Anthelmintic efficiency of ivermectin against naturally acquired bovine gastrointestinal nematodes

Abstract

Ivermectin, one of the new avermectin group of anthelmintics, was more than 99 per cent effective in removing all stages of Ostertagia ostertagi including inhibited larvae, and adult Trichostrongylus axei when administered to cattle orally at 100 microgram/kg body-weight or subcutaneously at 100 and 200 microgram/kg body-weight. High efficacy (> 98.6 per cent) was also obtained against adults and inhibited larvae of Cooperia oncophora at 100 microgram/kg orally or 200 microgram/kg by subcutaneous injection. The latter treatment caused an 82.3 per cent reduction of adult Nematodirus helvetianus.

Ivermectin: a review of efficacy and safety

“…Nematodes. Ivermectin is active against essentially all of the gastrointestinal nematode species that are generally regarded as being of pathogenic or economic importance in cattle; and, except in the case of one species (below), a high degree of efficacy is achieved with the standard dosage (Armour et al, 1980;Benz & Ernst, 1981a, b;Egertonet al, 1981b;Yazwinski et al, 1981b;Lyons et al, 1981b;Elliott & Julian, 1981).The drug is also effective against the extraintestinal nematodes Dicty ocaulus viviparus (Benz & Emst, 1981b;Egerton et al, 1981b;Lyons et al, 1981b) and Parafilaria bovicola (Swan e t al., 1983) those species in which tests have been made against inhibited or hypobiotic fourth-stage larvae, or against strains resistant to other anthelmintics, ivermectin has consistently been highly effective against such stages and strains. The drug is about equally effective against nematodes when given orally or parenterally.…”

A comparative study on the efficacy of four anthelmintics on some important reindeer parasites

“…The overall terapeutic dose in cattle and sheep is found to be 200 meg Ivermectin/kg bodyweight subcutaneously injected (Armour et. al.…”

Identificação de Cooperia punctata (Linstow, 1907) resistente a ivermectina e doramectina em um rebanho leiteiro no Estado do Rio de Janeiro, Brasil

“…1 The avermectins are widely used as an anthelmintic for cattle in Brazil and around the world because of its high efficacy against a broad spectrum of nematode parasites and certain ectoparasites. Several studies have reported the efficacy of ivermectin 2,3,4,5 , doramectin 6,7,8,9,10 and abamectin 11,12,13,14 against the most important cattle gastrointestinal nematodes, the efficacy against adult Cooperia punctata of 95% is demonstrated.…”