Abstract:Neuroimmunological research has indicated that hypothalamic structures play an important role in the modulation of immunoresponsivity. We report that electrical stimulation of the anterior hypothalamus decreases the concentration of Immunoglobulin G (lgG) in rat serum. Male Sprague-Dawley rats were randomly assigned to either an anterior or dummy electrode group. Following the determination of baseline IgG concentrations animals were placed in an operant chamber where electrical stimulation was delivered to an… Show more
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