Anthelmintic constituents from ginger (Zingiber officinale) against Hymenolepis nana

Lin, Rong-Jyh; Chen, Chung‐Yi; Lu, Chin-Mei; Ma, Yi-Hsuan; Chung, Li-Yu; Wang, Jhi-Joung; Lee, June-Der; Yen, Chuan-Min

doi:10.1016/j.actatropica.2014.07.009

Cited by 41 publications

(12 citation statements)

References 30 publications

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“…The SHG coefficients are calculated by our improved calculation formula [36], which has been successfully applied on a lot of NLO crystals such as BIBO [13], NaNO 2 [37], and KDP [38]. It is well known that the band-gap calculated by GGA is usually smaller than the experimental data due to the discontinuity of exchange-correlation energy.…”

Section: Methodsmentioning

confidence: 99%

Experimental and theoretical studies of second harmonic generation for Bi2O2[NO3(OH)]

Cong

Yang

Liao

et al. 2012

Materials Research Bulletin

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Section: Methodsmentioning

confidence: 99%

Experimental and theoretical studies of second harmonic generation for Bi2O2[NO3(OH)]

Cong

Yang

Liao

et al. 2012

Materials Research Bulletin

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“…The most abundant compounds are α-zingiberene, responsible for the distinctive flavor and aroma, geranial, ar-curcumene, β-bisabolene, β-sesquiphellandrene and neral [ 27 , 44 , 45 , 46 ]. Other pungent constituents found in lower amount are gingerol and shogaol [ 47 ].…”

Section: Chemical Composition Of Essential Oils Obtained From Genumentioning

confidence: 99%

“…However, the amount and the composition of the bioactive substances may vary among different Zingiber species, and, according to different factors such as the extraction methods, the geographic and the growing conditions, the harvest time, etc. [ 46 , 47 , 48 , 49 ]. Table 1 shows the major constituents of EOs from different Zingiber species, the extraction methods used and their biological activities.…”

Section: Chemical Composition Of Essential Oils Obtained From Genumentioning

confidence: 99%

Plants of the Genus Zingiber as a Source of Bioactive Phytochemicals: From Tradition to Pharmacy

et al. 2017

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Plants of the genus Zingiber (Family Zingiberaceae) are widely used throughout the world as food and medicinal plants. They represent very popular herbal remedies in various traditional healing systems; in particular, rhizome of Zingiber spp. plants has a long history of ethnobotanical uses because of a plethora of curative properties. Antimicrobial activity of rhizome essential oil has been extensively confirmed in vitro and attributed to its chemical components, mainly consisting of monoterpene and sesquiterpene hydrocarbons such as α-zingiberene, ar-curcumene, β-bisabolene and β-sesquiphellandrene. In addition, gingerols have been identified as the major active components in the fresh rhizome, whereas shogaols, dehydrated gingerol derivatives, are the predominant pungent constituents in dried rhizome. Zingiber spp. may thus represent a promising and innovative source of natural alternatives to chemical food preservatives. This approach would meet the increasing concern of consumers aware of the potential health risks associated with the conventional antimicrobial agents in food. This narrative review aims at providing a literature overview on Zingiber spp. plants, their cultivation, traditional uses, phytochemical constituents and biological activities.

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“…This may be attributed to the bioactive compounds of ginger; [10]-shogaol, [6]-shogaol,[10]-gingerol, [6]-gingerol, and hexahydro curcumin. It was observed that the morphology of Hymenolepis nana adult worms damaged by these compounds, especially in scolox and proglottid segment (Lin et al 2014). Lin et al (2010) found that the ginger constituents have larvicidal activity against Angiostrongylus cantonensis larvae by the direct killing or reducing their spontaneous movement.…”

Section: Discussionmentioning

confidence: 99%

Efficacy of Zingiber officinale ethanol extract on the viability, embryogenesis and infectivity of Toxocara canis eggs

El-Sayed

2017

J Parasit Dis

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This study evaluated the effect of e (e) ethanol extract on the viability, embryogenesis and infectivity () eggs. It was carried out both in vitro and in vivo. In the in vitro experiment, unembryonated eggs were incubated with 25, 50 and 100 mg/mLe extract at 25 °C for 6, 12, and 24 h to assess the effect of e on their viability and for two weeks to assess the effect ofe on their embryogenesis. In vivo experiment was performed to assess the effect of e on infectivity of eggs. Treated embryonated eggs by extract at concentrations of 25, 50 and 100 mg/mL for 24 h were inoculated into mice and their livers were examined for the presence of larvae on the 7th day after infection and for histopathological evaluation at 14th day post-infection. e showed a significant ovicidal activity on eggs. The best effect was observed with 100 mg/mL concentration after 24 h with an efficacy of 98.2%. However, the treated eggs by 25, 50 mg/mL of extract after 24 h showed ovicidal activity by 59.22 and 82.5% respectively. Moreover, this extract effectively inhibited eggs embryogenesis by 99.64% and caused their degeneration at the concentration of 100 mg/mL after 2 weeks of treatment. However, the lower concentrations, 25 and 50 mg/mL inhibited embryogenesis by 51.19 and 78.57% respectively. The effect of e on the infectivity eggs was proven by the reduction of larvae recovery in the livers by 35.9, 62.8 and 89.5% in mice groups inoculated by treated eggs at concentrations of 25, 50 and 100 mg/mL respectively. Histopathologically, the liver tissues of mice infected with treated eggs at the concentration of 100 mg/mL appeared healthy with slight degenerative changes of hepatocytes, opposite to that recorded in the infected mice with treated eggs by the lower concentrations. In conclusion; extract possessed dose-dependent anti- activity on the viability, embryogenesis and infectivity of eggs.

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Anthelmintic constituents from ginger (Zingiber officinale) against Hymenolepis nana

Cited by 41 publications

References 30 publications

Experimental and theoretical studies of second harmonic generation for Bi2O2[NO3(OH)]

Experimental and theoretical studies of second harmonic generation for Bi2O2[NO3(OH)]

Plants of the Genus Zingiber as a Source of Bioactive Phytochemicals: From Tradition to Pharmacy

Efficacy of Zingiber officinale ethanol extract on the viability, embryogenesis and infectivity of Toxocara canis eggs

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