue in their physical properties because of their relatively high water content as well as soft and rubbery consistency (3). Numerous research studies have established that a moist wound environment is most favorable for healing (4). Hydrogel wound burn dressings were first invented by Rosiak et al. in 1989, which have many interesting properties, such as immediate pain control, easy replacement, transparency, absorption, prevention of loss of body fluids, barrier against bacteria, good adhesion, easy handling, oxygen permeability, control of drug dosage, and so on (3,5,6).The hydrogel dressings are usually directly applied to the wounds, thus the biocompatibility and non-toxicity factors are required to be taken into consideration. Polyvinylpyrrolidone (PVP) is a well-known polymer with good biocompatibility; hence, this polymer can be used as one of the main components of pseudo hydrogel preparation for temporary skin covers or wound dressings (6, 7). PVP is used in production of medicines and serves as blood substitute and blood d...

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Section: Assay Of Antimicrobial Propertymentioning

confidence: 99%

Development and Characterization of Novel Medicated Hydrogels for Wound Dressing

Roy¹,

Saha²,

Kitano³

et al. 2010

Soft Materials

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“…Recently, many efforts have focused on the design and fabrication of polymer/metal nanoparticle (like silver) complexes due to their remarkable electronic, magnetic, catalytic, thermal and optical properties [29]. Basic principle for the fabrication of silver nanoparticles (AgNPs) involves the reduction of metal salts like silver nitrate (AgNO 3 ) in an appropriate medium using various reducing agents and surfactants to produce colloidal suspensions integrated by nanoparticles [29][30][31][32]. Unlike elemental silver, silver salts easily dissolve in water, and they increase the rate of Ag + ion formation over that from elemental silver.…”

Section: -15mentioning

confidence: 99%

Multifunctional e-spun colloidal nanofiber structures from various dispersed blends of PVA/ODA-MMT with PVP/ODA-MMT, poly(VP-alt-MA) and AgNPs incorporated polymer complexes as electro-active platforms

Bunyatova¹,

Rzayev²,

Şimşek³

2016

Express Polym. Lett.

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“…The antimicrobial properties of polymer sheet covers (BF and BL) were investigated by the agar diffusion method [20,[32][33][34]. Antimicrobial characteristics of these polymer sheets were examined on the basis of the dimension of the inhibition zone generated in the presence of pathogenic bacteria like Escherichia coli (E. coli) and Staphylococcus aureus (S. aur).…”

Section: Antimicrobial Propertymentioning

confidence: 99%

Significant Characteristics of Medical-Grade Polymer Sheets and their Efficiency in Protecting Hydrogel Wound Dressings: A Soft Polymeric Biomaterial

Roy

Saha

Kitano

et al. 2012

International Journal of Polymeric Materials

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Hydrogel dressings are soft biomaterials that need protection from external influences. Polymer sheets such as breathable film (BF) or breathable laminate (BL) were characterized in respect of water vapor transmission, water contact angle, microbial penetrability, and antimicrobial property to protect hydrogel dressings. The mechanical property and water retention ability of hydogels PVP-CMC and PVP-CMC-BA with and without BF and BL have been examined. Hydrogels covered with either BF or BL show better mechanical flexibility; however, their water retention capacity increases reasonably. The determined efficient properties of polymer sheets established that BF is better than BL as a protective sheet cover for hydrogel dressings.

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Antibacterial poly(vinyl alcohol) film containing silver nanoparticles: Preparation and characterization

Cited by 101 publications

References 24 publications

Development and Characterization of Novel Medicated Hydrogels for Wound Dressing

Development and Characterization of Novel Medicated Hydrogels for Wound Dressing

Multifunctional e-spun colloidal nanofiber structures from various dispersed blends of PVA/ODA-MMT with PVP/ODA-MMT, poly(VP-alt-MA) and AgNPs incorporated polymer complexes as electro-active platforms

Significant Characteristics of Medical-Grade Polymer Sheets and their Efficiency in Protecting Hydrogel Wound Dressings: A Soft Polymeric Biomaterial

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