Antibacterial Activity of Pipemidic Acid ions-MgFeAl Layered Double Hydroxide Hybrid Against E. coli and S. typhi

Abstract

An anion exchange process was used to prepare pipemidic acid-MgFeAl composite from MgFeAl-Cl layered double hydroxide as inorganic matrix. The obtained hybrid material contains pipemidic acid anions as well as, in a less extent; carbonate and chloride species in its interlayer space. The antibacterial properties were evaluated against E. coli and S. typhi strains through dilution broth method. MgFeAl-Cl matrix resulted to be completely inactive against two bac-teria, while MgFeAl-PIP composite killed all colonies of E. coli after 90 min of exposure and showed a good activity to kill S. typhi bacteria at times as short as 120 min.

Direct contact, dissolution and generation of reactive oxygen species: How to optimize the antibacterial effects of layered double hydroxides

“…Nearly all of the studies dealing with the antibacterial activity of antibacterial organic molecules-281 loaded LDHs are mainly concerned with the controlled release of the active biomolecule out of the 282 LDH matrix [31,46,87,93,96,[98][99][100], which is the main contributor to the followed antibacterial 283 mechanism. .…”

Heterogeneous Fenton Degradation of Organic Pollutants in Water Enhanced by Combining Iron‐type Layered Double Hydroxide and Sulfate

“…The diffraction patterns derived from the layer structure of LDH ascribed to the (003) and (006) planes (JCPDS No. 22‐700 [4d] as a typical LDH structure) [3,4a–d] were largely confirmed in both samples, and iron oxide hydroxide (α‐FeOOH, JCPDS No. 29‐0713 [4e] ) derived from trivalent iron species was also formed as a by‐product (Figure 2(A) and Table S1).…”

“…LDH possesses layer structure of complex hydroxides derived from divalent and trivalent metal ions, and various anions can be immobilized between the layers. The unique properties have been widely utilized to develop applications in various fields including catalysis [1h–i,3,4a–d] . Almost all previous investigations using Fe 2+ Al 3+ ‐LDH have focused solely on its application to adsorption treatment of toxic metallic or halide ions, [3] and little attention has so far been paid to using this material as a heterogeneous Fenton catalyst for the treatment of organic pollutants [1h–i] .…”

“…In particular, Fe 2+ Al 3+ ‐LDH could be expected not only to be used as a heterogeneous Fenton catalyst because of the Fe 2+ contained in its layers, but also to directly immobilize various anions providing described above unique property by reaction with H 2 O 2 within the interlayers of the LDH structure (Figure 1(B)). In addition, Al 3+ has been widely utilized as one of the basic species of trivalent metal ion to compose stable LDH structure [4a–d] . However, there have so far been no studies reporting the effects of anion species in Fe 2+ Al 3+ ‐LDH on the mineralization to CO 2 of organic pollutants.…”

Direct contact, dissolution and generation of reactive oxygen species: How to optimize the antibacterial effects of layered double hydroxides

“…Nearly all of the studies dealing with the antibacterial activity of antibacterial organic molecules-327 loaded LDHs are mainly concerned with the controlled release of the active biomolecule out of the 328 LDH matrix [29,51,89,94,100,[104][105][106], which is the main contributor to the followed 329 antibacterial mechanism. One example of controlled release behavior of antibacterial molecule-330 loaded LDHs is the controlled delivery of Kojic acid (KA) out of ZnTi LDH illustrated in Fig.…”