Antibacterial activity and physicochemical characterization of calcium-aluminium-ciprofloxacin-layered double hydroxide

Jadam, Monica Limau; Mohamad, Sharifah Aminah Syed; Zaki, Hamizah Mohd; Jubri, Zaemah; Sarijo, Siti Halimah

doi:10.1016/j.jddst.2020.102314

Cited by 14 publications

(17 citation statements)

References 30 publications

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“…PXRD Analysis and Spatial Orientation of 2,4-DP Fig. 3 portrays the PXRD patterns of both the Ca-Al LDH host and its nanocomposite, CAL-2,4DP, at various concentrations in the range of 0.025-0.1 M. The pattern of Ca-Al LDH showed high crystallinity and harmonious peaks, which is consistent with the typical LDH host [7][8][9]15]. It also has a well-defined peak at 10.34° corresponding Here, the difference in the basal spacing is pronounced compared to the LDH host due to the anion size of 2,4-DP, which is larger than the nitrate ions, and the spatial orientation between the interlayers [15].…”

Section: ■ Results and Discussionmentioning

confidence: 61%

“…6. Depending on the IUPAC (International Union of Pure and Applied Chemistry) categorization, the isotherms resemble Type IV sorption, indicating mesopore-type material with an H3 hysteresis loop [7]. The hysteresis loop for the CAL-2,4DP observed has a broader adsorption branch than the Ca-Al LDH due to the interleaving process of the 2,4-DP anion replacing the nitrate ion.…”

Section: Surface Propertiesmentioning

confidence: 99%

“…x (OH 2 )] x+ (A n− ) x/n •yH 2 O], in which M 2+ and M 3+ denote the divalent and trivalent cations such as calcium (Ca 2+ ) and aluminum (Al 3+ ) accordingly, meanwhile A n− is the interlayer anion [3]. The brucite-like sheets are positively charged, in which some part of the divalent cations can be substituted with the trivalent cations [5][6][7][8]. The negative charges reside in the hydrated interlayer to compensate for the positively charged sheets and keep the charges balanced while providing its typical stacked layered structures.…”

Section: ■ Introductionmentioning

confidence: 99%

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Synthesis and Characterization of 2,4-Dichlorophenoxypropanoic Acid (2,4-DP) Herbicide Interleaved into Calcium-Aluminium Layered Double Hydroxide and the Study of Controlled Release Formulation

Bohari

Noor²,

Ghazali³

et al. 2022

Indones. J. Chem.

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The commonly used herbicide in agriculture, namely 2,4-dichlorophenoxypropanoic acid (2,4-DP), is an anionic herbicide used to interleave into the interlayer of calcium-aluminum layered double hydroxide (Ca-Al LDH) employing co-precipitation method to form a new nanohybrid labeled as CAL-2,4DP. The LDH compound serves as a host in supporting the herbicide’s controlled release formulation. The effective interleave was investigated by employing a powder X-Ray Diffraction (XRD) pattern at 0.025 M nanocomposite, which revealed that the basal spacing has increased from 8.0 Å to 23.8 Å. The ATR-FTIR spectra further supported the interleaving, where the nitrate peak (NO−) diminished, and the carboxylate ion (COO−) band appeared at 1653 cm−1. The percentage loading of CAL-2,4DP was 71.26%, calculated from the carbon content in the sample. The BET analysis shows that CAL-2,4DP was a mesoporous material relying on nitrogen-desorption isotherms. The release of 2,4-DP ions into the aqueous solutions followed the order of PO43− > CO32− > Cl− with a percentage of 83, 65, and 30%, respectively. This work indicates the successful interleaving process of the 2,4-DP anion and the potential of CAL-2,4DP as an eco-friendly agrochemical that can be beneficial for farmers in minimizing herbicide usage to the environment.

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Section: ■ Results and Discussionmentioning

confidence: 61%

Section: Surface Propertiesmentioning

confidence: 99%

Section: ■ Introductionmentioning

confidence: 99%

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Synthesis and Characterization of 2,4-Dichlorophenoxypropanoic Acid (2,4-DP) Herbicide Interleaved into Calcium-Aluminium Layered Double Hydroxide and the Study of Controlled Release Formulation

Bohari

Noor²,

Ghazali³

et al. 2022

Indones. J. Chem.

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“…The encapsulation efficiency of Cip was analyzed according to the procedure reported by Jadam et al The amount of free ciprofloxacin in the supernatant was determined by UV–vis spectrophotometer at 270 nm. The loading rate was calculated according to the following equation. EE % = false( T − F false) T 100 where F is the amount of free drug in the supernatant, and T is the total amount of added drug in the mixed solution.…”

Section: Methodsmentioning

confidence: 99%

“…Evaluation of Ciprofloxacin Incorporation Rate. The encapsulation efficiency of Cip was analyzed according to the procedure reported by Jadam et al 21 The amount of free ciprofloxacin in the supernatant was determined by UV−vis spectrophotometer at 270 nm. The loading rate was calculated according to the following equation.…”

Section: Preparation Of Jfmsmentioning

confidence: 99%

Intelligent Jellyfish-type Janus Nanoreactor Targeting Synergistic Treatment of Bacterial Infections

Huang,

Liu,

Guo

et al. 2023

ACS Appl. Bio Mater.

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Infections caused by multidrug-resistant bacteria continue to pose a serious threat to human health, and therefore it is important to explore the availability of antimicrobial drugs and modalities. Herein, jellyfish-type irregular mesoporous iron oxide nanoreactors containing ciprofloxacin, Janus Fe 3 O 4 @ mSiO 2 @Cip nanoparticles (JFmS@Cip NPs), were developed for pH-responsive synergistic antimicrobial therapy in a microacidic environment. Compared with the use of symmetric nanocarriers, the asymmetric decoration on both sides of the particles allows different components to act on bacteria, Fe 3 O 4 NPs have good magnetic and peroxidase-like catalytic activity, and the antibiotic ciprofloxacin can kill bacteria efficiently. Notably, due to the synergistic effect between different components of Janus particles, in vitro antibacterial experiments showed that JFmS@ Cip NPs can kill bacteria efficiently at low concentrations, reaching an antibacterial rate of 99.6%. JFmS@Cip NPs combine multiple antibacterial properties that can be used to improve the therapeutic efficacy of current nanomedicines against drug-resistant bacteria.

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Microstructural tuning and band gap engineering of calcium hydroxides: a novel approach by pH variation

et al. 2022

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Here we report a simple, inexpensive, energy benign, yet novel pH‐driven chemical precipitation technique to achieve microstructural and band gap engineering of calcium hydroxide nanoparticles (CHNPs). The chemical precipitation route involved the use of 0.4–1.6 M Ca(NO3)2.4H2O solutions as the precursor and 1 M NaOH solution as the precipitator. The simple variation in precursor molarity induces a pH change from about 12.4 to 11.3 in the reactant solution. The CHNPs characterized by X‐ray diffraction (XRD), field emission scanning electron microscopy (FESEM), Fourier transform infrared spectroscopy (FTIR), dynamic light scattering (DLS), and ultraviolet–visible (UV–Vis) spectroscopy techniques confirm a jump of nanocrystallite size from ~50–70 nm with a concomitant reduction of direct optical band gap energy from ~5.38–5.26 eV. The possible mechanisms that could be operative behind obtaining microstructurally tuned (MT)‐CHNPS and band gap engineering (BGE) are discussed from both theoretical and physical process perspectives. Furthermore, the implications of these novel results for possible futuristic applications are briefly hinted upon.

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Antibacterial activity and physicochemical characterization of calcium-aluminium-ciprofloxacin-layered double hydroxide

Cited by 14 publications

References 30 publications

Synthesis and Characterization of 2,4-Dichlorophenoxypropanoic Acid (2,4-DP) Herbicide Interleaved into Calcium-Aluminium Layered Double Hydroxide and the Study of Controlled Release Formulation

Synthesis and Characterization of 2,4-Dichlorophenoxypropanoic Acid (2,4-DP) Herbicide Interleaved into Calcium-Aluminium Layered Double Hydroxide and the Study of Controlled Release Formulation

Intelligent Jellyfish-type Janus Nanoreactor Targeting Synergistic Treatment of Bacterial Infections

Microstructural tuning and band gap engineering of calcium hydroxides: a novel approach by pH variation

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