Antibacterial effect of silver nanoparticles and capsaicin against MDR-ESBL producing Escherichia coli: An in vitro study

Kar, Debasish; Bandyopadhyay, Samiran; Dimri, Umesh; Mondal, Deba Brata; Nanda, Pramod Kumar; Das, Anubrata; Batabyal, Subhasish; Dandapat, Premanshu; Bandyopadhyay, S.

doi:10.1016/s2222-1808(16)61135-0

Cited by 36 publications

(21 citation statements)

References 30 publications

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“…The small particle size enables AgNPs to adhere to the cell wall and penetrate into the bacteria cell easily, which in turn improves their antimicrobial activity against bacteria. The antimicrobial effects of AgNPs against multidrug resistant bacteria have been studied by many researchers and it was proved that AgNPs are effective against multidrug resistant bacteria such as multidrug resistant E. coli ( Paredes et al, 2014 ; Kar et al, 2016 ), multidrug resistant strain of Pseudomonas aeruginosa ( Durairaj et al, 2012 ), methicillin-resistant Staphylococcus aureus (MRSA) ( Paredes et al, 2014 ; Yuan et al, 2017 ), and extended-spectrum β-lactam (ESBL) producing bacteria ( Doudi et al, 2013 ; Subashini et al, 2014 ).…”

Section: Resultsmentioning

confidence: 99%

In Vitro Antimicrobial Activity of Green Synthesized Silver Nanoparticles Against Selected Gram-negative Foodborne Pathogens

et al. 2018

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Silver nanoparticles (AgNPs) used in this study were synthesized using pu-erh tea leaves extract with particle size of 4.06 nm. The antibacterial activity of green synthesized AgNPs against a diverse range of Gram-negative foodborne pathogens was determined using disk diffusion method, resazurin microtitre-plate assay (minimum inhibitory concentration, MIC), and minimum bactericidal concentration test (MBC). The MIC and MBC of AgNPs against Escherichia coli, Klebsiella pneumoniae, Salmonella Typhimurium, and Salmonella Enteritidis were 7.8, 3.9, 3.9, 3.9 and 7.8, 3.9, 7.8, 3.9 μg/mL, respectively. Time-kill curves were used to evaluate the concentration between MIC and bactericidal activity of AgNPs at concentrations ranging from 0×MIC to 8×MIC. The killing activity of AgNPs was fast acting against all the Gram-negative bacteria tested; the reduction in the number of CFU mL-1 was >3 Log10 units (99.9%) in 1–2 h. This study indicates that AgNPs exhibit a strong antimicrobial activity and thus might be developed as a new type of antimicrobial agents for the treatment of bacterial infection including multidrug resistant bacterial infection.

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Section: Resultsmentioning

confidence: 99%

In Vitro Antimicrobial Activity of Green Synthesized Silver Nanoparticles Against Selected Gram-negative Foodborne Pathogens

et al. 2018

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“…Co-administration of NPs along with antibiotic inhibited protein translation in S. aureus strains. In an interesting study, Kar et al ( 290 ) studied the antibacterial property of AgNPs and capsaicin against MDR and ESBL producing E. coli of bovine and poultry origin and postulated that AgNPs and capsaicin could effectively be used to inhibit the growth of MDR-ESBL producing E. coli . Alizadeh et al ( 291 ) studied the positive antimicrobial effect of AgNPs against B. abortus .…”

Section: Nanoparticles (Nps)mentioning

confidence: 99%

Antimicrobial Resistance: Its Surveillance, Impact, and Alternative Management Strategies in Dairy Animals

et al. 2018

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Antimicrobial resistance (AMR), one among the most common priority areas identified by both national and international agencies, is mushrooming as a silent pandemic. The advancement in public health care through introduction of antibiotics against infectious agents is now being threatened by global development of multidrug-resistant strains. These strains are product of both continuous evolution and un-checked antimicrobial usage (AMU). Though antibiotic application in livestock has largely contributed toward health and productivity, it has also played significant role in evolution of resistant strains. Although, a significant emphasis has been given to AMR in humans, trends in animals, on other hand, are not much emphasized. Dairy farming involves surplus use of antibiotics as prophylactic and growth promoting agents. This non-therapeutic application of antibiotics, their dosage, and withdrawal period needs to be re-evaluated and rationally defined. A dairy animal also poses a serious risk of transmission of resistant strains to humans and environment. Outlining the scope of the problem is necessary for formulating and monitoring an active response to AMR. Effective and commendably connected surveillance programs at multidisciplinary level can contribute to better understand and minimize the emergence of resistance. Besides, it requires a renewed emphasis on investments into research for finding alternate, safe, cost effective, and innovative strategies, parallel to discovery of new antibiotics. Nevertheless, numerous direct or indirect novel approaches based on host–microbial interaction and molecular mechanisms of pathogens are also being developed and corroborated by researchers to combat the threat of resistance. This review places a concerted effort to club the current outline of AMU and AMR in dairy animals; ongoing global surveillance and monitoring programs; its impact at animal human interface; and strategies for combating resistance with an extensive overview on possible alternates to current day antibiotics that could be implemented in livestock sector.

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“…The occurrence of cancer is also increasing steadily. Misuse or overuse of antibiotics has led to the development of resistance in the microorganisms and even second line of treatment has become questionable [20]. The cells have antioxidant mechanism to overcome the free radical generation but when this balance is shaken with over production of free radicals and reactive oxygen species, stress condition occurs which leads to many diseases and disorders [16].…”

Section: Introductionmentioning

confidence: 99%

Biosynthesis of silver nanoparticles formation from Caesalpinia pulcherrima stem metabolites and their broad spectrum biological activities

Moteriya

Chanda

2018

Journal of Genetic Engineering and Biotechnology

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The present work illustrates eco-friendly, rapid and cost effective method of AgNPs synthesis using C. pulcherrima stem extract. Initially, various physico chemical factors were optimized. Characterization was done by different spectroscopic and microscopic analysis. AgNPs were spherical in shape with an average size of 8 nm. AgNPs showed good synergistic antimicrobial, antibiofilm and antioxidant activity. The cytotoxicity effect against HeLa cancer cell line was dose dependent while genotoxic study revealed the non toxic nature of AgNPs at lower concentration. The results suggest that AgNPs from C. pulcherrima stem extract have great potential in biomedical applications.

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Antibacterial effect of silver nanoparticles and capsaicin against MDR-ESBL producing Escherichia coli: An in vitro study

Cited by 36 publications

References 30 publications

In Vitro Antimicrobial Activity of Green Synthesized Silver Nanoparticles Against Selected Gram-negative Foodborne Pathogens

In Vitro Antimicrobial Activity of Green Synthesized Silver Nanoparticles Against Selected Gram-negative Foodborne Pathogens

Antimicrobial Resistance: Its Surveillance, Impact, and Alternative Management Strategies in Dairy Animals

Biosynthesis of silver nanoparticles formation from Caesalpinia pulcherrima stem metabolites and their broad spectrum biological activities

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