Anti-inflammatory effect of rutin on rat paw oedema, and on neutrophils chemotaxis and degranulation

In vivoanti-inflammatory properties of aerial parts ofNasturtium officinale

“…Rutin, chlorogenic, and caffeic acids were quantified in the extract (Boligon et al, 2013). Furthermore, antiinflammatory effects of three indicated components have been reported (Chagas-Paula et al, 2011;Gamaro et al, 2011;Selloum et al, 2003). Therefore, these phenolic components in the pant could play an important role in its anti-inflammatory activity.…”

Suppressive Effects of Natural and Synthetic Agents on Dextran Sulfate Sodium-induced Interleukin-1β Release from Murine Peritoneal Macrophages

“…Tel: +81-75-753-6281; Fax: +81-75-753-6284; E-mail: ohigashi@kais.kyoto-u.ac.jp Abbreviations: IL, interleukin; UC, ulcerative colitis; CD, Crohn's disease; IBD, inflammatory bowel disease; TNF, tumor necrosis factor; DSS, dextran sulfate sodium; pM, peritoneal macrophages; NAC, N-acetylcysteine; BHA, butylated hydroxyanisole; COX, cyclooxygenase; iNOS, inducible nitric oxide synthase; DMSO, dimethylsulfoxide; BITC, benzyl isothiocyanate; PPAR, peroxisome proliferator-activated receptor; NO, nitric oxide; IR, inhibitory rate; CV, cell viability; MTT, 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide; EGCG, (À)-epigallocatechin gallate rutin and gallic acid (natural compounds, each at 100 M), were highly suppressive (IRs ¼ 72:8, 67.8 and 58.9%, and 79.3, 68.6 and 64.7%, respectively, P < 0:01 each). Our data may provide some insight into the molecular mechanisms by which -tocopherol 12) and rutin 13) suppress inflammation-related biological phenomena. The synthetic compounds, 1400W, meloxicam, bezafibrate and acetylsalicylic acid (at 100 M), and benzyl isothiocyanate (BITC), (À)-catechin and silymarin (natural compounds at 100 M) showed moderate inhibition (IRs ¼ 45:7, 38.4, 35.3 and 29.8%, and 53.9, 52.3 and 21.8%, respectively, P < 0:01 or P < 0:05).…”

Review of beneficial and remedial aspects of Cardiospermum halicacabum L.

“…These results suggest that ethanolic extract act as a natural antioxidant and anti-inflammatory mediator (Huang et al, 2010). Lately, the anti-inflammatory role of rutin has been recognized (Selloum et al, 2003;Babu and Krishnakumari, 2005).…”

“…In small reproduction places of restricted size around human residences this extract might be applied directly as adulticidal mediator (Selloum et al, 2003). The methanolic and benzene extract of the herb produced 100% mortality against Culex quinquefasciatus while A. aegypti achieved the absolute ovicidal activity for the methanolic extract.…”