Anti-Escherichia coli activity of extracts from Schinus terebinthifolius fruits and leaves

Abstract

Ethanol extracts obtained from Schinus terebinthifolius Raddi fruits and leaves were active against Escherichia coli with MIC of 78 μg mL for both extracts. Phytochemical analyses revealed a major presence of phenolic acids, tannins, fatty acids and acid triterpenes in the leaves and phenolic acids, fatty acids, acid triterpenes and biflavonoids in the fruits. Major compounds isolated from the plant, such as the acid triterpene schinol, the phenolic acid derivative ethyl gallate and the biflavonoids agathisflavone and tetrahydroamentoflavone, showed very little activity against E. coli. Bioautography of the ethanol extracts on silica gel plate showed inhibition zones for E. coli. They were removed from the plate and the compounds identified as a mixture of myristic, pentadecanoic, palmitic, heptadecanoic, stearic, nonadecanoic, eicosanoic, heneicosanoic and behenic fatty acids.

Microbiological quality, chemical profile as well as antioxidant and antidiabetic activities of Schinus terebinthifolius Raddi

“…In traditional medicine, this plant is used to treat skin wounds and ulcers, tumors, diarrhea, arthritis as well as urinary and respiratory tract infections (Brandão et al, 2006). Various pharmacological activities have been described for this plant, including antimicrobial (Silva et al, 2017a), antiulcerogenic (Carlini et al, 2010), anticancer (Silva et al, 2017b), antihistamine (Nunes-Neto et al, 2017), antihypertensive (Glória et al, 2017), antihyperalgesic (Piccinelli et al, 2015), wound healing (Estevão et al, 2017), anti-inflammatory (Silva et al, 2017b) and antioxidant (Rocha et al, 2017) activities in different models.…”

Preparation of glass-ionomer cement containing ethanolic Brazilian pepper extract (Schinus terebinthifolius Raddi) fruits: chemical and biological assays

“…Among the suggested compounds, gallic acid, quercetin and quercitrin have already been reported for Schinus lentiscifolius that showed a broad spectrum of antimicrobial activity 62 . In this same way, ethanolic extract from fruits and leaves of S. terebinthifolius showed high potential against E. coli and this data can be related to the presence of ethyl gallate, which was one of the main compounds reported 63 . Other proposed substances, such as myricitrin 64 , catechin 3-O-gallate 65 , avicularin 66 , and amentoflavone 67 also demonstrated action against microorganisms.…”

Evaluation of antimicrobial and synergistic effects of some medicinal plant extracts on antimicrobial resistant organisms

“…Previous studies reported the capacity of the ethanol extract and essential oil of leaves of Schinus terebinthifolius to inhibit the growth of S. aureus [24], P. aeruginosa [23], Yersinia enterocolitica, E. coli, Acinetobacter calcoaceticus, K. pneumoniae and Bacillus subtilis [23]. Meanwhile, Jessica and colleagues [25] described an excellent antimicrobial activity of ethanolic extract of Schinus terebinthifolius leaves against E. coli with no inhibitory effect on C. albicans.…”