Anti‐Helicobacter pylori Activities of Six Iranian Plants

Nariman, Farahnaz; Eftekhar, Fereshteh; Habibi, Zohreh; Falsafi, Tahereh

doi:10.1111/j.1083-4389.2004.00211.x

Cited by 62 publications

(51 citation statements)

References 21 publications

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“…10,13 In three separate studies performed in Iran, clarithromycin resistance of H. pylori isolates were reported 14.5, 21 and 23% of the isolates. 7,14,15 In our study, only 9.4% of the isolates were resistant to clarithromycin. Since high cost of clarithromycin limits the use of this drug in Iran, Þ nding such resistant isolates may be partially explained by the primary resistance of H. pylori to clarithromycin.…”

Section: Discussioncontrasting

confidence: 49%

“…8,9 The World-wide prevalence of resistance to amoxicillin is 0-41%. 10,14,16 In the two previous studies in Iran, investigators reported 7 and 27% amoxicillin resistance among H. pylori isolates. 7,15 In the present study, the amoxicillin resistance was found to be 20.8% of isolates.…”

Section: Discussionmentioning

confidence: 97%

“…9,10,13 In the three studies carried out by Siavoshi et al, 7 Nariman et al 14 and FalsaÞ et al, 15 in Tehran, Iran, the prevalence of metronidazole resistance were reported to be 37.5, 72 and 72-79%, respectively. We found 72.6% resistance among H. pylori isolates in Shiraz southern Iran.…”

Section: Discussionmentioning

confidence: 97%

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Antimicrobial susceptibility testing of Helicobacter pylori to selected agents by agar dilution method in Shiraz-Iran

Kohanteb¹,

Bazargani²,

Saberi-Firoozi³

et al. 2007

Indian J Med Microbiol

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Section: Discussioncontrasting

confidence: 49%

Section: Discussionmentioning

confidence: 97%

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Antimicrobial susceptibility testing of Helicobacter pylori to selected agents by agar dilution method in Shiraz-Iran

Kohanteb¹,

Bazargani²,

Saberi-Firoozi³

et al. 2007

Indian J Med Microbiol

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“…However, the methanol extract showed no inhibition at MIC 50 against H. pylori PE 252C. The MIC results confirm earlier findings by Nariman et al (2004) who documented MIC ranges of 0.0037 to 2 mg/mL. Also, MIC values of 0.0625 to 0.5 mg/mL have been documented for East African medicinal plants against similar bacterial pathogens (Fabry et al, 1996).…”

Section: Discussionsupporting

confidence: 88%

Bioactivity of Hydnora africana on selected bacterial pathogens: Preliminary phytochemical screening

Nethathe¹,

Ndip²

2011

Afr. J. Microbiol. Res.

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Medicinal plants contain a variety of chemical substances with important therapeutic properties that can be utilized in the treatment of human diseases. Hydonora africana is used in folklore remedies for the treatment of diarrhoea, dysentery, kidney and bladder complaints among other ailments; hence we assessed the in vitro antimicrobial activity of this plant against three bacterial species (Helicobacter pylori ATCC 43526, Helicobacter pylori PE 252C, Staphylococcus aureus NCTC 6571 and Aeromonas hydrophila ATCC 35654). The agar well diffusion method was used to determine the susceptibility of bacterial strains to crude extracts of the plant. The minimum inhibitory concentration (MIC 50 ) and minimum bactericidal concentration (MBC) of the active crude extracts were determined by the microdilution test. Ciprofloxacin (0.0125 mg/mL) was used as positive control. The presence of phytochemicals was also assessed using standard methods. Results were analyzed statistically by the one-way ANOVA test. Hydnora africana demonstrated antimicrobial activity against all the organisms with a mean zone diameter of inhibition ranging from 0 to 22 mm. The MIC 50 of the extracts ranged from 0.078 to 2.5 mg/mL and MBC ranged from 0.78 to 25 mg/mL. Phytochemical assay revealed the presence of alkaloids, tannins, flavonoids, saponins and steroids in the extracts. It is concluded that H. africana may contain compounds with therapeutic activity.

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“…The inhibitory effect of G. glabra on Helicobacter pylori was studied in-vitro and indicated that it can have effects similar to those of metronidazole (15). Another research also indicated the inhibitory effects of G. glabra extract on H. pylori (16). Some Glycyrrhiza species, e g, G. glabra, inhibit the growth of some Gramnegative bacteria such as Shigella spp.…”

Section: Discussionmentioning

confidence: 99%

Efficacy of Some Medicinal Plants Extracts for Potential Antifungal Activity

Abkhoo

Jahani

2016

Int J Infect

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Background: Peganum harmala, Glycyrrhiza glabra, Mentha spicata and Rosmarinus officinalis are often used in traditional medicine. Objectives: The current study aimed to screen the antifungal activity of ethanolic extracts of P. harmala, G. glabra, M. spicata and R. officinalis leaves collected from Sistan region, Iran against Fusarium oxysporum. Methods: Minimal inhibitory concentration (MIC) and minimum fungicidal concentration (MFC) of herbal extracts were determined. Results: Of the total herbal extracts, four showed fungistatic activities and two showed fungicidal activities. MIC values, ranged 6.25 -50 ppm and MFC values, ranged 12.5 -100 ppm. The ethanolic extract of G. glabra had the lowest MIC (6.25 ppm); while the ethanolic extract of R. officinalis had the highest MIC (50 ppm). Minimum bactericidal concentration (MBC) of the alcoholic extract of G. glabra showed the highest efficiency against F. oxysporum at the low value of 12.5 ppm. Conclusions:The results of the study showed the antifungal activity of medicinal plants against F. oxysporum. Especially, the bioactive compounds of G. glabra were effective to inhibit the growth of F. oxysporum.

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Anti‐Helicobacter pylori Activities of Six Iranian Plants

Abstract: Due to the rise in antibiotic resistance, new sources of anti-H. pylori drugs are needed. The use of medicinal plants and/or their chemical components may have potential benefit in eradicating such problems.

Cited by 62 publications

References 21 publications

Antimicrobial susceptibility testing of <i>Helicobacter pylori </i>to selected agents by agar dilution method in Shiraz-Iran

Antimicrobial susceptibility testing of <i>Helicobacter pylori </i>to selected agents by agar dilution method in Shiraz-Iran

Bioactivity of Hydnora africana on selected bacterial pathogens: Preliminary phytochemical screening

Efficacy of Some Medicinal Plants Extracts for Potential Antifungal Activity

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