Anti Epileptic Activity of Poly Herbal Extract from Indian Medicinal Plants

Balamurugan, G.; Dharan, Murali; Rajan, S. Y.

doi:10.3329/jsr.v1i1.1057

Cited by 14 publications

(13 citation statements)

References 6 publications

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“…This increases the contact and reduces the incidence of fatalities. The observed duration of various phases of epilepsy was tabulated (Balamurgan et al, 2009). …”

Section: Pentobarbital Sleeping Timementioning

confidence: 99%

Sedative, antiepileptic and antipsychotic effects of Viscum album L. (Loranthaceae) in mice and rats

Gupta

Kazmi

Afzal

et al. 2012

Journal of Ethnopharmacology

134

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“…This increases the contact and reduces the incidence of fatalities. The observed duration of various phases of epilepsy was tabulated (Balamurgan et al, 2009). …”

Section: Pentobarbital Sleeping Timementioning

confidence: 99%

Sedative, antiepileptic and antipsychotic effects of Viscum album L. (Loranthaceae) in mice and rats

Gupta

Kazmi

Afzal

et al. 2012

Journal of Ethnopharmacology

134

View full text Add to dashboard Cite

“…A low concentration of dopamine in cerebellum also has an inhibitory effect on glutamate. Inhibition of prostaglandin synthesis is reported to increase the brain levels of dopamine and noradrenaline, which also causes an inhibition of seizure activity (Balamurugan et al, 2009).…”

Section: Discussionmentioning

confidence: 99%

“…Withania somnifera: A poly herbal extract comprising of Withania somnifera Dunal, a medicinal plant used in many neuro protective Ayurvedic medicines along with five other medicinal plants were evaluated for its protective effect against seizures induced by MES method. The uses of these medicinal plants are in the treatment of epilepsy (Balamurugan et al, 2009).…”

Section: Prevalence Of Epilepsymentioning

confidence: 99%

Anticonvulsant potential of some medicinal plants and their beneficial properties

Asif¹

2013

TANG [HUMANITAS MEDICINE]

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Epilepsy has now become the most serious brain disorder. A number of synthetic antiepileptic drugs are available in practice, however their effectiveness does not grip true with the entire population suffering from epilepsy. Traditional systems of medicine are popular in developing countries and most of the population relies on traditional medicines for their primary health care need. Medicinal plants to be an important source of traditional medicines. Various plants are used for the treatment of epilepsy in traditional system of medicines and various plants are yet to be scientifically investigated. Phytoconstituents have been the basis of treatment of human diseases including epilepsy. Herbal products are extensively used for the treatment of many diseases worldwide and where allopathic fails or has severe side effects. Psycho neural drugs are also have very serious side effects like physical dependence, tolerance, deterioration of cognitive function and effect on respiratory, digestive and immune system. So the treatments through herbal medicines are widely used across the world due to their wide applicability and therapeutic efficacy with least side effects, which in turn has accelerated the research regarding natural therapy. In this review we have summarized some herbal antiepileptics.

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“…The fluorophore was developed by heating to 100°C for 10 min. After the samples reached equilibrium with the ambient temperature, readings were taken at wavelengths of 360-470 nm in the spectrofluorometer (Balamurugan et al, 2009).…”

Section: Estimating Of Serotoninmentioning

confidence: 99%

Antidepressant activity of Citrus limetta leaves in mice using battery of behavior models modulating via serotonergic systems

Kaur¹,

Bhatia²,

Nain³

2019

Bangladesh J Pharmacol

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The methanolic extract of Citrus limetta leaves was estimated in the present study for antidepressant activity. This activity was evaluated by using the rat behavioral model i.e. forced swimming and tail suspension model for 14 days, with estimation of neurotransmitters in animals brain. The sedative effect was evaluated by actophotometer. The extract (200 mg/kg) administered orally showed significant (p<0.05) decrease in immobility time against the standard drug fluoxetine (20 mg/kg, i.p), and imipramine (15 mg/kg, i.p.) respectively but no significant reduction was found in the locomotor activity against diazepam (2 mg/kg, i.p.). In depression, the brain reflected low monoamines level like release of norepinephrine, dopamine and serotonin but 14 days after successive administration of the extract, their levels were significantly increased. In conclusion, C. limetta showed significant antidepressant activity. Video Clip of Methodology: Forced swimming test: 6 min 17 sec: Full Screen Alternate

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Anti Epileptic Activity of Poly Herbal Extract from Indian Medicinal Plants

Cited by 14 publications

References 6 publications

Sedative, antiepileptic and antipsychotic effects of Viscum album L. (Loranthaceae) in mice and rats

Sedative, antiepileptic and antipsychotic effects of Viscum album L. (Loranthaceae) in mice and rats

Anticonvulsant potential of some medicinal plants and their beneficial properties

Antidepressant activity of Citrus limetta leaves in mice using battery of behavior models modulating via serotonergic systems

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