Anti-Microbial Activities of Turmeric and Ginger on Bacterial Isolates of Normal Skin Flora

Samuel-Penu, Barisi; Baridakara, Sordum Catherine

doi:10.9734/jamb/2021/v21i330336

Cited by 2 publications

(1 citation statement)

References 9 publications

(9 reference statements)

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“…In a study carried out by Samuel-Penu and Baridakara [56], it was observed that the aqueous extract of ginger (Zingiber officinale) did not inhibit any growth of bacteria both at 100 and 50% concentrations while the ethanolic extract of ginger inhibited and a zone diameter of 11 mm was recorded both for Staphylococcus epidermidis and Bacillus sp. at the 100% concentration.…”

Section: Escherichia Coli and Staphylococcus Aureusmentioning

confidence: 99%

Evaluation of Secondary Metabolites Profiling of Ginger (Zingiber officinale Roscoe) Rhizome using GC-MS and Its Antibacterial Potential on Staphylococcus aureus and Escherichia coli

Momoh

Olaleye

2022

MRJI

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Objective: Ginger (Zingiber officinale Roscoe) rhizome is a well-known food spice and flavoring ingredient with wide range of medicinal properties. The rhizome of ginger consists of unique secondary metabolites compounds. The study evaluates the secondary metabolites profiling of ginger (Zingiber officinale Roscoe) rhizome using Gas Chromatography-Mass Spectrometry (GC-MS) and its antibacterial potential on Staphylococcus aureus and Escherichia coli. Methodology: The GC-MS and phytochemical screening of the aqueous ginger (Zingiber officinale Roscoe) rhizome extract were determined using standard procedures. Antibacterial activities were determined by agar well diffusion methods. The minimum inhibitory concentrations (MIC) were determined using standard procedure. Results: The result of the GC-MS analysis shows that thirty six compounds were identified in the ginger (Zingiber officinale Roscoe) rhizome using GC-MS analysis with tridecane with molecular formula of C13H28 being the most abundant with peak area of 16.94% and retention time of 12.849. The phytochemical screening shows that the plant contains saponins, alkaloids, glycoside, simple phenolics, tannins, flavonoids carbohydrates and reducing sugar. The study shows that at 250 mg/ml, the aqueous ginger extract exhibited little or no response with zone of inhibition of 9.85±0.39 and 8.19±1.33 mg/ml against Staphylococcus aureus and Escherichia coli respectively. The extract exhibited weak response antibacterial activity against E. coli and moderate response against S. aureus with zone of inhibition of 13.62±2.03 and 16.73±1.83 at 500 mg/dl respectively. Augmentin showed moderate and strong response with zone of inhibition of 17.23±1.67 and 21.13±1.34 mg/ml against E. coli and S. aureus at concentration of 7.50 mg/ml respectively. At 15 mg/ml, augmentin showed strong response with zone of inhibition of 23.00±2.88 mg/ml against E. coli and potent response with zone of inhibition of 30.50±2.64 mg/ml against S. aureus. The Minimum inhibitory concentration (MIC) values for the aqueous ginger are 125 and 250 mg/ml for S. aureus and E. coli and 7.81 and 15.63 for augmentin solution for the sane organisms respectively. Conclusions: The aqueous ginger (Zingiber officinale Roscoe) rhizome contains secondary metabolites and possesses poor antibacterial activity against Staphylococcus aureus and Escherichia coli and may prevent pathogenic diseases caused by these organisms.

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Section: Escherichia Coli and Staphylococcus Aureusmentioning

confidence: 99%

Evaluation of Secondary Metabolites Profiling of Ginger (Zingiber officinale Roscoe) Rhizome using GC-MS and Its Antibacterial Potential on Staphylococcus aureus and Escherichia coli

Momoh

Olaleye

2022

MRJI

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Pharmacological Effects of Curcuma Longa and Its Bioactive Constitute Curcumin

Koser

Abbas

Rizwan

et al. 2022

PBMJ

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Curcuma longa (Turmeric) belongs to the family Zingeberaceae, commonly used as a spice, pigment and additive also are one of the most important ingredients in the Indian subcontinent. In recent years’ research revealed several important functions of it. Among those being investigated is Turmeric. The aim of this review is to summarize the chemistry, referend, formulations of curcminoids and their biological activities and provides an update mainly on the pharmacological activities of the Turmeric, its extracts and credible medicinal applications of Turmeric, along with their safety evaluation. Its most important active ingredient is curcuminoids. Which are phenolic compounds and volatile oils being also present in turmeric are known for their functional and nutraceutical properties. Various preclinical cell culture and animal studies suggest that curcuminoids have extensive biological activity as antioxidants, neuroprotective, antitumor, anti-inflammatory, anti-acidogenic, radioprotective, and arthritis. Different clinical trials also suggest a potential therapeutic role for curcuminoids in numerous chronic diseases like colon cancer, lung cancer, breast cancer, inflammatory bowel diseases. Nowadays, several drugs have been developed deriving from traditional products, and current drug research is actively investigating the possible therapeutic roles of many Ayurvedic and Traditional Indian medicinal therapies. Health benefits attributed to curcuminoids have resulted in their comprehensive utilization in food and pharmaceutical formulations.

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Anti-Microbial Activities of Turmeric and Ginger on Bacterial Isolates of Normal Skin Flora

Cited by 2 publications

References 9 publications

Evaluation of Secondary Metabolites Profiling of Ginger (Zingiber officinale Roscoe) Rhizome using GC-MS and Its Antibacterial Potential on Staphylococcus aureus and Escherichia coli

Evaluation of Secondary Metabolites Profiling of Ginger (Zingiber officinale Roscoe) Rhizome using GC-MS and Its Antibacterial Potential on Staphylococcus aureus and Escherichia coli

Pharmacological Effects of Curcuma Longa and Its Bioactive Constitute Curcumin

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