Antagonistic effects of dietary<i>Moringa oleifera</i>on hemato‐biochemical and oxidative stress of lead nitrate intoxicated Nile tilapia,<i>Oreochromis niloticus</i>

Kumar, E K S Vijaya; Midhun, Sebastian Jose; Vysakh, A.; James, T.J.

doi:10.1111/are.15478

Cited by 17 publications

(14 citation statements)

References 63 publications

(57 reference statements)

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“…Abdel‐Tawwab and Hamed (2020), reported that Psidium guajava reduced the negative effects of cypermethrin. Kiran Kumar et al (2021), found that Moringa oleifera had a protective effect against nitrate intoxication in Nile tilapia. Similar to this study, it has been shown that herbal and chitosan‐derived applications will provide a protective effect and survival of fish and protection against pollutants such as heavy metals and carbofuran (Hamed & Abdel‐Tawwab, 2021; Hamed & Osman, 2017).…”

Section: Discussionmentioning

confidence: 99%

Effects of dietary black cumin (Nigella sativa L.) oil on growth performance, hemato‐biochemical and histopathology of cypermethrin‐intoxicated Nile tilapia (Oreochromis niloticus)

Öz,

Üstüner,

Bölükbaş

2023

J World Aquaculture Soc

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This study was conducted to investigate the effects of dietary black cumin (Nigella sativa L.) oil on growth performance, hemato‐biochemical, and histopathology of cypermethrin‐intoxicated Nile tilapia. After determining the LC50 (96 h) value of cypermethrin, cypermethrin was added to the water at a ratio of 1:20 of this concentration, and the fish were fed for 42 days. To reduce the effects of cypermethrin, 1% black cumin oil was added to the fish feed as a potential protectant. Growth parameters, hematology, blood biochemistry, and histopathological changes of Nile tilapia were examined after the feeding period. In this study, the best growth was observed in the group fed with feed containing 1% black cumin oil, while the worst growth performance was observed in the group fed with water containing cypermethrin and without black cumin oil in the feed. As a result of the study, it was observed that black cumin oil added to the fish diet reduced the negative effects of water‐borne cypermethrin on growth, hematology, blood biochemistry, and histopathological parameters of Nile tilapia.

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Section: Discussionmentioning

confidence: 99%

Effects of dietary black cumin (Nigella sativa L.) oil on growth performance, hemato‐biochemical and histopathology of cypermethrin‐intoxicated Nile tilapia (Oreochromis niloticus)

Öz,

Üstüner,

Bölükbaş

2023

J World Aquaculture Soc

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“…The present results were comparable to those of Chandurvelan et al [ 14 ] and Hu et al [ 56 ], while Perna canaliculus was tested through exposure to several trace elements, and Mytilus coruscus was treated with toxic nanoparticles, respectively, which eventually resulted in poor physiological conditions and growth performance. Reduced growth metrics have also been consistently observed in several fish species owing to lead toxicity [ 10 , 18 , 57 ]. In contrast, the effect of heavy metals on growth was insignificant when Lampsilis siliquoidea was exposed to copper [ 58 ].…”

Section: Discussionmentioning

confidence: 99%

“…Several studies have shown that aquatic species pick up this kind of toxic metal following the concentrations present in the neighboring environment [ 4 , 17 ]. The biological equilibrium becomes highly threatened if the concentration of Pb grows beyond the tolerance limit in an aquatic ecosystem, ultimately resulting in the degradation of the entire ecosystem [ 14 , 18 ]. Thus, the higher the heavy metal discharge into the water, the greater the accumulation of heavy metals in the living tissues and sediments [ 19 ].…”

Section: Introductionmentioning

confidence: 99%

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Impact of Pb Toxicity on the Freshwater Pearl Mussel, Lamellidens marginalis: Growth Metrics, Hemocyto-Immunology, and Histological Alterations in Gill, Kidney, and Muscle Tissue

Chowdhury

Schneider

et al. 2023

Toxics

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Pb is one of the most extensively used harmful heavy metals in Bangladesh, and its occurrence in waters affects aquatic organisms significantly. The tropical pearl mussel, Lamellidens marginalis, was exposed to different concentrations (T1 21.93 mgL−1, T2 43.86 mgL−1, and T3 87.72 mgL−1) of Pb(NO3)2 and was evaluated against a control C 0 mgL−1 of Pb(NO3)2, followed by a 96 h acute toxicity test. The LC50 value was recorded as 219.32 mgL−1. The physicochemical parameters were documented regularly for each treatment unit. The values of % SGR, shell weight, soft tissue wet weight, and weight gain remained statistically higher for the control group in comparison with the treatment. No mortality was noted for control units, while a gradually decreased survival rate was recorded for the different treatment groups. Fulton’s condition factor was recorded as highest in the control and lowest in the T3 unit, while the condition indices did not vary between the control and treatment groups. The hemocyte was accounted as maximum in the control and T1, while minimum in T2 and T3. The serum lysosomal parameters also followed a similar pattern, and a significantly low level of lysosomal membrane stability, and serum lysosome activity was noted for T3 and T2 units in comparison to the control group. The histology of the gill, kidney, and muscle was well structured in the control group, while distinct pathologies were observed in the gill, kidney, and muscle tissue of different treatment groups. The quantitative comparison revealed that the intensity of pathological alteration increased as the dosage of Pb increased. The current study, therefore, indicated that intrusion of Pb(NO3)2 in the living medium significantly alters growth performance and hemocyte counts, and chronic toxicity induces histomorphological abnormalities in vital organs.

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“…Previous studies have shown that Pb causes the accumulation of heavy metals, histopathology, and neurotoxicity in fish (Lee et al, 2019 ; Shahjahan et al, 2022 ). Lead accumulation can also cause oxidative stress in aquatic organisms and damage the antioxidant function of the body (Guo et al, 2021 ; Kumar et al, 2021 ). Therefore, several antioxidant markers, such as antioxidant enzymes (GST and CAT) and glutathione (GSH), are often used to evaluate the toxic effects of Pb-induced oxidative stress.…”

Section: Introductionmentioning

confidence: 99%

Lead induced structural and functional damage and microbiota dysbiosis in the intestine of crucian carp (Carassius auratus)

Liu,

Zhang,

et al. 2023

Front. Microbiol.

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Lead (Pb) is a hazardous pollutant in water environments that can cause significant damage to aquatic animals and humans. In this study, crucian carp (Carassius auratus) were exposed to waterborne Pb for 96 h; then, histopathological analysis, quantitative qPCR analysis, and 16S high-throughput sequencing were performed to explore the effects of Pb on intestinal bioaccumulation, structural damage, oxidative stress, immune response, and microbiota imbalance of C. auratus. After Pb exposure, the intestinal morphology was obviously damaged, including significantly increasing the thickness of the intestinal wall and the number of goblet cells and reducing the depth of intestinal crypts. Pb exposure reduced the mRNA expressions of Claudin-7 and villin-1 while significantly elevated the level of GST, GSH, CAT, IL-8, IL-10, IL-1, and TNF-α. Furthermore, 16S rRNA analysis showed that the Shannon and Simpson indices decreased at 48 h after Pb exposure, and the abundance of pathogenic bacteria (Erysipelotrichaceae, Weeksellaceae, and Vibrionaceae) increased after Pb exposure. In addition, the correlation network analysis found that Proteobacteria were negatively correlated with Firmicutes and positively correlated with Bacteroidetes. Functional prediction analysis of bacteria speculated that the change in intestinal microbiota led to the PPAR signaling pathway and peroxisome function of the intestine of crucian carp was increased, while the immune system and membrane transport function were decreased. Finally, canonical correlation analysis (CCA) found that there were correlations between the intestinal microbiota, morphology, antioxidant factors, and immune factors of crucian carp after Pb exposure. Taken together, our results demonstrated that intestinal flora dysbiosis, morphological disruption, oxidative stress, and immune injury are involved in the toxic damage of Pb exposure to the intestinal structure and function of crucian carp. Meanwhile, Pb exposure rapidly increased the abundance of pathogenic bacteria, leading to intestinal disorders, further aggravating the damage of Pb to intestinal structure and function. These findings provide us a basis for the link between gut microbiome changes and heavy metal toxicity, and gut microbiota can be used as biomarkers for the evaluation of heavy metal pollution in future.

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Antagonistic effects of dietaryMoringa oleiferaon hemato‐biochemical and oxidative stress of lead nitrate intoxicated Nile tilapia,Oreochromis niloticus

Cited by 17 publications

References 63 publications

Effects of dietary black cumin (Nigella sativa L.) oil on growth performance, hemato‐biochemical and histopathology of cypermethrin‐intoxicated Nile tilapia (Oreochromis niloticus)

Effects of dietary black cumin (Nigella sativa L.) oil on growth performance, hemato‐biochemical and histopathology of cypermethrin‐intoxicated Nile tilapia (Oreochromis niloticus)

Impact of Pb Toxicity on the Freshwater Pearl Mussel, Lamellidens marginalis: Growth Metrics, Hemocyto-Immunology, and Histological Alterations in Gill, Kidney, and Muscle Tissue

Lead induced structural and functional damage and microbiota dysbiosis in the intestine of crucian carp (Carassius auratus)

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