2016
DOI: 10.1080/21501203.2016.1263688
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Antiangiogenic, wound healing and antioxidant activity ofCladosporium cladosporioides(Endophytic Fungus) isolated from seaweed (Sargassum wightii)

Abstract: Endophytic fungi from marine seaweeds are the less studied group of organisms with vast medical applications. The aim of the present study was to evaluate antioxidant, antiangiogenic as well as wound healing potential of the endophytic fungus isolated from the seaweed Sargassum wightii. The morphological characters and the rDNA internal transcribed spacer sequence analysis (BLAST search in Gen Bank database) was used for the identification of endophytic fungus. The antioxidant potential of the ethyl acetate ex… Show more

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Cited by 20 publications
(9 citation statements)
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“…In this study, an endophytic fungus P. oxalicum from C. limon was found to possess good antioxidant activity. Many endophytic fungi from therapeutically important plants have been found to exhibit strong antioxidant potential (Xiaoli et al ; Huang et al ; Yadav et al ; Hulikere et al ). Antioxidant activity of an endophytic P. oxalicum isolated from Cupressus torulosa has also been reported by Bisht et al ().…”
Section: Discussionmentioning
confidence: 99%
“…In this study, an endophytic fungus P. oxalicum from C. limon was found to possess good antioxidant activity. Many endophytic fungi from therapeutically important plants have been found to exhibit strong antioxidant potential (Xiaoli et al ; Huang et al ; Yadav et al ; Hulikere et al ). Antioxidant activity of an endophytic P. oxalicum isolated from Cupressus torulosa has also been reported by Bisht et al ().…”
Section: Discussionmentioning
confidence: 99%
“…The qualitative chemical screening of crude extract showed the presence of phenolics, alkaloids, flavanoids, steroids and terpenoids as major secondary metabolite constituent. Presence of such a variety of compounds in the fungus makes it a potential candidate for exploration of bioactive compounds (Hulikere et al, 2016 ). Further, GCMS analysis revealed presence in TPEE of many cytotoxic and antioxidative compounds including 3-nitropropanoic acid, 4H-pyran-4-one, 5-hydroxy-2-(hydroxymethyl), hexadecanoic acid, and octadecanoic acid.…”
Section: Discussionmentioning
confidence: 99%
“…The wound healing efficiency enhanced 295% in SGE-treated CCD-966SK cells when compared to the control. The components of Sargassum species has been proven to be effective in anti-angiogenesis by inhibiting cancer cell migration and proliferation in the wound healing assay [17,32]. However, our data showed that SGE could be potentially used in repairing the wound of dermal fibroblasts.…”
Section: Sge Stimulated Ccd-966sk Fibroblast Migration In the Wound Hmentioning
confidence: 72%