Anti-Ulcer Activity of<i>Adhatoda vasica</i>Nees

Shrivastava, Neeta; Srivastava, Anshu; Banerjee, Aryamitra; Nivsarkar, Manish

doi:10.1080/j157v06n02_04

Cited by 34 publications

(9 citation statements)

References 7 publications

(6 reference statements)

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“…Eighty percent activity was observed in ethanol-induced ulceration model. This study showed that Adhatoda vesica has anti-ulcer activity and validates its use in peptic ulcer 40 .…”

Section: Medicinal Plants Used To Treat Peptic Ulcermentioning

confidence: 95%

Complementary and Alternative Approaches to Treat Peptic Ulcer

Sultana¹,

Akram²,

Muhammad³

et al. 2014

Int. Res. J. Pharm.

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Peptic ulcer is considered as one of the most common disorder among gastrointestinal ailments all over the world which is mainly caused by Helicobacter pylori infection, abundant use of NSAIDs, excessive alcohol intake and stress etc. Treatment of peptic ulcer with synthetic drugs such as proton pump inhibitors, H2 receptor antagonists and other non-steroidal anti-inflammatory drugs reported to have adverse effects, relapses and drug interactions. Medicinal plants containing active phyto-constituents have been proven as useful source in the prevention and treatment of various diseases including gastrointestinal problems. Demands of herbal medicines are increasing in both developed and developing countries due to growing recognition of natural plants having lesser or no side effects, relatively less toxic, economical and easily available in surrounding place. Therefore, medicinal plants stand out as being exceptional for its ethnic, ethno botanical and ethno pharmaceutical uses. In this review an attempt has been made to compile some plants which may be used in treatment or prevention of peptic ulcers. This article summarizes the antacid, anti-ulcer and gastro protective properties of the most commonly available medicinal plants.

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“…Eighty percent activity was observed in ethanol-induced ulceration model. This study showed that Adhatoda vesica has anti-ulcer activity and validates its use in peptic ulcer 40 .…”

Section: Medicinal Plants Used To Treat Peptic Ulcermentioning

confidence: 95%

Complementary and Alternative Approaches to Treat Peptic Ulcer

Sultana¹,

Akram²,

Muhammad³

et al. 2014

Int. Res. J. Pharm.

View full text Add to dashboard Cite

show abstract

“…By way of intramuscular and intravenous administration, for the first 18 and 22 h, 55% of the excreted product was vasicine, whilst, on oral administration, it was 18% during the first 24 h. The leaves of A. vasica possess anti-ulcer activity, which was tested in rats. The ardusi leaves have the highest degree of anti-ulcer activity (80%) as detected in the ethanol induced ulceration model when compared to that of the actions of pylorus and aspirin [22]. The syrup made from A. vasica leaves improved symptoms of dyspepsia as well [23].…”

Section: Pharmaceutical/therapeutic Importancementioning

confidence: 97%

In vitro biotechnological advancements in Malabar nut (Adhatoda vasica Nees): Achievements, status and prospects

Gantait

Panigrahi²

2018

Journal of Genetic Engineering and Biotechnology

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Adhatoda vasica Nees, belonging to family Acanthaceae, is a well-known medicinal plant. It is endorsed for its pyrroloquinazoline alkaloids and its derivatives, such as vasicine and vasicinone. Germinating A. vasica seeds is a tedious task; on that account, vegetative propagation is the preferred method for its multiplication. For rapid and large-scale multiplication, germplasm conservation as well as secondary metabolites production, in vitro culture of A. vasica was preferred over conventional propagation by several researchers; however, some major applications of this tissue culture technique are still awaiting to undergo extensive research. The present review, for the first time, illustrates all the major achievements associated with in vitro regeneration of A. vasica , reported till date and highlights the future prospects.

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“… Anti-ulcer activity Leaves powder 500 mg/kg in 0.2 % agar Ethanol induced and Pylorus ligation plus aspirin-induced rats The ethanol-induced ulceration model had the highest level of activity (80 %). [ 85 ] 7. Allelopathic activity Fresh and dried aqueous extract of leaves 60 % concentration of extract Seeds of Capsicum annum L. Dry aqueous extract was found more phytotoxic than fresh aqueous extract.…”

Section: Pharmacologymentioning

confidence: 99%

Exploring the pharmacological and chemical aspects of pyrrolo-quinazoline derivatives in Adhatoda vasica

Khandelwal,

Wadhwani,

Rao

et al. 2024

Heliyon

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Anti-Ulcer Activity ofAdhatoda vasicaNees

Cited by 34 publications

References 7 publications

Complementary and Alternative Approaches to Treat Peptic Ulcer

Complementary and Alternative Approaches to Treat Peptic Ulcer

In vitro biotechnological advancements in Malabar nut (Adhatoda vasica Nees): Achievements, status and prospects

Exploring the pharmacological and chemical aspects of pyrrolo-quinazoline derivatives in Adhatoda vasica

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