The A. absinthium is commonly known as wormwood having antipyretic, antimicrobial, antifungal, diuretic and anti-inflammatory properties. Natural bioactive compounds like phenols and flavonoids are the important secondary metabolites in plant posses high scavenging ability of free radical and reactive oxygen species produced in mammals. To maximize these agents in the extract different solvents viz. aqueous, ethanolic and chloroform are used for the extraction procedure (among these different extractions). Current study was aimed to determine the levels of total phenolic, flavonoids and tannin contents. Observations suggested that ethanolic extract has significantly high (P<0.05) concentration of flavonoids, phenolic and tannin contents as compared to aqueous and chloroform extracts. Therefore, ethanolic extract of A. absinthium has greater potential to scavenge free radicals/ ROS and can produce more beneficial effects as compared to aqueous and chloroform extracts. [J Intercult Ethnopharmacol 2012; 1(2.000): 101-104

Infection with Haemonchus contortus is one of the most important economic problems in small ruminants worldwide. Resistance development by parasites, drug residues in meat, toxicity, non-availability and high cost limit the usefulness of currently used synthetic drugs. Therefore, the present study was undertaken to evaluate in vitro anthelmintic efficacy of aqueous extract of seeds of Butea monosperma (Lam.) Kuntze against H. contortus. Phytochemical analysis of extract showed high concentration of phenolic (11.93 ± 0.64 mg of GAE/g of extract), flavonoids (238.17 ± 19.14 mg of quercetin/g extract) and tannin (10.80 ± 0.70 mg of GAE/g of extract) content. The observations revealed that parasites were sluggish and movement was little at 4 h post exposure of 25, 50 mg/ml and very sluggish in 100 mg/ml concentration. The extract showed complete mortality of the adult H. contortus worms at the concentrations of 100 mg/ml at the time exposure of 6 h and with the concentration of 50 mg/ml at the post exposure of 8 h. At 25 mg/ml concentration 50 % mortality was recorded at 6 h and complete at 8 h post exposure. The LC 50 at 6 and 8 h were 45.20 and 17.50 mg/ml respectively. Levamisole at concentration of 0.5 mg/ml caused 50 % mortality at 2 h post exposure and full mortality at 4 h post exposure. These cidal effects may be due to presence of high phenolic, flavonoids and tannin content in the extract. The results confirm the aqueous extract of B. monosperma (Lam.) Kuntze on adult H. contortus worms.

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