Anti-arthritic activity of various extracts of<i>Sida rhombifolia</i>aerial parts

Gupta, Sourabh; Nirmal, S. A.; Patil, Ravindra; Asane, Govind S.

doi:10.1080/14786410802242778

Cited by 28 publications

(8 citation statements)

References 8 publications

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“…In another report, it has been discussed that methanolic extract of its aerial part showed anti-inflammatory activity in animal model study [22]. Ethanol and aqueous extracts of aerial parts of the plant were also reported to be useful in the treatment of arthritis [23]. A recent report from experimental result of Ranjan et al [24] also showed significant anti diarrheal activity of methanolic extract of Sida rhombifolia.…”

Section: Introductionmentioning

confidence: 85%

Evaluation of Antibacterial Activities of Compounds Isolated From Sida rhombifolia Linn. (Malvaceae)

Woldeyes¹

2014

Nat Prod Chem Res 2014

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The main objective of this study was to isolate compounds from roots of Sida rhombifolia and subsequently evaluate their antibacterial activities. Crude gradient extracts were obtained from three solvents (petroleum ether, chloroform and methanol) with increasing solvent polarity using cold maceration technique. The in vitro antibacterial activity evaluation of gradient extracts and isolated compounds was done on four different pathogenic bacterial strains (Staphylococcus aureus, Escherichia coli, Pseudomonas aeruginosa and Salmonella typhimurium) using agar disc diffusion technique. The results showed that antibacterial activities were comparable to each other. But their activities were relatively weaker as compared to that of the reference compound (ciprofloxacin). Among the three crude extracts, the chloroform extract was subjected to column chromatographic separation that led to isolation of SRL-1, SRL-2 and SRL-3. The chemical structures of the compounds were found to be n-hexacos-11-enoic acid, stigmasterol and β-sitosterol, respectively, based on physical properties and spectroscopic (IR and NMR) data as well as literature reports. The observed antibacterial activities of the crude extracts and the isolated compounds could justify the traditional use of the plant for the treatment of different bacterial infections. Thus, further test is recommended on large number of bacterial strains to decide the potentials of the compounds as candidates in development of antibacterial drugs.

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Section: Introductionmentioning

confidence: 85%

Evaluation of Antibacterial Activities of Compounds Isolated From Sida rhombifolia Linn. (Malvaceae)

Woldeyes¹

2014

Nat Prod Chem Res 2014

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“…SR is a small erect under shrub having rough branches with stellate hairs commonly found in dry countries such as India and Ceylon [ 218 ]. Traditionally, the plant is used as nutritive, tonic and for the treatment of gonorrhea, piles, rheumatism, as diuretic, and aphrodisiac [ 51 ].…”

Section: Resultsmentioning

confidence: 99%

“…The aqueous and ethanol extract of aerial parts of the SR at doses 30 and 100 mg/kg reduced the paw edema induced by CFA method. Thus, it is concluded that the plant possess a potent anti-arthritic activity [ 218 ].…”

Section: Resultsmentioning

confidence: 99%

Medicinal plants with potential anti-arthritic activity:

Choudhary

Kumar

Malhotra

et al. 2015

J Intercult Ethnopharmacol

132

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Ethno Pharmacological Relevance: Traditional medicinal plants are practiced worldwide for treatment of arthritis especially in developing countries where resources are meager. This review presents the plants profiles inhabiting throughout the world regarding their traditional usage by various tribes/ethnic groups for treatment of arthritis.Materials and Methods:Bibliographic investigation was carried out by analyzing classical text books and peer reviewed papers, consulting worldwide accepted scientific databases from the last six decades. Plants/their parts/extracts/polyherbal formulations, toxicity studies for arthritis have been included in the review article. The profiles presented also include information about the scientific name, family, dose, methodology along with mechanism of action and toxicity profile. Research status of 20 potential plant species has been discussed. Further, geographical distribution of research, plants distribution according to families has been given in graphical form.Results:485 plant species belonging to 100 families, traditionally used in arthritis are used. Among 100 plant families, malvaceae constitute 16, leguminasae 7, fabaceae 13, euphorbiaceae 7, compositae 20, araceae 7, solanaceae 12, liliaceae 9, apocynaceae, lauraceae, and rubiaceae 10, and remaining in lesser proportion. It was observed in our study that majority of researches are carried mainly in developing countries like India, China, Korea and Nigeria.Conclusion:This review clearly indicates that list of medicinal plants presented in this review might be useful to researchers as well as practioners. This review can be useful for preliminary screening of potential anti-arthritis plants. Further toxicity profile given in the review can be useful for the researchers for finding the safe dose.

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“…The World Health Organization (WHO) presently inspires, recommends and encourages traditional remedies in health care plans as they're simply obtainable at low value, relatively harmless and traditionally common [9]. The plant growths leads to the production various chemical compounds are called phytochemicals and refer as "secondary metabolites" that consist, flavonoids, alkaloids, coumarins, tannins, phenols, phlobatannins, anthraquinones, terpenoids, cardiac glycosides, steroid and phytosteroid [10]. It is known that the phytochemical compounds identified have medicinal significance.…”

Section: Quantitative and Qualitative Identification Ofmentioning

confidence: 99%

Quantitative and Qualitative Identification of Phytochemical Constituents of Sida Rhombifolia Leaves Extract

2019

ijrte

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Anti-inflammatory, analgesic, antimicrobial, anti-arthritic, antibacterial, antispasmodic, hypoglycaemic and hepatoprotective characteristics of Sida rhombifolia are included in the Malvaceae family. Most of the plant belongs to the Malvaceae family, as they comprise a number of phytochemicals and biological compounds, are potential sources of different medications. This is study on Sida rhombifolia leaf extract's tophytochemical constituen ts. Phytochemical screening results in herbal stan-dardizat ion and preparation and may relate the components to thei r medicinal / pharmacological uses. The qualitative phytochemical analysis has shown that the extract is positive for saponins, flavonoids, alkaloids, phenols and same extract is negative for carbohydrate, tannins, glycosides, cardiac glycosides, terpenoids, coumarins, steroid& phytosteroids, phlobutanins, anthraquinones. Quantitative analysis of phytochemicals includes the estimation of flavonoid, tannin and total content of phenol. The result suggest that the Sida rhombifolia leaves extract consist plenty of phytochemicals beneficial in alternative medical and pharmaceutical industries.

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Anti-arthritic activity of various extracts ofSida rhombifoliaaerial parts

Cited by 28 publications

References 8 publications

Evaluation of Antibacterial Activities of Compounds Isolated From Sida rhombifolia Linn. (Malvaceae)

Evaluation of Antibacterial Activities of Compounds Isolated From Sida rhombifolia Linn. (Malvaceae)

Medicinal plants with potential anti-arthritic activity:

Quantitative and Qualitative Identification of Phytochemical Constituents of Sida Rhombifolia Leaves Extract

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