Saxifraga ligulata belongs to family saxifragaceae, is an accepted source of ayurvedic medicine Pashanabheda. This plant has been already recognized for its role in dissolving kidney stone. This review supports all updated information on its chemical constituents, pharmacological activities, traditional uses and scientific approach. The chemical entities of this plant have been used as an Antibacterial, Antiviral, Antipyretic, Antidiabetic, Anti inflammatory, Diuretic, Antiurolithiatic, Antioxidant, Antitussive and Hepatoprotective. This review is studied for the further development of various formulations for their traditional use and Pharmacological activities.