Anti-Ulcer Activity of Adhatoda vasica Nees

Shrivastava, Neeta; Srivastava, Anshu; Banerjee, Aryamitra; Nivsarkar, Manish

doi:10.1300/j157v06n02_04

Cited by 25 publications

(22 citation statements)

References 4 publications

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“…Accumulation of activated neutrophils in the gastric mucosa may be a source of this free radical generation. [17][18][19] Shrivastava et al The drug has shown modulatory effect on enzymes involved in lipid peroxidation 5 and prevention of carbon tetrachloride-induced hepatotoxicity in rats.…”

Section: Discussionmentioning

confidence: 99%

Anti-Ulcer Activity ofAdhatoda vasicaNees

Shrivastava

Srivastava

Banerjee

et al. 2006

Journal of Herbal Pharmacotherapy

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Adhatoda vasica Nees (Acantheceae), commonly known as Vasaka, is a well-known plant in indigenous systems of medicine and is used for its beneficial effects, particularly in bronchitis. The present investigation was carried out to study the anti-ulcer activity of Adhatoda vasica leaves using two ulcer models (1) Ethanol-induced, and (2) Pylorus ligation plus aspirin-induced models. Adhatoda vasica leaf powder showeda considerable degree of anti-ulcer activity in experimental rats when compared with a control. The highest degree of activity (80%) was observed in the ethanol-induced ulceration model. Results of the study suggest that in addition to its classically established pharmacological activities, the plant also has immense potential as an anti-ulcer agent of great therapeutic relevance.

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Section: Discussionmentioning

confidence: 99%

Anti-Ulcer Activity ofAdhatoda vasicaNees

Shrivastava

Srivastava

Banerjee

et al. 2006

Journal of Herbal Pharmacotherapy

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“…The Leaves of Adhatoda vasica possessed anti-ulcer activity. Adhatoda leaf powder showed a considerable degree of anti-ulcer activity in rats with the highest degree of activity (80%) observed in the ethanol-induced ulceration model in comparison to pylorus, and aspirin (Shrivastava et al, 2006).…”

Section: Anti-ulcer Activitymentioning

confidence: 99%

Therapeutic use of Adhatoda vasica

Hossain

Hoq

2016

Asian J. Med. Biol. Res

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Adhatoda vasica Nees belonging to family Acanthaceae, commonly known as Adosa, is found many regions of India and throughout the world, with a multitude of uses in traditional Unani and Ayurvedic systems of medicine. It is also called Vasaka. It is a well-known herb in indigenous systems of medicine for its beneficial effects, particularly in bronchitis. Vasaka leaves, bark, the root bark, the fruit and flowers are useful in the removal of intestinal parasites. Vasaka herb is used for treating cold, cough, chronic bronchitis and asthma. In acute stages of bronchitis, vasaka gives unfailing relief, especially where the sputum is thick and sticky. It liquefies the sputum so that it is brought up more easily. For relief in asthma, the dried leaves should be smoked. The juice from its leaves should be given in doses of 2 to 4 grams in treating diarrhea and dysentery. A poultice of its leaves can be applied with beneficial results over fresh wounds, rheumatic joints and inflammatory swellings. A warm decoction of its leaves is useful in treating scabies and other skin diseases. In olden times its leaves were made into a decoction with pepper and dried ginger. But the modern medicine searched its active ingredients and found out that vasicine, oxyvascicine and vasicinone are the alkaloids present in vasaka and in which vasicine is the active ingradient for expelling sputum from the body.Asian J. Med. Biol. Res. June 2016, 2(2): 156-163

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“…The highest degree of activity (80%) was observed in the ethanol-induced ulceration model. [65] In a clinical study, to assess effect of AV on non-ulcer dyspepsia (Amlapitta) a 60 ml syrup of dry leaves of AV was given to patient in 4 divided doses for 6 weeks. Significant effect was observed in the symptoms of pyrosis and burning sensation in abdomen.…”

Section: Effect On Gastrointestinal Tractmentioning

confidence: 99%

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Kapgate¹

2017

IJGP

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Natural products are the most important source for discovery of new and effective drug molecules. The emergence of drug-resistant pathogens and the increase in diseases affecting the immune system have greatly intensified the need to investigate new bioactive metabolites for potential pharmaceutical and industrial applications. Ayurvedic classics have a unique wealth of medicinal plants and vast traditional knowledge of herbal medicine for the cure of various diseases. Adhatoda vasica (Nees) (AV) of family Acanthaceae, is a shrub growing throughout the Indian peninsula. The frequent use of AV has resulted in its inclusion in the WHO manual -The Use of Traditional Medicine in Primary Health Care. Thus, extensive research work has been conducted on the AV. The present article is an endeavor to review the ethanopharmacological evidence of therapeutic uses of AV in nutshell.

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Anti-Ulcer Activity of Adhatoda vasica Nees

Cited by 25 publications

References 4 publications

Anti-Ulcer Activity ofAdhatoda vasicaNees

Anti-Ulcer Activity ofAdhatoda vasicaNees

Therapeutic use of Adhatoda vasica

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