Anti-histaminic and bronchodilatory activities of aqueous and methanol extracts of &lt;i&gt;Calotropis procera&lt;/i&gt; (Ait) R.Br. root bark on allergic asthma in rodents

Aliyu, Ibrahim; Zezi, Abdulkadir Umar; Magaji, Mohammed Garba; Abdu-Aguye, I; Ibrahim, Z. Y. Y.; Atiku, I.; Muntaka, Abdulrahman

doi:10.4314/jpb.v14i2.4

Cited by 4 publications

(2 citation statements)

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“…But aqueous extract failed to produce any effective result in in-vivo test whereas methanol extract significantly showed inhibitory action in the in-vivo test. The study suggested that Calotropis procera plant can be used in allergic conditions like asthma [110].…”

Section: Anti-asthmaticmentioning

confidence: 99%

Calotropis procera (Arka): A Tribal Herb of Utmost Significance

Kumari¹,

Chaudhary²

2021

Int. j. res. appl. sci. biotechnol.

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Nature has gifted humans a vast variety of medicinal plants, which are the rich source of bioactive compounds. Calotropis procera is an important medicinal plant that belongs to the family asclepiadaceae. It is commonly known as madar and milkweed plant in english and arka in hindi. It is mostly found in the tropics of asia and africa. Calotropis procera is a highly valued plant in the folk medication system. Each part of the plant is richly endowed with diverse nature of phytochemical constituents like alkaloids, proteins, vitamins, carbohydrates, saponins, terpenes, and flavonoids, etc. These phytochemicals are significantly associated with various therapeutic and pharmacological properties such as anti-microbial, anti-oxidant, anti-inflammatory, anti-ulcer, antifertility, anti-diarrheal, and spasmolytic. In this review article, the therapeutic and pharmacological value of this important plant has been summarized along with its utilization in the folklore and ayurvedic medicinal system.

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Section: Anti-asthmaticmentioning

confidence: 99%

Calotropis procera (Arka): A Tribal Herb of Utmost Significance

Kumari¹,

Chaudhary²

2021

Int. j. res. appl. sci. biotechnol.

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“…Calotropis procera Linn (Vellerukku) having Bitter (Kaippu), Pungent (Karppu), Sweet (Madhuram) tastes, Hot potency (Vetpam), Pungent on division (Karppu) (Thiyagarajan, 2013) and also hold the Anti-histaminic, Bronchodilator, Anti-Asthmatic, Antimicrobial (Antifungal/ Antibacterial/ Antiviral), Anti -Inflammatory, Immunological effects, Anti-oxidant properties (Kumar et al, 2005;Yesmin et al, 2008;Kumar and Roy, 2009;Bagherwal, 2011;Mako et al, 2012;Halu and Vidyasagar, 2012;Bouratoua et al, 2013;Aliyu et al, 2017;Beniwal and Mittal, 2022). By virtue of these properties, Swasakasa nei is useful in Karappan pitham.…”

Section: Same Medicines Continuedmentioning

confidence: 99%

Management of Eosinophilia With Elevated Serum IgE (Karappan Pitham) Patient Through Traditional Siddha Herbal Drug Swasakasa Nei – A Case Report

et al. 2023

Intern. J. Zool. Invest.

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Eosinophilia is one of the common laboratory findings of who have history of dust and food allergy with lingering symptoms such as itching, sneezing with rhinitis, cough, dyspnoea, chest discomfort, wheezing and hyperpigmentation in some cases. This can be correlated with Karappan pitham by Siddha point of view. Conventional treatment may control the eosinophilia and provide symptomatic relief at the time, but relapses are often observed. A 24-year-old male patient has been diagnosed as eosinophilia with elevated serum IgE based on his presenting complaints. He was given Swasakasa nei (Internal) and Kungiliya vennai (External) as an intervention. After completion of ten weeks of the treatment, the patient got complete symptomatic relief and no symptoms was relapsed during the follow-up period of four weeks and patient's increased absolute eosinophil count 860 cells/cumm and serum IgE 5284.5 IU/ml turned down to 210 cells/cumm, and 3273.8 IU/ml, respectively. The observations infer that the Swasakasa nei has significant benefits in eosinophilia with elevated serum IgE patient. This shows that there is a wide scope to explore the variety of imperative medicines present in Siddha pharmacopoeia, which can be used more rationally to treat various allergic conditions like allergic asthma, hay fever, allergic eczema etc.

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Chemistry, Biological Activities, and Uses of Calotropis Latex

Bankole

Thiemann

2022

Reference Series in Phytochemistry

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Anti-histaminic and bronchodilatory activities of aqueous and methanol extracts of <i>Calotropis procera</i> (Ait) R.Br. root bark on allergic asthma in rodents

Cited by 4 publications

References 0 publications

Calotropis procera (Arka): A Tribal Herb of Utmost Significance

Calotropis procera (Arka): A Tribal Herb of Utmost Significance

Management of Eosinophilia With Elevated Serum IgE (Karappan Pitham) Patient Through Traditional Siddha Herbal Drug Swasakasa Nei – A Case Report

Chemistry, Biological Activities, and Uses of Calotropis Latex

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