Anti‐Infectious Surfaces Achieved by Polymer Modification

Abstract

This review article presents the potential strategies of material surface modification by using polymeric approaches to design anti-infectious materials. Supported by recent examples such as utilizing either microbe lethal or repelling properties, different strategies to the design of antimicrobial surfaces are reviewed. The deposition strategies for creating polymer modified antibacterial surfaces are described

Novel biocidal N-halamine plastic based on poly(vinyl chloride): Preparation and characteristics

“…Pathogens can exist in various surroundings for a long 14 time without triggering any reactions. For example, Gram-negative 15 bacteria, living on clothes of hospital staff can survive from 1 h to 16 90 days, and fungi-from one day to several weeks [1,2]. In 17 appropriate humidity and temperature, they may cause an 18 infection of an organism with reduced resistance.…”

“…322 Thus, the material obtained has a microbe lethal surface. 323 The bioactivity of N-halamine compounds can be explained by 324 their interactions with cellular receptors leading to microbial cell 325 activity inhibition or inactivation [16]. It is generally accepted that 326 the biocidal properties of N-halamines are a result of the direct 327 transport of Cl + into bacteria cells ( [13] and references cited 328 therein).…”

Surface Modification of Polymer Substrates for Biomedical Applications

“…Any kind of surface modification will lead to a change of surface chemistry and morphology, which will in turn, more or less noticeably, affect the optical, mechanical, tribological, adhesive, electrical and various other properties of the modified substrate. Such changes should occur only in a small depth away from the surface, while the bulk of the modified polymer and therefore also its properties should remain unaltered [18]. …”

Nontoxic, Hydrophilic Cationic Polymers—Identified as Class of Antimicrobial Polymers

“…Antimicrobial polymers have been considered as alternative to common biocides for quite some time . These macromolecules are either used as disinfectants or for synthesizing antimicrobial, contact‐active surfaces . They can be categorized by biocide‐releasing polymers, macromolecules that are consisting of polymerized biocides, and biocidal polymers that are only active as polymer chain .…”