Anti-Fatigue and Anti-Hypoxic Effects of Lycium barbarum Polysaccharides

Wu, Ming Chang; Guo, Liquan

doi:10.2991/aeece-15.2015.137

Cited by 4 publications

(2 citation statements)

References 9 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The mechanism of its hypoglycemic effect remains controversy. Previous studies proved that goji extract could increase the liver and muscle glycogen which is the best storage form of glucose [41] . Moreover, LB polysaccharides could enhance the glucose transport in skeletal muscle by facilitating the translocation of glucose transporter 4 (the main insulin sensitive glucose transporter) from the cytoplasm to the cell membrane [42] .…”

Section: Discussionmentioning

confidence: 96%

Can Goji Berry Extract Attenuate Pancreatic Structural Changes Induced by Patulin Toxin in Male Albino Rats?

Soliman

2017

Egyptian Journal of Histology

View full text Add to dashboard Cite

Introduction: Patulin is considered the most common mycotoxins in moldy fruits especially apples and its products like juice and compote. Goji berry (lycium barbarum fruit) is a traditional Chinese herb. It has several biological activities as antioxidant, anti-aging and hypoglycemic properties. Aim: To demonstrate the toxic effect of patulin on the pancreatic tissue and to evaluate the possible role of goji extract. Material and Methods: Forty adult male albino rats were divided equally into four groups. Group I served as the control group. Group II received subcutaneous injection of 2 ml/kg/day goji extract for four weeks. Group III received subcutaneous injection of patulin 0.2 mg/kg/day for four weeks. Group IV received patulin and goji extract with the same previous doses for four weeks. Histological and immunohistochemical studies were done. Results: The administration of patulin led to degenerative changes in the pancreas. There was a significant increase in caspase-3 positive cells in both acini and islets of Langerhans. Ultrastructural examination revealed heterochromatic nuclei, cytoplasmic vacuoles and few secretory granules in acinar cells. The β cells of the islets exhibited a significant decrease in the area percentage and intensity of insulin positive cells. Goji extract could effectively improve these histological changes. Conclusion: Patulin toxicity affected both exocrine acini and β cells of islets of Langerhans. The goji extract had a protective role on this toxicity.

show abstract

Section: Discussionmentioning

confidence: 96%

Can Goji Berry Extract Attenuate Pancreatic Structural Changes Induced by Patulin Toxin in Male Albino Rats?

Soliman

2017

Egyptian Journal of Histology

View full text Add to dashboard Cite

show abstract

“…Phytochemical studies have also indicated that the various biological activities of Lycium species are related to their richness in different classes of compounds (e.g., polysaccharides, carotenoids, flavonoids, alkaloids, amides, and terpenoids, among others) (Yao et al, 2011;Qian et al, 2017). Moreover, it has been reported that extracts of plant-based metabolites, especially polysaccharides and vitamins, promote anti-aging, eyesight improvement, and anti-fatigue effects (Wu and Guo, 2015;Yao et al, 2017).…”

Section: Gc-ms Metabolic Profiling Analysismentioning

confidence: 99%

Distinguishing features of Lycium L. species (family Solanaceae) distributed in Egypt based on their anatomical, metabolic, molecular, and ecological characteristics

et al. 2023

View full text Add to dashboard Cite

Among the 70–80 species of the genus Lycium (family Solanaceae) disjunctly distributed around the world, only three are frequently distributed in different locations in Egypt. Due to the morphological similarities between these three species, there is a need for alternative tools to distinguish them. Thus, the objective of this study was to revise the taxonomic features of Lycium europaeum L., Lycium shawii Roem. & Schult., and Lycium schweinfurthii var. aschersonii (Dammer) Feinbrun in consideration of their anatomical, metabolic, molecular, and ecological characteristics. In addition to analysis of their anatomical and ecological features, DNA barcoding was performed for molecular characterization through internal transcribed spacer (ITS) sequencing and start codon targeted (SCoT) markers. Furthermore, metabolic profiling of the studied species was conducted based on gas chromatography–mass spectrometry (GC-MS). The observed anatomical features of the adaxial and abaxial epidermal layers, type of mesophyll, crystals, number of palisade and spongy layers, and the vascular system showed variations between the studied species. Beyond this, the anatomy of the leaves showed an isobilateral structure in the studied species, without distinct differences. Species were molecularly identified in terms of ITS sequences and SCoT markers. The ITS sequences were deposited in GenBank with accession numbers ON149839.1, OP597546.1, and ON521125.1 for L. europaeum L., L. shawii, and L. schweinfurthii var. aschersonii, respectively. The sequences showed variations in GC content between the studied species; this was 63.6% in L. europaeum, 61.53% in L. shawii, and 63.55% in L. schweinfurthii var. aschersonii. A total of 62 amplified fragments, including 44 polymorphic fragments with a ratio of 70.97%, were obtained in the SCoT analysis, as well as unique amplicons in L. europaeum L., shawii, and L. schweinfurthii var. aschersonii of 5, 11, and 4 fragments, respectively. Through GC-MS profiling, 38 compounds were identified with clear fluctuations in the extracts of each species. Of these, 23 were distinguishing chemicals that could help in chemical identification of the extracts of the studied species. The present study succeeds in identifying alternative clear and diverse characteristics that can be used to distinguish between L. europaeum, L. shawii, and L. schweinfurthii var. aschersonii.

show abstract

The genus Lycium as food and medicine: A botanical, ethnobotanical and historical review

Yao

Heinrich

Weckerle

2018

Journal of Ethnopharmacology

157

113

View full text Add to dashboard Cite

show abstract

Anti-Fatigue and Anti-Hypoxic Effects of Lycium barbarum Polysaccharides

Cited by 4 publications

References 9 publications

Can Goji Berry Extract Attenuate Pancreatic Structural Changes Induced by Patulin Toxin in Male Albino Rats?

Can Goji Berry Extract Attenuate Pancreatic Structural Changes Induced by Patulin Toxin in Male Albino Rats?

Distinguishing features of Lycium L. species (family Solanaceae) distributed in Egypt based on their anatomical, metabolic, molecular, and ecological characteristics

The genus Lycium as food and medicine: A botanical, ethnobotanical and historical review

Contact Info

Product

Resources

About