Anti-Acne Activity From Biocellulose Mask Formula Containing (Aloe Vera (L.) Burm.F) Essence Combined With Vitamin E

Fitri, Raissa; Reveny, Julia; Harahap, Urip; Dharmawan, Hariyadi; Nasri, Nasri

doi:10.32734/idjpcr.v4i1.5382

Cited by 8 publications

(11 citation statements)

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“…The pH of the preparation greatly affects whether the formulation that is formulated is able to irritate the user or not. The results of the formulations showed that the pH of each formula was in the range of 4-5 [34]. Based on SNI No.…”

Section: Homogenitymentioning

confidence: 99%

Phytochemical Screening and Formulation of Hand Sanitizer Gel Preparations from Temu Hitam Rhizome Extract (Curcuma aeruginosa Roxb)

Sari

Harnis

Harahap

2022

International Journal of Science, Technology & Management

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Temu Hitam (Curcuma aeruginosa Roxb) is one of the most widely grown plants in Indonesia at an altitude of 400–750 m asl and contains many secondary metabolites, including flavonoids, alkaloids, saponins, tannins, and curcuminoids, which in the test had antibacterial activity and growth inhibitors. worm larvae in the gastrointestinal tract and the effect of increasing the body's immunity The purpose of this study was to identify the content of secondary metabolites contained in the rhizome of black turmeric, which would then be formulated into gel hand sanitizer preparations. Secondary metabolite testing was conducted on alkaloids, flavonoids, saponins, tannins, steroids/triterpenoids, and glycosides. Three different hand sanitizer gel formulations were created using different extract concentrations, 5%, 10%, and 15%. Evaluation tests were then run on the preparations, including stability, organoleptic, homogeneity, pH, and dispersion tests. Alkaloids, flavonoids, tannins, saponins, and steroids were found in the temu hitam rhizome, according to the results of secondary metabolite testing. The dosage form was semi-solid, had a light brown to blackish brown hue, a distinct spice scent, was homogeneously prepared, and had a pH of 7.0, according to the examination of the formulation results 4,1 ± 0,17; 4,4 ± 0,19; 4,9 ± 0,08; 4,9 ± 0,09, viscosity 2378 ± 209,9; 3340 ± 220,7; 4509 ± 285,6; 4881 ± 276,7; and spreadability test 5; 6,2; 5,4; 4,9 cm . The conclusion of this study is that the results of the phytochemical screening of simplicia and the ethanolic extract of the Temu Hitam rhizome showed positive results, containing secondary metabolites of alkaloids, flavonoids, tannins, saponins, glycosides, and steroids/triterpenoids that can be formulated into hand sanitizer gel preparations that meet the requirements for preparation evaluation.

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Section: Homogenitymentioning

confidence: 99%

Phytochemical Screening and Formulation of Hand Sanitizer Gel Preparations from Temu Hitam Rhizome Extract (Curcuma aeruginosa Roxb)

Sari

Harnis

Harahap

2022

International Journal of Science, Technology & Management

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“…Incubated at 36 oC for 24 hours, the treatment was repeated three times. Then the zone of inhibition was measured with a caliper (mm) [14], [15].…”

Section: Determination Of Minimum Inhibitory Concentration (Mic)mentioning

confidence: 99%

Antibacterial Potential Of Ethanol Extract Of Tamarind Seed Bark (Tamarindus indica L.) And Formulation Of Anti-Acne Nanogel

Amalyuri

Reveny

Dalimunthe

2022

International Journal of Science, Technology & Management

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Acne is a skin disease that affects a large number of sufferers. Acne occurs due to active oil glands under the skin. This activity is stimulated by androgen hormones. The active compound content of proanthocyanidin is the main compound in the ethanolic extract of tamarind seed bark, which can inhibit the growth of acne-causing bacteria, namely Propionibacterium acnes and Staphylococcus epidermidis. The purpose of this study was to formulate a nanogel from tamarind seed bark extract and test the antibacterial potential of an ethanol extract of tamarind seeds against acne-causing bacteria. The antibacterial potency test consisted of variations in concentration and was 0.5, 1, 5, 25, 50, 75, 100, 125, 150, and 300 (in mg/mL). The concentration of the formulated nanogel preparations was 2.5%, 5%, and 7.5%. The MIC results showed that the minimum inhibitory concentration (MIC) was at a concentration of 1 mg/mL with a zone of inhibition of 6.50 ± 0.44 mm (Propionibacterium acnes) and 6.40 ± 0.10 mm (Staphylococcus epidermidis). The minimum bactericidal concentration (MBC) was at a concentration of 25 mg/mL with a percentage reduction of 98.18% (Propionibacterium acnes) and 98.06% (Staphylococcus epidermidis). The results of the nanogel formulations showed that the particle sizes were 49.88 ± 0.11 nm (Formula I), 51.92 ± 0.09 nm (Formula II), and 59.13 ± 0.10 nm (Formula III). Conclusion The ethanolic extract of tamarind seed bark has effectiveness in inhibiting the growth of acne-causing bacteria and can be formulated as an anti-acne nanogel.

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“…One sample of revitalized bacteria was suspended in a test tube containing 10 mL of MHB medium, vortexed, and turbidity was adjusted using 0.5 McFarland standards 7,13 .…”

Section: Preparation Of Bacterial Suspensionmentioning

confidence: 99%

Antibacterial Activity Ethanolic Extract of Ocimum basilicum L. Leaves in Inhibiting the Growth of Escherichia coli and Pseudomonas aeruginosa

Lubis

Syahputra

Astyka

2022

Nusantara Scientific Medical Research Journal

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Infectious disease is the biggest problem in the world. The problem with this infection is related to antibiotic resistance if its use is not consistent. Utilization of kemangi leaves, which are always used as fresh vegetables, has potential as an antibacterial in inhibiting the growth of Escherichia coli and Pseudomonas aeruginosa bacteria. This study aims to analyze the inhibition of an ethanol extract of kemangi leaves against Escherichia coli and Pseudomonas aeruginosa. The Kirby-Bauer method with the disc diffusion method was used to determine the minimum inhibitory diameter and to calculate the activity index value. The test results at a concentration of 500 mg/mL showed activity in the strong category, namely 13.70 ± 0.10 mm (Escherichia coli) and 12.93 ± 0.06 mm (Pseudomonas aeruginosa), and the minimum inhibitory concentration was at a concentration of 3.125 mg/mL. Conclusion the ethanol extract of kemangi leaves shows antibacterial activity.

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Anti-Acne Activity From Biocellulose Mask Formula Containing (Aloe Vera (L.) Burm.F) Essence Combined With Vitamin E

Cited by 8 publications

References 0 publications

Phytochemical Screening and Formulation of Hand Sanitizer Gel Preparations from Temu Hitam Rhizome Extract (Curcuma aeruginosa Roxb)

Phytochemical Screening and Formulation of Hand Sanitizer Gel Preparations from Temu Hitam Rhizome Extract (Curcuma aeruginosa Roxb)

Antibacterial Potential Of Ethanol Extract Of Tamarind Seed Bark (Tamarindus indica L.) And Formulation Of Anti-Acne Nanogel

Antibacterial Activity Ethanolic Extract of Ocimum basilicum L. Leaves in Inhibiting the Growth of Escherichia coli and Pseudomonas aeruginosa

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