Anti-inflammatory and gut microbiota modulatory effects of polysaccharides from Fuzhuan brick tea on colitis in mice induced by dextran sulfate sodium

Abstract

In this study, the effects of crude Fuzhuan brick tea polysaccharide (CFBTPS) and purified fraction (FBTPS-3) on colitis induced by dextran sulfate sodium (DSS) in mice were investigated. Both CFBTPS...

Fu Brick Tea Polysaccharides Prevent Obesity via Gut Microbiota-Controlled Promotion of Adipocyte Browning and Thermogenesis

“…Fu brick tea was thoroughly crushed and was passed through a 60-mesh screen. The extraction method of FBTP was developed according to the reported method. , The crushed sample was mixed with 95% ethanol (1:20, w/v) and was properly stirred for 4 h at 70 °C to degrease. The degreased sample was then mixed with 2000 mL of water at 80 °C with sufficiently stirring for 4 h, and the supernatant was collected after centrifugation (4000 g , 5 min).…”

Chemical components of Fu brick tea and its potential preventive effects on metabolic syndrome

“…FBT polysaccharide can improve IBD by repairing the intestinal barrier. Zeng and Bai et al studied the anti-inflammatory activity of crude and purified FBT polysaccharide on mice with colitis induced by sodium dextran (Bai et al, 2022;Zeng et al, 2022). It was found that the expression of lipocalcemin-2 was significantly reduced in colitis.…”

“…And the water extracts could also reduce the levels of total cholesterol, serum triacylglycerol, and low‐density lipoprotein. Thus, FBT extracts have significant effects on weight loss and blood lipid reduction (Li, Liu, et al., 2013 ; Zeng et al., 2022 ; Zhou, Tian, et al., 2021 ).…”

Incidental nanoparticles in black tea alleviate DSS-induced ulcerative colitis in BALB/c mice

“…16 When orally administered at a rather high dosage (200 mg per kg body weight per day for 7 days), the purified polysaccharides from a dark tea (brick tea) attenuated colitis in mice, suppressed pro-inflammatory cytokines, increased the expression of cell junction proteins, and restored the homeostasis of the gut microbiota. 17 The prebiotic effects of tea components include increasing the diversity and optimizing the structure of the gut microbiota, and enriching short-chain fatty acids. 18,19 The rich content of amphiphilic molecules in tea infusion facilitates the self-assembly of colloidal particles.…”

“…16 When orally administered at a rather high dosage (200 mg per kg body weight per day for 7 days), the purified polysaccharides from a dark tea (brick tea) attenuated colitis in mice, suppressed pro-inflammatory cytokines, increased the expression of cell junction proteins, and restored the homeostasis of the gut microbiota. 17 The prebiotic effects of tea components include increasing the † Electronic supplementary information (ESI) available. See DOI: https://doi.org/ 10.1039/d3fo00641g a School of Chemical Engineering and Technology, Tianjin University, China b Zhe Jiang Institute of Tianjin University, Shaoxing, China diversity and optimizing the structure of the gut microbiota, and enriching short-chain fatty acids.…”