Antibacterial Activity of Pulicaria odora Leaf Phenolics Collected in Algeria

Abstract

Background: Pulicaria is a genus of the Asteraceae family, tribe Inuleae, containing 100 species with a distribution from Europe to North Africa to Asia. Objective: In this work, the study is focused on the difference in phytochemical and antibacterial activity of Pulicaria odora harvested in two regions of northern Algeria. Methods: Two maceration extraction methods were used; at room temperature and bath shaker at 37 °C. Total phenolics and flavonoids were carried out using folin ciocalteu and aluminium chloride methods, respectively. Antibacterial activity was evaluated by agar diffusion method on four bacterial strains Listeria innocua, Staphylococcus aureus, Escherichia coli, Pseudomonas aeruginosa. Results: The results found showed that the highest total polyphenol content was 271,8 ± 22,52 mg gallic acid equivalent / g dry matter (mg GAE/g of DM); the best flavonoid content is 51,53 ± 4,42 mg quercetin equivalent / g of dry matter (mg QE/g of DM) harvested in Bejaia. The best level of total polyphenols and flavonoids from the plant harvested in the region of Tizi-Ouzou are 218,23 ± 12.33 mg GAE / g of DM, 54,15 ± 5,98 mg QE / g DM respectively. The two phenolic extracts obtained by the two solvents at a concentration of 70% are more active against S. aureus (17.66 mm for the sample of Bejaia at the concentration 1mg /20µL), while a moderate sensitivity is recorded against other strains for the two samples. Conclusion: Pulicaria odora leaf extract is strong against bacterial infection and can be used as medicinal remedy and in food industry.

Phytochemical analysis and biological investigation of Cheilanthes tenuifolia (Burm.f.) Swartz

“…Infectious diseases due to microbial attacks (e.g., bacteria, fungi, viruses, and parasites) in humans are a common consequence in the world. Among the wide variety of natural products, plants are considered major sources of antimicrobial agents ( Touati et al, 2018 ). The species of the Pteridaceae family are known for their diverse bioactivities, including antioxidant, anti-inflammatory, antimicrobial, anti-cancer, antidiabetic, and neurobiological properties ( Baskaran et al, 2018 ).…”

Bioactive Potential of Baby Corn Silk: In-Vitro Evaluation of Antioxidant, Antimicrobial, Anti-diabetic, and Anti-gout Activities

“…The search for compounds displaying potent antimicrobial properties has remained a pursued area of investigation, aimed at mitigating the threat posed by infections arising from pathogenic microorganisms such as bacteria, fungi, viruses, and parasites that affect human health. Plant extracts continue to stand out as source of numerous therapeutic substances, including antimicrobial agents, which play a pivotal role in addressing infectious diseases [19][20]. Plants possess a diverse range of secondary metabolites, including tannins, alkaloids, phenolic compounds, and avonoids, which have demonstrated in-vitro antimicrobial potential [21][22].…”