Abstract:Abstract:The synthesis was performed using 5-methyluracil mono-and bis-derivatives with the halogencontaining pharmacophore groups in the composition of molecules; their physiochemical and biological properties were studied. These reactions are a typical example of substitution reactions on heteroatom N (1) of uracil molecule using as the second component the reaction of halothane-the known inhaled anesthetic. The reactions were carried out in a solvent system: benzene-dimethyl formamide and diethyl ether, und… Show more
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