Anti-obesity natural products and gut microbiota

Phenolamide extract of apricot bee pollen alleviates glucolipid metabolic disorders and modulates the gut microbiota and metabolites in high-fat diet-induced obese mice

“…In recent years, there has been accumulating evidence showing that the gut microbiota is a potential factor in metabolic syndromes such as obesity and also a therapeutic target for natural products. 45 The effect of PAE intervention on the gut microbiota of HFD-fed mice was investigated by high-throughput sequencing of the V3 and V4 regions of the 16S rRNA gene in fecal samples. Based on 97% sequence similarity criteria, 882, 656, 718 and 883 OUTs were identified in the NC, HFD, LD, and HD groups, respectively (Fig.…”

Eugenol, A Major Component of Clove Oil, Attenuates Adiposity, and Modulates Gut Microbiota in High‐Fat Diet‐Fed Mice

“…[7] Hence, it is of great value to explore more effective and safe anti-obesity agents, especially from food and other natural products. [8] Gut microbiota is a population of microorganisms that live in the digestive tracts. The gut microbiota is called the second genome, which contains 10 times more microbial cells than body cells.…”

The different effects of psyllium husk and orlistat on weight control, the amelioration of hypercholesterolemia and non-alcohol fatty liver disease in obese mice induced by a high-fat diet

“…13 Rebalancing of the intestinal microbiota can help to treat obesity. 14 Dietary fibre has been proven to be beneficial for those with obesity, as it has prebiotic characteristics, which affect the gut microbiota. 15 Our preliminary findings showed both psyllium husk and orlistat aided in weight loss when combined with diet control and increased exercise.…”