Anthelmintic resistance of horse strongyle nematodes to fenbendazole in Lithuania

Dauparaitė, Evelina; Kupčinskas, Tomas; Várady, Marián; Petkevičius, Saulius

doi:10.1186/s13028-022-00645-y

Cited by 4 publications

(1 citation statement)

References 37 publications

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“…There is consensus that FECRT are important at individual premises level and should be performed regularly; with proposed methodology having been published recently. 73 Previous reports had stated minimum pretreatment FEC results of 40-200 epg, 129,[141][142][143][158][159][160][161] with resistance defined as a reduction <95% for macrocyclic lactones (ML), <90% for FBZ and PYR with lower confidence limits of 90% for MLs and 80% for BZ and PYR. 129,142,143,[162][163][164] However, these studies have been superseeded by the recent publication of the WAAVP guidelines.…”

Section: When and How Should Fecrt Be Used To Assess Cyathostomin Sta...mentioning

confidence: 99%

BEVA primary care clinical guidelines: Equine parasite control

Rendle,

Hughes,

Bowen

et al. 2024

Equine Veterinary Journal

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BackgroundThere is a lack of consensus on how best to balance our need to minimise the risk of parasite‐associated disease in the individual horse, with the need to limit the use of anthelmintics in the population to preserve their efficacy through delaying further development of resistance.ObjectivesTo develop evidence‐based guidelines utilising a modified GRADE framework.MethodsA panel of veterinary scientists with relevant expertise and experience was convened. Relevant research questions were identified and developed with associated search terms being defined. Evidence in the veterinary literature was evaluated using the GRADE evidence‐to‐decision framework. Literature searches were performed utilising CAB abstracts and PubMed. Where there was insufficient evidence to answer the research question the panel developed practical guidance based on their collective knowledge and experience.ResultsSearch results are presented, and recommendation or practical guidance were made in response to 37 clinically relevant questions relating to the use of anthelmintics in horses.Main limitationsThere was insufficient evidence to answer many of the questions with any degree of certainty and practical guidance frequently had to be based upon extrapolation of relevant information and the panel members' collective experience and opinions.ConclusionsEquine parasite control practices and current recommendations have a weak evidence base. These guidelines highlight changes in equine parasite control that should be considered to reduce the threat of parasite‐associated disease and delay the development of further anthelmintic resistance.

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Section: When and How Should Fecrt Be Used To Assess Cyathostomin Sta...mentioning

confidence: 99%

BEVA primary care clinical guidelines: Equine parasite control

Rendle,

Hughes,

Bowen

et al. 2024

Equine Veterinary Journal

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A systematic review and meta-analysis on the current status of anthelmintic resistance in equine nematodes: A global perspective

Cai,

Wu,

et al. 2024

Molecular and Biochemical Parasitology

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Efficacy of Bimectin® Anthelminthic against Helminthiasis in Horses in the Tyumen Region Conditions

Kalugina

Столбова²

2023

Vetpat

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Introduction. Helminthic infestation in horses is one of the most important problems the veterinary specialists face today, because helminth end-products affect significantly the overall condition of animals. The weight loss, depression, impaired work capacity, deterioration of stamina, exterior characteristics and natural resistance are observed and all together create the favourable conditions for arising the diseases of various etiology and cause considerable damage to horse breeding industry. The aim of the research is to determine the therapeutic efficacy of the anthelminthic drug «Bimectin®» against the intestinal helminthiasis in horses in the Tyumen region conditions.Materials and Methods. The studies were carried out with regard to the clinical examinations of animals and in compliance with the generally accepted parasitological methods. The infestation intensity (II), extensive efficacy (EE) and intensive efficacy (IE) were assessed, the haematological and biochemical blood tests were made on the 7th and 14th day before and after applying the drug. The results were statistically processed using the Statistica 6.1 software.Results. When assessing the therapeutic efficacy, we have determined that at a single application in the dose of 1.13 g. per 100 kg. of animal weight, the anthelminthic drug «Bimectin®» turned out to be 100 % therapeutically efficient and well tolerated by horses infested with Oxyuris equi and suborder Strongylata helminths, 91.7 % efficient against Parascaris equorum and 83.3 % efficient against Strongyloides westeri helminths.Discussion and Conclusions. Thus, in the result of assessing the therapeutic efficacy of the anthelmintic drug «Bimectin» against the horse helminthiasis, its economic benefit for using at the horse breeding farms of the region was confirmed, which should be taken into account when planning the combat measures against the nematode infestation in horses.

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Anthelmintic resistance of horse strongyle nematodes to fenbendazole in Lithuania

Cited by 4 publications

References 37 publications

BEVA primary care clinical guidelines: Equine parasite control

BEVA primary care clinical guidelines: Equine parasite control

A systematic review and meta-analysis on the current status of anthelmintic resistance in equine nematodes: A global perspective

Efficacy of Bimectin® Anthelminthic against Helminthiasis in Horses in the Tyumen Region Conditions

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