Anti-candida, anti-coagulant and thrombolytic activities of biosynthesized silver nanoparticles using cell-free extract of Bacillus safensis LAU 13

Lateef, Agbaje; Ojo, Sunday A.; Oladejo, Suliat M.

doi:10.1016/j.procbio.2016.06.027

Cited by 79 publications

(47 citation statements)

References 41 publications

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“…Consequently, there arose a demand for green nanotechnology that comprises clean, safe, and environmentally friendly systems of nanoparticles fabrication. 2 The biological technique, which is a key component of the green nanotechnology has expanded in the last decade to biosynthesize metallic nanoparticles owing to abundance of a wide-range of biological resources such as bacteria, [3][4][5][6][7] fungi, 8 plants' extracts, [9][10][11][12][13][14] enzymes, [15][16][17][18][19][20][21] as well as metabolites of arthropods. [22][23][24][25][26][27][28][29] There are outstanding reviews on the use of pigments, agrowastes, enzymes, arthropods, and their metabolites for the ecofriendly and benign synthesis of nanoparticles.…”

Section: Introductionmentioning

confidence: 99%

Silver‐gold alloy nanoparticles biofabricated by fungal xylanases exhibited potent biomedical and catalytic activities

Elegbede

Lateef

Azeez

et al. 2019

Biotechnology Progress

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The search for biocompatible nanoparticles with vast applicability has impacted on exploration of various biomaterials for the synthesis of mono and bimetallic nanoparticles. Xylanase is widely regarded as an industrially important enzyme but its potentials in nanotechnological applications are yet to be fully explored. The current study investigates the exploit of xylanases of Aspergillus niger L3 (NE) and Trichoderma longibrachiatum L2 (TE) produced through valorization of corn‐cob, to synthesize silver‐gold alloy nanoparticles (Ag‐AuNPs). Characterization of the Ag‐AuNPs involved UV–vis spectroscopy, Fourier transform infrared spectroscopy (FTIR), and field emission scanning electron microscopy and transmission electron microscopy, while their prospective use as antimicrobial, antioxidant, catalytic, anticoagulant, and thrombolytic agents were studied. The biosynthesized Ag‐AuNPs were ruby red and light purple with surface plasmon resonance at 520 and 534 nm for NEAg‐AuNPs and TEAg‐AuNPs, respectively; while FTIR showed that protein molecules capped and stabilized the nanoparticles. The Ag‐AuNPs were anisotropic with spherical, oval, and irregular shapes having sizes ranging from 6.98 to 52.51 nm. The nanoparticles appreciably inhibited the growth of tested clinical bacteria (23.40–90.70%) and fungi (70.10–89.05%), and also scavenged 2,2‐diphenyl‐1‐picrylhydrazyl (48.51–53.79%) and hydrogen peroxide (80.5–95.50%). Furthermore, the Ag‐AuNPs degraded malachite green (91.39%) and methylene blue (47.10%). Moreover, the Ag‐AuNPs displayed outstanding anticoagulant and thrombolytic activities using human blood. This study further emphasizes the significance of xylanases in nanobiotechnology as it has established the potential of xylanases to synthesize Ag‐AuNPs, which is being reported for the first time.

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Section: Introductionmentioning

confidence: 99%

Silver‐gold alloy nanoparticles biofabricated by fungal xylanases exhibited potent biomedical and catalytic activities

Elegbede

Lateef

Azeez

et al. 2019

Biotechnology Progress

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“…Furthermore, the AgNPs was active against deterioration microorganisms in paints; with a total inhibition of microbial growth. Likewise, in anti-candidal activity test, results obtained showed inhibition of C. albicans by the synthesized AgNPs with MIC recorded at 40 µg/mL (Lateef et al, 2016e). Lateef et al (2015e) utilized extracts of seed (SE) and seed shell (SS) of Cola nitida to produce AgNPs with SPR of 457.5 and 454.5 nm obtained respectively.…”

Section: Studies On Applications Of Nanoparticlesmentioning

confidence: 98%

“…Silver nanoparticles biofabricated through B. safensis extract(Lateef et al, 2016e) was reported to have inhibited clotting of human blood, while it also displayed thrombolysis by dissolving pre-formed blood clot. Similarly, S. dulcificum mediated AgNPs(Lateef et al, 2016g) as mentioned previously have displayed incredible blood anticoagulant activities, where clotting of blood samples was well prevented.…”

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confidence: 99%

Green Nanotechnology in Nigeria: The Research Landscape, Challenges and Prospects

Elegbede¹,

Lateef

2019

Annals of Science and Technology

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In this treatise, we examined the activities of researchers of Nigeria descent in the frontier areas of nanoscience and nanotechnology, with a focus on green nanotechnology. The exploration of literature published by scholars were reviewed and compartmentalized on the basis of applications of the nanomaterials. It can be concluded that the level of activities in this area is expanding owing to the emergence of more published works since the beginning of 2010. However, in comparison with research outputs from other developing African countries such as South Africa and Egypt, activities in green nanotechnology are still at low ebb in Nigeria. Issues that are contributory to the slow pace were identified and appropriate solutions in terms of improved funding of education, enactment of national policy on nanotechnology, curriculum development, international cooperation as well as human resource development among others were discussed.

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“…The intense research interest is due to diverse applications in different fields, for example, biomedical (Chaloupka et al, 2010), drug delivery (Prow et al, 2011), water treatment (Dankovich and Gray, 2011), agriculture (Nair et al, 2010) and sensors (Pandey et al, 2012;Pandey et al, 2013a, b;Tran et al, 2013). Furthermore, the larvicidal, antibacterial, antifungal anticoagulant and thrombolytic activities of silver nanoparticles have been extensively investigated (Lateef et al, 2015(Lateef et al, , 2016aLateef et al, 2016c). Consequently, a number of studies are geared towards development of suitable protocols for the rational synthesis of metal and/or bimetallic nanoparticles in an eco-friendly approach.…”

Section: Introductionmentioning

confidence: 99%

Green synthesis of silver monometallic and copper-silver bimetallic nanoparticles using Kigelia africana fruit extract and evaluation of their antimicrobial activities

Ashishie¹,

Anyama²,

Ayi³

et al. 2018

Int. J. Phys. Sci.

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Aqueous extract of Kigelia africana fruits have been utilized in the syntheses of silver nanoparticles (AgNPs) and copper-silver bimetallic nanoparticles (Ag-CuNPs). The synthesized nanoparticles have been characterized using UV-vis, Fourier-transform infrared spectroscopy (FTIR), scanning electron microscopy/energy dispersive X-ray analysis (SEM/EDX), x-ray diffration (XRD) and transmission electron microscopy (TEM). The antimicrobial activities have been evaluated against both Grams-negative and Grams-positive strains of bacteria and fungus. The UV-vis and FTIR techniques revealed the formation of nanoparticles and the active components were adsorbed on the surface of the particles thereby stabilizing the nanoparticles. The SEM reveals uniform microspheres of AgNPs and anisotropic particles for AgCuNPs. TEM shows a particle size of 10 nm. The nanoparticles inhibit the growth of both Grams-negative and Grams-positive bacteria. The present nanoparticles synthesized from aqueous extract of K. africana fruits inhibits Klebsiella pneumoniae more than any of the antibiotics tested in this study. It competes very well with augmentin against Pseudomonas aeruginosa and with meropenem against Candida albicans with inhibition zones of 23 and 25 mm, respectively. The bimetallic nanoparticles have demonstrated effectiveness against Staphylococcus aureus, with maximum inhibition zone of 27 mm.

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Anti-candida, anti-coagulant and thrombolytic activities of biosynthesized silver nanoparticles using cell-free extract of Bacillus safensis LAU 13

Cited by 79 publications

References 41 publications

Silver‐gold alloy nanoparticles biofabricated by fungal xylanases exhibited potent biomedical and catalytic activities

Silver‐gold alloy nanoparticles biofabricated by fungal xylanases exhibited potent biomedical and catalytic activities

Green Nanotechnology in Nigeria: The Research Landscape, Challenges and Prospects

Green synthesis of silver monometallic and copper-silver bimetallic nanoparticles using Kigelia africana fruit extract and evaluation of their antimicrobial activities

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