Anthelmintic activity of Butea monosperma

D’Souza, Paschal; Asha, M.K.; Agarwal, Amit; Padmaja, R.

doi:10.1016/s0367-326x(00)00333-6

Cited by 39 publications

(22 citation statements)

References 2 publications

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“…Though the efficacy was not comparable with the levamisole, the reference drug used for positive anthelmintic control for the control of the haemonchosis of sheep and goat in field conditions but research out is of considerable importance. The present finding is in agreement with the previous published research work (Prashant et al 2001;Iqbal et al 2006). The phytochemical analysis revealed the high concentration of total phenolic and flavonoids content in the plant suggesting it as a good candidate for anthelmintic activity.…”

Section: Discussionsupporting

confidence: 93%

“…Based on the relevant ethno-botanical literature, we choose the seeds of B. monosperma (Lam.) Kuntze with promising anthelmintic property especially for roundworms and tapeworms (Prashant et al 2001;Iqbal et al 2006). The plant is highly used in indigenous systems of medicine as astringent, anticonvulsant, antioxidant, antistress, memory and behaviour stimulant, antigout, diuretic, antileprotic, antiulcer, antihepatotoxic, aphrodisiac, antibacterial and antihyperglycemic (Somani et al 2006;Bavarva and Narasimhacharya 2008;Sehrawat and Kumar 2012).…”

Section: Description Of Plant Materials and Proximate Analysismentioning

confidence: 99%

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Anthelmintic efficacy of aqueous extract of Butea monosperma (Lam.) Kuntze against Haemonchus contortus of sheep and goats

et al. 2013

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Infection with Haemonchus contortus is one of the most important economic problems in small ruminants worldwide. Resistance development by parasites, drug residues in meat, toxicity, non-availability and high cost limit the usefulness of currently used synthetic drugs. Therefore, the present study was undertaken to evaluate in vitro anthelmintic efficacy of aqueous extract of seeds of Butea monosperma (Lam.) Kuntze against H. contortus. Phytochemical analysis of extract showed high concentration of phenolic (11.93 ± 0.64 mg of GAE/g of extract), flavonoids (238.17 ± 19.14 mg of quercetin/g extract) and tannin (10.80 ± 0.70 mg of GAE/g of extract) content. The observations revealed that parasites were sluggish and movement was little at 4 h post exposure of 25, 50 mg/ml and very sluggish in 100 mg/ml concentration. The extract showed complete mortality of the adult H. contortus worms at the concentrations of 100 mg/ml at the time exposure of 6 h and with the concentration of 50 mg/ml at the post exposure of 8 h. At 25 mg/ml concentration 50 % mortality was recorded at 6 h and complete at 8 h post exposure. The LC 50 at 6 and 8 h were 45.20 and 17.50 mg/ml respectively. Levamisole at concentration of 0.5 mg/ml caused 50 % mortality at 2 h post exposure and full mortality at 4 h post exposure. These cidal effects may be due to presence of high phenolic, flavonoids and tannin content in the extract. The results confirm the aqueous extract of B. monosperma (Lam.) Kuntze on adult H. contortus worms.

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Section: Discussionsupporting

confidence: 93%

Section: Description Of Plant Materials and Proximate Analysismentioning

confidence: 99%

Anthelmintic efficacy of aqueous extract of Butea monosperma (Lam.) Kuntze against Haemonchus contortus of sheep and goats

et al. 2013

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“…In the traditional medicine of Southern Rajasthan the seed powder of Abrus precatorius is used as abortifacient (Singh and Pandey, 1998) which coincides by the pharmacological validation (Sethi et al, 1990). Similarly the anthelmintics properties of Tribulus terrestris in traditional medicines is reported by Asha et al (2001); Prashanth et al (2001); Deepak et al (2002); which is due to spirostanol type saponin, tribulosin and ␤-sitosterol-d-glucoside. The application of fruit extract of Helicteres isora in gastrospasm is in accordance with the fact that it contain cucurbitacine (Bean et al, 1985), flavonoids (Romesh and Yuvarajan, 1995), neolignans (Tezuka et al, 1999) and rosmarinic acid (Satake et al, 1999).…”

Section: Resultsmentioning

confidence: 64%

Folk herbal medicines from tribal area of Rajasthan, India

Katewa

Chaudhary

Jain

2004

Journal of Ethnopharmacology

187

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“…The plant extracts exhibited other biological activities including aphrodisiac activity in male rats, 8) anthelmintic activity, 9,10) and dermal wound healing in rats. 11) Isolation of (Ϫ)-medicarpin with antifungal activity from this part of the plant has also been reported.…”

Section: )mentioning

confidence: 99%

Bioactive Flavonoids of the Flowers of Butea monosperma

et al. 2009

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Butea monosperma (LAM.) TAUB. (Fabaceae), known in Thai as Tong-kwoaw, is a medium sized deciduous tree of up to 50 feet high with stunning flower clusters, very conspicuous when in flower, and the trunk is usually crooked and twisted with irregular branches and rough, grey bark. The flowers are bright orange red, large and in rigid racemes. 1)This plant species has been found to display a wide variety of biological activities. The stem bark is used in indigenous medicine for the treatment of dyspepsia, diarrhea, dysentery, diabetes, ulcers, sore throat and snake bites.2) The flower extract showed antidiabetic effect in rats.3) The plant leaves exhibited antiinflammatory effect 4) and exerted effect on stress, anxiety and cognition in rats.5) Anti-diarrhoeal activity of the ethanolic extract of the stem bark 6) and anticonvulsive activity of the petroleum ether extract of the flowers 7) of this plant species in experimental animals have been reported. The plant extracts exhibited other biological activities including aphrodisiac activity in male rats, 8) anthelmintic activity, 9,10) and dermal wound healing in rats. 11) Isolation of (Ϫ)-medicarpin with antifungal activity from this part of the plant has also been reported. 12) From the flowers of this plant species the flavonoids butin (1), butein (2), butrin (3), isobutrin, palasitrin, coreopsin, isocoreopsin, sulphuresin, monospermoside (4), isomonospermoside (5) and 7,3Ј,4Ј-trihydroxyflavone (6) have been isolated. [13][14][15] Antihepatotoxic activity of the flower extract 16) and of compound 3 and isobutrin 17) has been observed. Compound 1 which was isolated from the seeds of this plant species showed estrogenic and postcoital anti-conceptive activity in rats.18) A lectin was also isolated from the seeds and was found to agglutinate human erythrocytes. The activity was inhibited by N-acetyl galactosamine and did not require a divalent ion.19) The euphane triterpenoid 3a-hydroxyeuph-25-ene and the alcohol 2,14-dihydroxy-11,12-dimethyl-8-oxo-octadec-11-enylcyclohexane have been isolated from the stem.20) The imide palasimide has been isolated from the pods of this plant species.21) Stigmasterol, stigmasterol-3-O-b-D-glucopyranoside and nonacosanoic acid were also among those isolated compounds. 15,20) As part of an ongoing project on bioactive compounds from Thai medicinal plants for the treatments of tropical diseases, the plant species was investigated and it was found that the EtOAc and MeOH extracts exhibited antimycobacterial activity. The present report deals with the One new dihydrochalcone, dihydromonospermoside (7), was isolated from the flowers of Butea monosperma together with three known chalcones, butein (2), monospermoside (4) and isoliquiritigenin (8), one flavone, 7,3 ,4 -trihydroxyflavone (6), four flavanones, (؊)-butin (1a), (؊)-butrin (3a), (؉)-isomonospermoside (5b) and (؊)-liquiritigenin (9a), and three isoflavones, formononetin (10), afrormosin (11) and formononetin-7-O-b b-D-glucopyranoside (12). The structure of the new compound was e...

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Anthelmintic activity of Butea monosperma

Cited by 39 publications

References 2 publications

Anthelmintic efficacy of aqueous extract of Butea monosperma (Lam.) Kuntze against Haemonchus contortus of sheep and goats

Anthelmintic efficacy of aqueous extract of Butea monosperma (Lam.) Kuntze against Haemonchus contortus of sheep and goats

Folk herbal medicines from tribal area of Rajasthan, India

Bioactive Flavonoids of the Flowers of Butea monosperma

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