Antibacterial Activity and Phytochemical Analysis of &amp;lt;i&amp;gt;Mentha piperita&amp;lt;/i&amp;gt; L. (Peppermint)—An Important Multipurpose Medicinal Plant

Sujana, P; Sridhar, T.M.; Josthna, P.; Naidu, C.V.

doi:10.4236/ajps.2013.41012

Cited by 57 publications

(41 citation statements)

References 12 publications

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“…Similar studies in Mentha piperita 25 showed the presence of alkaloids, flavonoids, steroids, tannins, and phenols.…”

Section: Figure 2: Tlc Profile Of the Petroleum Ether Fraction Of Leamentioning

confidence: 51%

Untitled

2014

IJPSR

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Purpose: The focus of the present paper was a preliminary phytochemical and TLC analysis of the various extracts (root, stem and leaf) of the mangrove plant Excoecaria agallocha L. Methods: Phytochemical analysis was carried out using the standard phytochemical assays. TLC analysis of the petroleum ether and chloroform fraction of the leaves was carried out using the solvent system Toluene: Ethyl acetate (in 9:1 ratio) and Toluene: Ethyl acetate: Formic acid (in 5:5:0.2 ratio) for PE and chloroform fractions respectively. Result and conclusion: The results of the preliminary phytochemical screening revealed the presence of various chemical compounds like alkaloids, glycosides, flavonoids, carbohydrates, anthraquinone, tannins, phenols, terpenoids, fixed oil and fats. Organoleptic study revealed the specific nature of the plant parts used in the study. The behavior of the powdered plant parts in presence of various chemicals was studied. TLC analysis of the petroleum ether and chloroform fraction of the leaves of Excoecaria agallocha L. revealed bands indicating the presence of various compounds that could act as potential antimicrobial agents.

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“…Similar studies in Mentha piperita 25 showed the presence of alkaloids, flavonoids, steroids, tannins, and phenols.…”

Section: Figure 2: Tlc Profile Of the Petroleum Ether Fraction Of Leamentioning

confidence: 51%

Untitled

2014

IJPSR

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“…The bactericidal properties of menthol and its effective inhibitory potential against gram positive bacteria has also previously been reported (8). In a previous study, Sujana et al (2013) evaluated the antibacterial potential of six extracts from the leaves, stems, and roots of M. piperita against pathogenic bacteria such as Bacillus subtilis, Streptococcus pneumonia, Staphylococcus aureus, Escherichia coli, Proteus vulgaris, and Klebsiella pneumonia by the agar well diffusion method (20). They reported that the antimicrobial activity of the leaf extract was more powerful against Bacillus subtilis, Staphylococcus aureus, and Proteus vulgaris than against Escherichia coli, Streptococcus pneumonia, and Klebsiella pneumonia.…”

Section: Discussionmentioning

confidence: 99%

Bioactive Potential of Peppermint Extract Against Some Human Bacterial and Fungal Pathogens

Farzaei¹,

Azizi²,

Arji³

et al. 2015

Avicenna J Clin Microbiol Infect

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Background: Bacterial and fungal infections are an emerging public health concern, especially in the context of nosocomial infections. This study discusses the use of peppermint (Mentha piperita L.) methanolic extract against bacterial strains such as Escherichia coli, Pseudomonas aeruginosa, Bacillus subtilis, and Staphylococcus aureus and fungal species such as Trichophyton mentagrophytes, Trichophyton verrucosum, and Candida albicans. Objectives: This research aimed to investigate the inhibitory potential of M. piperita methanolic extract against some bacteria and fungi isolated from humans. Materials and Methods: The methanolic extract was prepared by standard procedure, and total phenol, total flavonoid, and total anthocyanin content were determined using a spectrophotometer. Antimicrobial activity against the aforementioned bacteria and fungi strains was evaluated using the disc diffusion method. Results: The contents of total phenol, flavonoid, and anthocyanin as well as antimicrobial activities and antifungal properties were enhanced by the increase of extract concentration. The results showed that the antimicrobial activity of leaf extract was more powerful against Bacillus subtilis (1.39 mm) than Staphylococcus aureus (1.29 mm), Escherichia coli (1.20 mm), and Pseudomonas aeruginosa (1.10 mm) based on the growth inhabitation zone. The most powerful antifungal activity of peppermint extract was observed against Trichophyton verrucosum and Trichophyton mentagrophytes (1.49 and 1.48 mm, respectively). Conclusions: Due to phenolic content, methanolic extract of M. piperita has moderate antibacterial and antifungal properties against the aforementioned gram positive and gram negative bacteria and fungi strains.

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“…Over the time S. aureus, K. pneumoniae, and S. pneumoniae is gaining resistance to the antibiotics. S. pneumoniae is one of the causative organisms of hospital-acquired pneumonia [26]. S. pneumoniae is mainly affecting the nasal pharynx, trachea, and lungs [27] occur in the lungs, where they cause necrosis, inflammation, and hemorrhage within the lung tissue.…”

Section: Resultsmentioning

confidence: 99%

Phytochemical Screening and Evaluation of in-Vitro Antimicrobial Activity of Drosera Spatulata Var Bakoensis- an Indigenous Carnivorous Plant Against Respiratory Tract Infectious Microbes.

Tulasi¹

2016

Asian J Pharm Clin Res

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Objective: In the present study, phytochemical constituents of Drosera spatulata var. bakoensis have been evaluated, and antimicrobial activity was screened against respiratory tract infectious microbes. Methods:The phytochemicals present in D. bakoensis by qualitative phytochemical assays and aqueous, ethanol, methanol extracts of thick roots, open flower, and hair of D. bakoensis against this pathogenic bacteria and fungi showed a high zone of inhibition which estimated by disc diffusion method as well as minimum inhibitory concentration (MIC) manifestation by the broth microdilution assay followed minimum bactericidal concentration (MBC) and biofilm inhibitory concentrations (BICs) were determined against Staphylococcus aureus, Klebsiella pneumoniae, and Staphylococcus pneumoniae the causative organisms of pulmonary infections, mainly effects the nasal pharynx, trachea, and lungs as well as Aspergillus niger. Results:The values of MIC, MBC, and BIC obtained were between 0.3-0.9, 0.36-2.25, and 0.12-0.37 mg/mL, respectively. In the antibacterial and antifungal activity, results revealed that ethanol and methanol extracts significantly showed activity against the tested respiratory disease causing bacteria and antifungal properties to the zone of inhibition showed more than aqueous extracts at very low concentrations. Conclusion:The plant extracts of D. bakoensis have high potential even at low concentrations values against bacteria and fungi cultures, and these results validated by the presence of high amounts of alkaloids, quinones, anthraquinones, and flavonoids in the plant extracts which have tremendous impact against respiratory infectious microbes.

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Antibacterial Activity and Phytochemical Analysis of <i>Mentha piperita</i> L. (Peppermint)—An Important Multipurpose Medicinal Plant

Cited by 57 publications

References 12 publications

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Bioactive Potential of Peppermint Extract Against Some Human Bacterial and Fungal Pathogens

Phytochemical Screening and Evaluation of in-Vitro Antimicrobial Activity of Drosera Spatulata Var Bakoensis- an Indigenous Carnivorous Plant Against Respiratory Tract Infectious Microbes.

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