Antibacterial Activities of Oenothera laciniata Extracts

김지영,; 이정아,; 박수영,

doi:10.3746/jkfn.2007.36.3.255

Cited by 14 publications

(6 citation statements)

References 6 publications

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“…O. laciniata ( O. laciniata Hill) is a species endemic to Jeju Island, Korea with a seaside habitat. O. laciniata extract has been reported to contain bioactive substances with antioxidative activity, cytotoxic activity against a leukemia cell line, and antibacterial activity ( 12 , 13 ).…”

Section: Introductionmentioning

confidence: 99%

Anti-Melanogenic Effect ofOenothera laciniataMethanol Extract in Melan-a Cells

2017

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We evaluated the antioxidant activity and anti-melanogenic effects of Oenothera laciniata methanol extract (OLME) in vitro by using melan-a cells. The total polyphenol and flavonoid content of OLME was 66.3 and 19.0 mg/g, respectively. The electron-donating ability, 2,2′-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid) (ABTS) radical-scavenging activity, and superoxide dismutase (SOD)-like activity of OLME (500 μg/mL) were 94.5%, 95.6%, and 63.6%, respectively. OLME and arbutin treatment at 50 μg/mL significantly decreased melanin content by 35.5% and 14.2%, respectively, compared to control (p < 0.05). OLME and arbutin treatment at 50 μg/mL significantly inhibited intra-cellular tyrosinase activity by 22.6% and 12.6%, respectively, compared to control (p < 0.05). OLME (50 μg/mL) significantly decreased tyrosinase, tyrosinase-related protein-1 (TRP-1), TRP-2, and microphthalmia-associated transcription factor-M (MITF-M) mRNA expression by 57.1%, 67.3%, 99.0%, and 77.0%, respectively, compared to control (p < 0.05). Arbutin (50 μg/mL) significantly decreased tyrosinase, TRP-1, and TRP-2 mRNA expression by 24.2%, 42.9%, and 48.5%, respectively, compared to control (p < 0.05). However, arbutin (50 μg/mL) did not affect MITF-M mRNA expression. Taken together, OLME showed a good antioxidant activity and anti-melanogenic effect in melan-a cells that was superior to that of arbutin, a well-known skin-whitening agent. The potential mechanism underlying the anti-melanogenic effect of OLME was inhibition of tyrosinase activity and down-regulation of tyrosinase, TRP-1, TRP-2, and MITF-M mRNA expression.

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Section: Introductionmentioning

confidence: 99%

Anti-Melanogenic Effect ofOenothera laciniataMethanol Extract in Melan-a Cells

2017

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“…총 페놀 화합물 함량 페놀화합물은 식물계에 널리 분포되어 있는 2차 대사산물로 서 phenolic acid류, phenylprophanoid류, flavonoid류 등이 대 부분이다 [25]. 이는 phenolic hydroxyl기를 가지고 있어 단백 질 또는 효소, 기타 거대분자들과 결합하는 성질이 있으며 또 한 항균, 항산화 및 항암 등의 다양한 생리활성기능을 가진 것으로 알려져 있다 [26,27]. 페놀 화합물의 항산화 작용은 수 산기를 통한 수소 공여로 라디칼들과 쉽게 공명으로 안정화 될 수 있는 구조를 가지고 있어 항산화 활성을 가지는 것으로 보고되고 있다 [28].…”

Section: Resultsunclassified

Antioxidant Effect of Sargassum coreanum Root and Stem Extracts

박지혜¹,

배난영²,

박선희³

et al. 2015

KSBB Journal

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The present study was to investigate the antioxidant activity in ethanol and water extracts of root and stem of Sargassum coreanum. Antioxidant activities were evaluated by total polyphenol contents, DPPH radical scavenging activity, chelating effect, reducing power, and rancimat method. Total polyphenol contents of ethanol and water extracts were 32.79 mg/g and 15.55 mg/g, respectively. Ethanol extract showed higher DPPH radical scavenging activity than water extract and similar activity to BHT. Reducing power of extracts was increased in a concentration-dependent manner and ethanol extract had more reducing power than water extract. Ethanol and water extracts have little chelating effect at all concentrations. Antioxidant index (AI) of ethanol extract measured by Rancimat was higher than that of water extract, but their AI was lower than that of BHT. These results indicate that ethanol extract of S. coreanum root and stem has more potent antioxidant activity than water extract through DPPH radical scavenging and reducing power, and could potentially be used as a good source of natural antioxidants.

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“…화, 항염증, 항암 등이 보고된 바 있어 산업적으로 이용 가치가 높다고 평가되고 있으며 특히 달맞이꽃의 씨의 생리활성 연구는 매우 활발한 편이다 (Yoon et al, 2009;Almora-Pinedo et al, 2017;Timoszuk et al, 2018;Pajak et al, 2019). Oenothera 속 달맞이꽃의 항균 작용과 관련하여 애 기달맞이꽃(Oenothera laciniata) 전초 80% 에탄올 추출물 과 분획물이 항균효과를 보였으며 (Kim et al, 2007) 달맞이 꽃(Oenothera biennis) 70% 에탄올 추출물의 경우 S. aureus, E. coli, S. Typhi에 대해서는 성장억제 효과를 보이지 않았 으나 Bacillus cereus에 대해서는 성장억제를 보였다 (Kim and Lee, 2016). 긴잎달맞이꽃(Oenothera odorata) 뿌리 75% 메탄올 추출물과 분획물 대상으로 항균효과 실험했을 때 는 클로로포름 분획물이 Streptococcus 속에 대해 상대적으 로 높은 항균력 보였다 (Shin et al, 1994 (Fig.…”

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“…지유는 2.5 mg/mL (Park et al, 2001), 발효 강황은 0.5~1 mg/mL (Ra and Kim, 2016) 이어서 O. lamarckiana 지상부의 메탄올 추출물의 S. aureus 와 MRSA에 대한 항균력은 비교적 뛰어난 것으로 보인 다. Kim et al (2007)…”

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“…시료들 간의 통 계분석은 GraphPad Prism 6을 이용하여 일원분산분석과 turkey's multiple comparisons로 이뤄졌다(P < 0.05). Paper disc assay에서 O. biennis 전초 건조물의 70% 에탄 올 추출물이 B. cereus에 대해서는 항균효과를 보였으나 S. aureus, E. coli 및 S. Typhimurium에 대해서는 항균효과를 이지 않은 것으로 보고된 바 있으며(Kim and Lee, 2016) O. laciniata 전초의 80% 에탄올 추출물 및 분획물의 경우 에틸아세테이트 분획물이 B. cereus, L. monocytogenes, S. aureus, E. coli, S. enteritidis, S. Typhimurium에 대해 가장 강력한 항균력을 보였다(Kim et al, 2007). 본 연구에서 O. lamarckiana 지상부의 메탄올 추출물은 20 μg/disc에서 실험 대상이 된 박테리아에 대해 clear zone을 보이지 않 았지만 200 μg/disc에서 S. aureus, MRSA, B. cereus와 S.…”

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