Antibacterial and In Vitro Growth Inhibition Study of Struvite Urinary Stones Using Oxalis corniculata Linn. Leaf Extract and its Biofabricated Silver Nanoparticles

Das, Purnima; Kumar, K. Sathesh; Nambiraj, Arunai; Awasthi, Rajendra; Dua, Kamal; Himaja, M.

doi:10.2174/1872211312666180723160624

Cited by 13 publications

(9 citation statements)

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“…In their analysis, the results of agar well diffusion and microdilution tests were not consistent [63]. In a study by Das et al the antibacterial activity of O. corniculata aqueous extract as biofabricated silver nanoparticles (AgNPs) against UTI-causing bacteria was many times higher than normal extract [64]. Rahman et al found that methanolic extract had more bacteriostatic activity against Gram-positive and Gram-negative bacteria than ethanolic extract, but the bacteriostatic activity of both extracts was lower than that of the cephachlore antibiotic [65].…”

Section: Discussionmentioning

confidence: 95%

Antibacterial Potency of Medicinal Plants including Artemisia annua and Oxalis corniculata against Multi-Drug Resistance E. coil

Golbarg

Moghaddam

2021

BioMed Research International

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Antibacterial activity of ethanolic and aqueous extracts of two medicinal plants including Oxalis corniculata (EtOc, AqOc) and Artemisia annua (EtAa, AqAa) as well as A. annua essential oil (EoAa) was investigated on multi-drug resistance (MDR) E. coli. Microdilution and agar well diffusion methods were used to determine the minimum inhibitory concentration (MIC), minimum bactericidal concentration (MBC) as well as the inhibition zone. The phytconstituents of these products were analyzed using Reverse-phase High- performance liquid chromatography (RP-HPLC) and gas chromatography-mass spectrometry (GC-mass). The order of bacteriostatic and bacteriocide rate of the products can be shown as follows: EoAa>AqOc>EtAa = AqAa>EtOc, but the bactericidal effect of A. annua extracts is higher than of O. corniculata based on the MIC/MBC ratio and the order is as follows: EoAa>EtAa = AqAa>EtOc>AqOc. The most potent product, i.e. EoAa with a 56.7% inhibition of all isolates, has the potential to substitute 13 used antibiotics including oxacillin, amoxicillin, ampicillin, amoxicillin-clavulanic acid, tetracycline, streptomycin, ciprofloxacin, ceftriaxone, cefazolin, cefuroxime, cefotaxime, ceftazidime and cefixime (P <0.05). Different terpenoids were detected and measured in EoAa and catechin flavonoids in extracts of both plants, quercetin in extracts of O. corniculata but it was only possible to detect chlorogenic acid polyphenol in AqAa. Due to the antibacterial activities of the studied products, more effective than some antibiotics and their edible consumption, these products can be suggested as an alternative to some antibiotics and food preservatives to fight against MDR E. coli.

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Section: Discussionmentioning

confidence: 95%

Antibacterial Potency of Medicinal Plants including Artemisia annua and Oxalis corniculata against Multi-Drug Resistance E. coil

Golbarg

Moghaddam

2021

BioMed Research International

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“…The EDAX analysis shows the elements outline as well as the amount of biosynthesized CuNPs Copper oxide nanoparticles are formed (Fig. 7) (Das et al, 2018).…”

Section: Edax Analysismentioning

confidence: 99%

Biogenesis of Metal Nanoparticles and its Potential Targeted Drug Delivery Systems for Urolithiasis

F.¹,

A.²,

Vidhya³

et al. 2022

IJZI

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Urinary stones are a biggest issue that people experience worldwide. Urinary tract infections that lead to struvite urinary stones are the result of improper organ function, particularly kidney. The present study concentrated on an economical and environmentally friendly method for producing copper nanoparticles utilizing Eclipta prostrata leaves extract as a reducing and capping agent. UV-Visible spectroscopy shows SPR band at 256 nm which was used to validate the synthesis of copper nanoparticles. According to FT-IR Spectroscopic investigations, phytoconstituents have a major role in the reduction and capping of copper nanoparticles. E. prostrata mediated copper nanoparticles were crystallized and had a spherical shape, according to XRD and SEM. The EDX analysis showed the elemental composition and the amount of copper nanoparticles. The copper nanoparticles mediated by E. prostrata were found to have an inhibitory efficiency of 88.3% showing that they were an effective inhibitor for the struvite crystals. According to FT-IR spectra the shifting of the band confirmed that the phytocomponents present in E. prostrata leaves extract is responsible for anti-urolithiatic activity.

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“…Saleh et al [126] formulated and investigated the mechanisms of antimicrobial action of two different types of metallic NPs, i.e., Ag-based and titanium dioxide-based NPs, against Proteus vulgaris and Proteus mirabilis, reporting that both kinds of NPs inhibited the microbial species via downregulation of fliL gene expression directly associated with blockade of the movement of the Proteus species. Similarly, Das et al [127] created Ag NPs loaded with the extract of Oxalis corniculata and observed that compared with pure extract, extract-based Ag NPs exhibited significantly higher antimicrobial activities against both Gram-positive and Gram-negative bacterial strains, the leading cause of UTIs. In addition, the authors also reported that the formulations allowed for significantly higher kidney stone dissolution, an effect further increased in the presence of Ag NPs.…”

Section: Silver-based Npsmentioning

confidence: 99%

Nanomaterials for the Diagnosis and Treatment of Urinary Tract Infections

et al. 2021

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The diagnosis and treatment of urinary tract infections (UTIs) remain challenging due to the lack of convenient assessment techniques and to the resistance to conventional antimicrobial therapy, showing the need for novel approaches to address such problems. In this regard, nanotechnology has a strong potential for both the diagnosis and therapy of UTIs via controlled delivery of antimicrobials upon stable, effective and sustained drug release. On one side, nanoscience allowed the production of various nanomaterial-based evaluation tools as precise, effective, and rapid procedures for the identification of UTIs. On the other side, nanotechnology brought tremendous breakthroughs for the treatment of UTIs based on the use of metallic nanoparticles (NPs) for instance, owing to the antimicrobial properties of metals, or of surface-tailored nanocarriers, allowing to overcome multidrug-resistance and prevent biofilm formation via targeted drug delivery to desired sites of action and preventing the development of cytotoxic processes in healthy cells. The goal of the current study is therefore to present the newest developments for the diagnosis and treatment of UTIs based on nanotechnology procedures in relation to the currently available techniques.

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Antibacterial and In Vitro Growth Inhibition Study of Struvite Urinary Stones Using Oxalis corniculata Linn. Leaf Extract and its Biofabricated Silver Nanoparticles

Cited by 13 publications

References 0 publications

Antibacterial Potency of Medicinal Plants including Artemisia annua and Oxalis corniculata against Multi-Drug Resistance E. coil

Antibacterial Potency of Medicinal Plants including Artemisia annua and Oxalis corniculata against Multi-Drug Resistance E. coil

Biogenesis of Metal Nanoparticles and its Potential Targeted Drug Delivery Systems for Urolithiasis

Nanomaterials for the Diagnosis and Treatment of Urinary Tract Infections

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