Antibacterial Activity of Copper Particles Embedded in Knitted Fabrics

Ivanauskas, Remigijus; Bronusiene, A.; Ivanauskas, Algimantas; Šarkinas, Antanas; Ancutienė, Ingrida

doi:10.3390/ma15207147

Cited by 4 publications

(3 citation statements)

References 30 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The antimicrobial properties of L-PEI-based hydrogels and cryogels were determined by the macro-dilution method and a zone of inhibition experiment against E. coli (ATCC 8739) and B. subtilis (ATCC 6633) as Gram-negative and Gram-positive bacteria, respectively, by following the previous procedures [ 31 , 32 ]. Reisner and Woods discovered that only seven microorganisms cause 85–90% of all clinically reported illnesses, with E. coli being responsible for almost half of all infections [ 33 ].…”

Section: Methodsmentioning

confidence: 99%

Physically and Chemically Crosslinked, Tannic Acid Embedded Linear PEI-Based Hydrogels and Cryogels with Natural Antibacterial and Antioxidant Properties

2023

View full text Add to dashboard Cite

Linear polyethyleneimine (L-PEI) was obtained from the acidic hydrolysis of poly(2-ethyl-2-oxazoline) and employed in the synthesis of physically crosslinked L-PEI hydrogel, PC-L-PEIH, chemically crosslinked L-PEI hydrogel, CC-L-PEIH, and cryogels, CC-L-PEIC. The preparation of L-PEI-based hydrogel networks was carried out in two ways: 1) by cooling the L-PEI solution from 90 °C to room temperature, and 2) by crosslinking L-PEI chains with a crosslinker, glycerol diglycidyl ether = 20 °C for CC-L-PEIC. Furthermore, a polyphenolic compound, tannic acid (TA), with superior antibacterial, antioxidant, and anti-inflammatory properties as an active biomedical functional agent, was encapsulated during the synthesis process within L-PEI-based hydrogels and cryogels, at 10% and 25% (w/w) based on the L-PEI amount. A linear and higher TA release was observed from physically crosslinked PEI-based hydrogels containing 10% and 25% TA-containing PC-L-PEI/TAH within 6 h, with 9.5 ± 05 mg/g and 60.2 ± 3.8 mg/g cumulative released amounts, respectively. A higher antioxidant activity was observed for 25% TA containing PC-L-PEI/TAH with 53.6 ± 5.3 µg/mL total phenol content and 0.48 ± 0.01 µmole Trolox equivalent/g. The minimum bactericidal concentration (MBC) of PC-L-PEIH and CC-L-PEIC networks against both E. coli (ATCC 8739) and Gram-positive B. subtilis (ATCC 6633) bacteria was determined at 5 mg/mL, whereas the MBC value of 10 mg/mL for CC-L-PEIH networks against the same bacteria was achieved.

show abstract

Section: Methodsmentioning

confidence: 99%

Physically and Chemically Crosslinked, Tannic Acid Embedded Linear PEI-Based Hydrogels and Cryogels with Natural Antibacterial and Antioxidant Properties

2023

View full text Add to dashboard Cite

show abstract

“…Metal ions have emerged as potential candidates due to their distinct antibacterial properties compared to conventional antibiotics [2]. Silver and copper in particular have gained significant attention as antibacterial biomaterials due to several advantages [3,4]. The correlation between the antibacterial property and cytotoxicity of metal ions exhibits substantial variability, and the precise mechanisms underlying the antimicrobial property of metal ions remain inadequately elucidated [5][6][7].…”

Section: Introductionmentioning

confidence: 99%

Metal copper and silver revealed potent antimicrobial activity for treating Caenorhabditis elegans infected with carbapenemase-producing Klebsiella pneumonia

Cao

2024

Am J Transl Res

View full text Add to dashboard Cite

Objectives: The increasing issue of bacterial resistance, coupled with inadequate progress in developing new antibiotics, necessitates exploring alternative treatments. Antibacterial biomaterials, such as silver and copper, possess advantageous properties such as heat resistance, durability, continuity, and safety. Particularly, they can effectively eliminate pathogenic bacteria while preserving cellular integrity, emphasizing the necessity of identifying optimal metal ion concentrations for practical application. Caenorhabditis elegans (C. elegans) can serve as a noteworthy model in this context. This study employed a C. elegans infection model to assess the efficacy of antibacterial metal ions. Methods: Hematoxylin-eosin (HE) staining and inductively coupled plasma mass spectrometry (ICP-MS) assay were utilized to determine the toxic levels of metal ions in mice. Additionally, RNA sequencing (RNA-seq) and assessment of reactive oxygen species (ROS) production in the C. elegans model were conducted to elucidate the mechanisms underlying metal ion toxicity. Results: Silver ion concentrations ranging from 10 -6 to 10 -7 M and copper ion concentrations ranging from 10 -4 to 10 -5 M exhibited antimicrobial properties without eliciting cytotoxic effects. Analysis of the transcriptome data derived from mRNA isolated from C. elegans indicated that CRKP infection activated the FoxO signaling pathway, potentially leading to ROS accumulation and C. elegans demise. Conclusions: In conclusion, C. elegans serves as a comprehensive infection model for assessing antibacterial metal ions.

show abstract

“…The antibacterial finish applied to softened knitted fabrics did not change the physical properties of the samples. Ivanauskas and co-workers [14] obtained antibacterial knitted fabrics modified with copper particles synthesized using copper sulfate as a precursor and ascorbic acid as a natural reducing agent. The authors examined samples of woolen and cotton knitted fabrics with copper particles that showed antibacterial activity against E. coli and S. aureus.…”

Section: Introductionmentioning

confidence: 99%

Knitted Structures Made of Antibacterial Fibers Intended for Protective Gloves

Smiechowicz,

Niekraszewicz,

Klonowska

et al. 2023

Materials

View full text Add to dashboard Cite

At a time of growing epidemic hazards caused by a very rapid evolution of dangerous pathogens, there is a pressing demand for bioactive textiles. Therefore, the development of high-quality knitted structures that could be used as bioactive protective materials has become a priority. This publication describes the fabrication of functional knitted structures from previously prepared antibacterial cellulose fibers containing nanosilica with immobilized silver nanoparticles. The structural and physical parameters of knitted fabrics made from them were studied with a view to their potential application in bioactive protective gloves. Tests of the basic structural and physical parameters of the knitted fabrics did not show that the nanomodifier applied in fibers significantly impacts the physical properties of the resulting fabrics. Moreover, water vapor permeability, cut resistance, and pH test results relevant to the functional and protective properties of interest and to user comfort showed that the obtained fabrics can be used in the production of bioactive protective gloves.

show abstract

Antibacterial Activity of Copper Particles Embedded in Knitted Fabrics

Cited by 4 publications

References 30 publications

Physically and Chemically Crosslinked, Tannic Acid Embedded Linear PEI-Based Hydrogels and Cryogels with Natural Antibacterial and Antioxidant Properties

Physically and Chemically Crosslinked, Tannic Acid Embedded Linear PEI-Based Hydrogels and Cryogels with Natural Antibacterial and Antioxidant Properties

Metal copper and silver revealed potent antimicrobial activity for treating Caenorhabditis elegans infected with carbapenemase-producing Klebsiella pneumonia

Knitted Structures Made of Antibacterial Fibers Intended for Protective Gloves

Contact Info

Product

Resources

About