Anti-Hyperglycemic and Anti-Hyperlipidemic Potentials of Methanol Leaf Extracts of Aframomum melegueta and Piper guineense

Morakinyo, Adetoun; Oyedepo, Temitope A.; Babarinde, Olufolarin; Adelowo, Joy Motunrayo; Adepoju, Ayodeji Emmanuel; Oyedapo, O. O.

doi:10.9734/ejmp/2019/v27i130106

Cited by 2 publications

(1 citation statement)

References 6 publications

(7 reference statements)

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“…This antihyperglycemic effect is thought to be caused by the combination of eugenol, limonene, α‐pinene, and β‐pinene in these oils (Adefegha et al., 2017 ). In diabetic rats, A. melegueta methanolic extract has also been shown to control hyperglycemia (Elizabeth et al., 2019 ). Non‐volatile phytochemicals such as paradols, shogaols, and gingerols are present in ginger (Ali et al., 2008 ).…”

Section: African Diet and Management Of Diabetesmentioning

confidence: 99%

Functional foods of sub‐Saharan Africa and their implications in the management of type 2 diabetes: A review

Matsinkou Soh,

Ngaha Damndja,

Njintang Yanou

2023

Food Science & Nutrition

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Throughout the world, the prevalence of metabolic diseases in general and type 2 diabetes (T2DM) in particular is constantly growing, and sub‐Saharan Africa (SSA) is not spared. The use of functional foods is a more practical option among the different approaches used in the management of T2DM owing to the fact that they are relatively less costly, safer, and more accessible. In addition to their low glycemic index just like foods currently used to manage diabetes, functional foods contain bioactive compounds such as polyphenols, dietary fibers, saponins, and peptides. They are so named because they have additional health advantages beyond their basic nutritional worth. Bioactive compounds can be found in a variety of SSA plant‐based foods, such as spices, fruits, vegetables, legumes, starchy foods, prepared foods, mixed foods, and prepared dishes. The goal of this review is to highlight some of the investigations into the effectiveness of local food and their antidiabetic mechanisms that have been studied in various SSA regions. Using the literature review as a basis, the authors state that SSA foods are rich in various bioactive compounds capable of regulating blood sugar through enhanced glucose tolerance, antioxidant effects, insulin sensitivity, and inhibition or activation of some key enzymes of the glucose metabolism that are linked to the prevention and management of T2DM. Many of the cited findings are preliminary, obtained from cell and preclinical studies, and therefore other studies need to be done to demonstrate the full potential of these foods to serve as bases for dietary guidelines.

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Section: African Diet and Management Of Diabetesmentioning

confidence: 99%

Functional foods of sub‐Saharan Africa and their implications in the management of type 2 diabetes: A review

Matsinkou Soh,

Ngaha Damndja,

Njintang Yanou

2023

Food Science & Nutrition

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Ethnomedicinal Knowledge of Plants Used in Nonconventional Medicine in the Management of Diabetes Mellitus in Kinshasa (Democratic Republic of the Congo)

Chiribagula Valentin,

Ndjolo Philippe,

Mboni Henry

et al. 2023

Evidence-Based Complementary and Alternative Medicine

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Background. People with diabetes, herbalists, and traditional medicine practitioners (TMPs) from Kinshasa use plants to treat diabetes, but no study has inventoried the plants used by these populations. The present study was conducted to identify the plants used in Kinshasa to treat diabetes mellitus. Methods. The survey conducted in the form of a semistructured interview between March 2005 and August 2006 made it possible to collect ethnobotanical information from people with diabetes (n = 126), herbalists (n = 80), and TMPs (n = 120). Results. The 326 subjects consulted (sex ratio M/F = 0.6, age 51 ± 7 years, and experience: 17 ± 5 years) provided information on 71 plants, most of which are trees (35%), belonging to 38 families dominated by Fabaceae (19.7%) and indicated in 51 other cases of consultation dominated by malaria (12%). From these 71 plants derived, 86 antidiabetic recipes were administered orally, where the leaf is the most used part (>50%) and the decoction (>46%) is the most common mode of preparation. This study reports for the first time the antidiabetic use of 11 species, among which Tephrosia vogeliiX (0.08), Chromolaena corymbosaX (0.06), and Baphia capparidifoliaX (0.06) present the highest consensus indexes (CI) and Marsdenia latifoliaW (UVp = 0.08) and Rauvolfia manniiX (UVp = 0.06) present the highest UVs. Conclusion. The results show that Kinshasa people treat diabetes using several plants. Some are specific to the ecological environment; others are used in other regions. Pharmacological studies are underway to assess the therapeutic efficacy of these plants.

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Anti-Hyperglycemic and Anti-Hyperlipidemic Potentials of Methanol Leaf Extracts of Aframomum melegueta and Piper guineense

Cited by 2 publications

References 6 publications

Functional foods of sub‐Saharan Africa and their implications in the management of type 2 diabetes: A review

Functional foods of sub‐Saharan Africa and their implications in the management of type 2 diabetes: A review

Ethnomedicinal Knowledge of Plants Used in Nonconventional Medicine in the Management of Diabetes Mellitus in Kinshasa (Democratic Republic of the Congo)

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