Anti-demineralization characteristics of surface pre-reacted glass-ionomer (S-PRG) filler-containing varnishes

Shiiya, Toru; Kataoka, Aiko; Tomiyama, Kiyoshi; Fujino, Fukue; Mukai, Yukinori

doi:10.4012/dmj.2019-396

Cited by 5 publications

(4 citation statements)

References 32 publications

(35 reference statements)

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“…The OBR was used, as mentioned in previous studies for studying the effects of biofilm [34]. Likewise, the primary biofilm was formed in the OBR in the present study, simulating clinical dental plaque, unlike the artificial demineralization solution used previously for the evaluation of S-PRG filler containing DVs [35]. Hence, the results acquired after the biofilm challenge on the DV-treated specimens are more reliable.…”

Section: Discussionmentioning

confidence: 89%

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Optimal Surface Pre-Reacted Glass Filler Ratio in a Dental Varnish Effective for Inhibition of Biofilm-Induced Root Dentin Demineralization

et al. 2022

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A unique type of dental varnish (DV) containing surface pre-reacted glass (S-PRG) fillers of different concentrations was evaluated to determine the unpresented optimal ratio for inhibiting root dentin bio-demineralization. S-PRG DVs (10% to 40%)—10%-S, 20%-S, 30%-S, and 40%-S—were applied to bovine root dentin blocks and compared with controls—0%-f (no S-PRG) and 5%-NaF (5%-NaF). The Streptococcus mutans biofilm challenge was executed inside and outside an oral biofilm reactor for 7 days. The specimens were examined using a confocal laser scanning microscope and swept-source optical coherence tomography. Furthermore, they were observed using a scanning electron microscope and analyzed using energy-dispersive X-ray spectroscopy. The roughness (SzJIS) due to leaching of DV materials and demineralization depth were significantly less in the S-PRG groups than the control groups (p < 0.05). Complete or partially plugged dentinal tubules (DTs) were observed in 20%-S, 30%-S, and 40%-S, while wide-open DTs were observed more in controls. Cylindrical tags were present in groups containing more than 20% S-PRG. F, Na, Al, and Sr were detected in a higher percentile ratio in the 20%-S, 30%-S, and 40%-S groups compared to 0%-f and 10%-S. Nonetheless, it is suggested that incorporating 20% to 30% S-PRG fillers in DVs would be effective enough as an anti-demineralization coating, together with supplementing minerals; further evaluation is required to validate these findings.

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Section: Discussionmentioning

confidence: 89%

“…The root surface is more susceptible to acid demineralization compared to enamel [35,36]. Products with higher fluoride (F) concentrations have been suggested for the protection of the root surface [37,38].…”

Section: Discussionmentioning

confidence: 99%

Optimal Surface Pre-Reacted Glass Filler Ratio in a Dental Varnish Effective for Inhibition of Biofilm-Induced Root Dentin Demineralization

et al. 2022

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“…Fluoride deposition on the tooth is a well-known effective method for caries control [Ogawa et al, 2019]. Accordingly, a lot of dental products and different forms of applications have been developed with the aim to reduce tooth demineralization and to improve tooth remineralization [Iijima et al, 2019], such as toothpaste, mouth rinse, fluoride-releasing adhesives, varnishes, and sealants [Featherstone, 2009;Iijima et al, 2019;Spinola et al, 2020;Shiiya et al, 2021].…”

Section: Introductionmentioning

confidence: 99%

“…Surface pre-reacted glass-ionomer (S-PRG) filler, the active ingredient of commercially available GIOMER products (Shofu ® , Kyoto, Japan) has been included into various dental materials [Rossoni et al, 2019], such as bonding systems, varnishes, cements, composite resins, denture base resin, resin barrier coats, fissure sealants, toothpastes, and even on the bristles of toothbrushes [Han et al, 2002;Itota et al, 2004;Fujimoto et al, 2010;Ito et al, 2011;Asano et al, 2014;Kaga et al, 2014;Suzuki et al, 2014;Yoneda et al, 2015;Amaechi et al, 2017Amaechi et al, , 2018Nomura et al, 2018;Spinola et al, 2020;Matayoshi et al, 2021;Shiiya et al, 2021].…”

Section: Introductionmentioning

confidence: 99%

Effect of a Toothpaste Containing Surface Pre-Reacted Glass-Ionomer Filler on the Remineralization of Artificial Carious Enamel Lesions in situ

Vertuan¹,

Silva²,

Ferreira³

et al. 2022

Caries Res

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This study evaluated the remineralizing effect of a toothpaste containing surface pre-reacted glass-ionomer (S-PRG) filler on demineralized enamel in situ. For this, 180 bovine enamel samples were demineralized by using a microcosm biofilm model for 3 days. Thereafter, the samples were randomly signed to 15 healthy volunteers and to 3 cross-over in situ phases corresponding to the following treatments: 1) toothpaste containing 1500 ppm F as NaMFP (positive control, Colgate® Cavity Protection), 2) toothpaste containing 5% S-PRG filler (Shofu®), and 3) placebo toothpaste (negative control prepared by Shofu®). Four demineralized enamel blocks were fixed into each palatal appliance per phase. The volunteers wore the appliances for 5 days and were trained to brush their teeth 2 times for 2 minute a day, while one drop of the toothpaste’s slurry (1:3) was dripped on each sample for the same period. The surface hardness and TMR analyses were done and analyzed by ANOVA/Tukey and t test (p<0.05). S-PRG filler and Colgate® toothpastes were equally able to improve 2-2.5x enamel remineralization by the analysis of % surface hardness recovery. However, S-PRG toothpaste was the only one able to significantly improve ΔΔZ (the integrated mineral loss recovery: 1489 ± 503 %vol.μm) compared to placebo (1050 ± 467 %vol.μm), while Colgate® did not differ from placebo. No differences were seen between the groups with respect to ΔLD. S-PRG filler and Colgate® toothpastes shows similar potential to remineralize the lesion surface. However, S-PRG toothpaste is better to recovery mineral loss at the subsurface area.

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Dentin anti-demineralization potential of surface reaction-type pre-reacted glass-ionomer filler containing self-adhesive resin cement

et al. 2021

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Anti-demineralization characteristics of surface pre-reacted glass-ionomer (S-PRG) filler-containing varnishes

Cited by 5 publications

References 32 publications

Optimal Surface Pre-Reacted Glass Filler Ratio in a Dental Varnish Effective for Inhibition of Biofilm-Induced Root Dentin Demineralization

Optimal Surface Pre-Reacted Glass Filler Ratio in a Dental Varnish Effective for Inhibition of Biofilm-Induced Root Dentin Demineralization

Effect of a Toothpaste Containing Surface Pre-Reacted Glass-Ionomer Filler on the Remineralization of Artificial Carious Enamel Lesions in situ

Dentin anti-demineralization potential of surface reaction-type pre-reacted glass-ionomer filler containing self-adhesive resin cement

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