2020
DOI: 10.1111/lam.13275
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Antibacterial activity of viable and heat‐killed probiotic strains against oral pathogens

Abstract: Probiotics can stabilize gut flora, regulate intestinal immunity and protect the host from enteric diseases; however, their roles in oral health have received little attention compared to their roles in gut health. Nowadays, the prevalence of sugar‐sweetened foods and abuse of antibiotics contribute towards dysbiosis of oral microbiota and drug resistance development in oral pathogens, resulting in various intractable oral diseases. We screened the antibacterial activities of viable and heat‐killed probiotic s… Show more

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Cited by 34 publications
(37 citation statements)
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References 32 publications
(35 reference statements)
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“…L. kunkeei, has marked antibacterial attributes that make it a highly effective natural biocontrol system. Rising drug resistance coupled with an absence of new antibiotics has made probiotic candidates with antipathogenic activities an attractive therapeutic option, especially since they are free of side effects and have an overall natural appeal [66]. Subtractive screenings have yet to identify a super bacterium having all possible beneficial attributes; therefore, statistical tools such as PCA must still be used to sift through preliminary screening data to identify strains with desirable phenotypes [67].…”
Section: Discussionmentioning
confidence: 99%
“…L. kunkeei, has marked antibacterial attributes that make it a highly effective natural biocontrol system. Rising drug resistance coupled with an absence of new antibiotics has made probiotic candidates with antipathogenic activities an attractive therapeutic option, especially since they are free of side effects and have an overall natural appeal [66]. Subtractive screenings have yet to identify a super bacterium having all possible beneficial attributes; therefore, statistical tools such as PCA must still be used to sift through preliminary screening data to identify strains with desirable phenotypes [67].…”
Section: Discussionmentioning
confidence: 99%
“…Each study that met the inclusion criteria was analyzed to identify prebiotic compounds or probiotic strains and their effects on the oral microbial flora or immunological markers involved in mental disorders. Three distinct effects on oral dysbiosis associated with mental disorders emerged: modulation of the oral microbiome [ 38 , 39 , 40 , 41 , 42 , 43 , 44 , 45 , 46 , 47 , 48 , 49 , 50 , 51 ], antimicrobial activity [ 52 , 53 , 54 , 55 , 56 , 57 , 58 , 59 , 60 , 61 , 62 , 63 , 64 , 65 , 66 , 67 , 68 , 69 ], and modulation of immunological or inflammatory factors [ 43 , 44 , 46 , 56 , 70 , 71 , 72 , 73 , 74 , 75 ].…”
Section: Resultsmentioning
confidence: 99%
“…Autoaggregation ability of 14 Lactobacillus strains was assessed by phase separation method as previously described [24] with minor modifications. Each of the 14 Lactobacillus strains was grown at 37˚C in MRS broth to stationary phage.…”
Section: Autoaggregation Assaymentioning
confidence: 99%
“…Human-origin Lactobacillus is a preferable source of probiotic bacteria, and Lactobacillus isolates from human oral cavity [8] [14], breast milk [15] [16], stomach [17], feces or intestinal tract [18] [19] [20] have been studied on their probiotic characteristics. Lactobacillus plays an important role in maintaining the health of human vagina [4] [6].…”
Section: Introductionmentioning
confidence: 99%