Anti-diabetic drugs utilization pattern and its cost in managing Type 2 Diabetes patients in hospitals in Selangor, Malaysia

Yunus, Sharifah Zawani Syed Ahmad; Bakar, Nurul Salwana binti Abu; Musa, Nurul Syarbani Eliana; Sapian, Roslinda Abu; Azahar, Amnah; Zainuddin, Nur Azmiah

doi:10.1016/j.imu.2018.09.002

Cited by 3 publications

(2 citation statements)

References 8 publications

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“…Similar to other studies, we found that the most commonly prescribed antihypertensive were calcium channel blockers and thiazides [29,31]. For the antidiabetic medication, the most common drugs used by the study population were biguanides (metformin) followed by sulphonylureas (glibenclamide) which is similar to those reported by Yunus and colleagues (2018) in a study conducted in Malaysia [32].…”

Section: Discussionsupporting

confidence: 88%

Care-Seeking Dynamics among Patients with Diabetes Mellitus and Hypertension in Selected Rural Settings in Kenya

Karinja

Pillai

Schlienger

et al. 2019

IJERPH

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Diabetes mellitus and hypertension are two common non-communicable diseases (NCDs) that often coexist in patients. However, health-seeking behaviour in patients with diabetes mellitus or hypertension has not been extensively studied especially in low- and middle-income countries. This study aimed to examine care-seeking dynamics among participants diagnosed with diabetes and/or hypertension across nine counties in rural Kenya. We conducted a cross-sectional study among adults diagnosed with diabetes and/or hypertension through face-to-face interviews. Of the 1100 participants, 69.9% had hypertension, 15.5% diabetes while 14.7% had both. The mean age of the respondents was 64 years. The majority of the respondents (86%) were on allopathic treatment. Hospital admission, having a good self-rated health status and having social support for illness, were positively associated with appropriate health-seeking behaviour while use of alcohol and pharmacy or chemist as source of treatment were negatively associated with appropriate health-seeking behaviour. Our study found a high prevalence of appropriate health-seeking behaviour among respondents with the majority obtaining care from government facilities. The results are evidence that improving public health care services can promote appropriate health-seeking behaviour for non-communicable diseases and thus improve health outcomes.

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Section: Discussionsupporting

confidence: 88%

Care-Seeking Dynamics among Patients with Diabetes Mellitus and Hypertension in Selected Rural Settings in Kenya

Karinja

Pillai

Schlienger

et al. 2019

IJERPH

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“…Overall, monotherapy predominated over multiple-therapy. Results from a study done by Syed [28] is in line with these findings where monotherapy is used as a first line treatment, followed by second line with combinations of 2 or more OHAs. If glycemic control is not achieved by monotherapy, only then a combination therapy will be initiated based on CPG of T2 DM by Kamarudin [16] .…”

Section: Drug Utilization Based On Pharmacological Classificationsupporting

confidence: 62%

Prescribing Trend and Drug Cost Analysis of Oral Hypoglycemic Agents Using Drug Utilisation Review

Chanthran¹,

Ming

Tan³

et al. 2020

MJPHM

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Drug utilization of oral hypoglycemic agents (OHAs) in a private healthcare setting is useful to examine the prescribing pattern of OHAs, especially the newer fixed dose combination (FDC) products. This study was aimed to evaluate the prescribing pattern of OHAs indicated for Type 2 diabetes mellitus (T2DM), to determine the costs of OHAs prescribed and total cost per prescription in the treatment of T2DM in an outpatient department of a private hospital located in central Malaysia. Retrospective review of electronic medical record (EMR) study design was adopted. Patient’s demographic characteristics, medications prescribed, prescribers’ details and cost per prescription were documented. Defined daily dose (DDD) of OHAs and drug cost were calculated. Research ethics protocol was approved and no personal data was collected. Out of the 396 EMR screened, 135 fulfilled the inclusion criteria and subsequently were analysed. In term of demography, mean age of the sample was 51 years old with 59% were male and ethnicity composition of 71% Malay and 19% Chinese. Metformin and “metformin+dipeptidyl peptidase-4 inhibitor” (DPP-4i) were the most commonly prescribed single-drug and FDC OHA, respectively. Average cost of OHAs and total cost per prescription was less than USD 68 and USD 185, respectively. Meanwhile, FDC covered 28.91% of incidences of prescriptions, but 44.6% of cost and SGTL-2i covered 9% incidences of prescriptions and 16.29% of cost. Prescribing pattern of OHA was appropriate based on patient’s T2DM diagnosis, however, dosage given were not in accordance with WHO DDD.

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Main drivers of diabetes pharmaceuticals expenditures: evidence from OECD countries and Iran

Akbarpour

Zarei

Varahrami

et al. 2022

J Diabetes Metab Disord

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Anti-diabetic drugs utilization pattern and its cost in managing Type 2 Diabetes patients in hospitals in Selangor, Malaysia

Cited by 3 publications

References 8 publications

Care-Seeking Dynamics among Patients with Diabetes Mellitus and Hypertension in Selected Rural Settings in Kenya

Care-Seeking Dynamics among Patients with Diabetes Mellitus and Hypertension in Selected Rural Settings in Kenya

Prescribing Trend and Drug Cost Analysis of Oral Hypoglycemic Agents Using Drug Utilisation Review

Main drivers of diabetes pharmaceuticals expenditures: evidence from OECD countries and Iran

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