“…These findings do not correlate with the observations of previous screenings of medicinal plants for antimicrobial activity, where most of the active plant extracts showed activity against Gram-positive strains only [56][57][58][59] . Because Gram-negative organisms were reported to be less susceptible to the action of antibacterials, since they possess an outer membrane surrounding the cell wall, which restricts diffusion of hydrophobic compounds through its lipopolysaccharide covering [60][61][62][63][64][65][66][67] . Besides the difference in sensitivity might be ascribed to the difference in morphological constitutions between Gram-positive and Gram-negative organisms.…”